Katsumasa Irie

Wakayama Medical University — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index1.5kcitations86works0.32yr avg
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Research Topics

Ion channel regulation and function(27), Intracranial Aneurysms: Treatment and Complications(18), Cerebrovascular and Carotid Artery Diseases(12), Nicotinic Acetylcholine Receptors Study(12), Neuroscience and Neuropharmacology Research(9)

Publications85 total

Structure-function analysis of the lithium-ion selectivity of the voltage-gated sodium channel
The Journal of General Physiology·2026Open Access
Cryo-EM structure of human AQP11 reveals a trimeric architecture with a large pore
Science Advances·2026Open Access
Conformational dynamics underlying slow inactivation in voltage-gated sodium channels
2025Open Access
Structure-function analysis of lithium-ion selectivity of voltage-gated sodium channel
2025Open Access
BPS2025 - Corporation of selectivity filter and activation gate in the C-type inactivation observed in prokaryotic sodium channels
Biophysical Journal·2025
Molecular Mechanism of Cooperative Opening of Voltage-gated Sodium Channels
Seibutsu Butsuri·2025Open Access
Analysis of the Divalent Cation Blocking in Ion Channels by Crystal Structure and Molecular Dynamics Simulations
YAKUGAKU ZASSHI·2024Open Access
Retraction Note: Genetic manipulation of autonomic nerve fiber innervation and activity and its effect on breast cancer progression
Nature Neuroscience·2024· 2 citedOpen Access
Voltage sensors of a Na+ channel dissociate from the pore domain and form inter-channel dimers in the resting state
Nature Communications·2023· 10 citedOpen Access
The structural basis of divalent cation block in a tetrameric prokaryotic sodium channel
Nature Communications·2023· 5 citedOpen Access
Interchannel dimerization of the dissociated voltage-sensor domains of voltage-gated Na+ channels in the resting state
Research Square (Research Square)·2023Open Access
Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human α2δ1, a Voltage-Gated Calcium Channel Subunit
Journal of Molecular Biology·2023· 14 citedOpen Access
The structural basis of the divalent cation blocking on tetrameric cation channel
2023Open Access
The structural basis of the divalent cation blocking on tetrameric cation channel
Figshare·2023Open Access
The structural basis of the divalent cation blocking on tetrameric cation channel
Figshare·2023Open Access
The recognition mechanism of the analgesic drug mirogabalin by recombinant human α<sub>2</sub>δ1 protein
Proceedings for Annual Meeting of The Japanese Pharmacological Society·2022Open Access
Gastric proton pump with two occluded K+ engineered with sodium pump-mimetic mutations
Nature Communications·2021· 10 citedOpen Access
Gastric proton pump with two occluded K+ engineered with sodium pump-mimetic mutations
2021Open Access
Crystal structure of the gastric proton pump K791S in (BYK)E2BeF state
2021
Crystal structure of the gastric proton pump K791S/E820D/Y340N in (BYK)E2BeF state
2021
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Frequent Co-authors

Yoshinori Fujiyoshi(23), Takushi Shimomura(13), Kazuhiro Abe(6), Hitoshi Nagura(6), Makoto Negoro(6), Hanayo Nakanishi(5), S. Nagao(5), Kouki Nishikawa(4), Tomoya Imai(4), Shigemasa Ikeda(4), Fumihito Arai(4), Toshio Fukuda(4), Hiroshi Suzuki(3), Yoko Hiroaki(3), Nobuyuki Kawai(3), K Kunishio(3), Tomoya Ogawa(3), Kenta Yamamoto(3), Atsunori Oshima(3), Takashi Sumikama(3)