Nady Roodi

Vanderbilt University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index4.0kcitations20works0.02yr avg
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Research Topics

Estrogen and related hormone effects(15), Glutathione Transferases and Polymorphisms(10), Pharmacogenetics and Drug Metabolism(5), DNA Repair Mechanisms(2), Epigenetics and DNA Methylation(2)

Publications20 total

Estrogen Metabolism and Exposure in a Genotypic–Phenotypic Model for Breast Cancer Risk Prediction
Cancer Epidemiology Biomarkers & Prevention·2011· 26 citedOpen Access
Estrogen Metabolism and Breast Cancer
Annals of the New York Academy of Sciences·2009· 70 citedOpen Access
Carcinogen-induced histone alteration in normal human mammary epithelial cells
Carcinogenesis·2007· 43 citedOpen Access
Cytochrome P450 1B1–Mediated Estrogen Metabolism Results in Estrogen-Deoxyribonucleoside Adduct Formation
Cancer Research·2007· 87 cited
Estrogens, Enzyme Variants, and Breast Cancer: A Risk Model
Cancer Epidemiology Biomarkers & Prevention·2006· 41 cited
In Vitro Model of Mammary Estrogen Metabolism:  Structural and Kinetic Differences between Catechol Estrogens 2- and 4-Hydroxyestradiol
Chemical Research in Toxicology·2004· 46 cited
Association of Homozygous Wild-Type Glutathione S-Transferase M1 Genotype with Increased Breast Cancer Risk
Cancer Research·2004· 69 citedOpen Access
Sequential action of phase I and II enzymes cytochrome p450 1B1 and glutathione S-transferase P1 in mammary estrogen metabolism.
PubMed·2003· 58 cited
Methoxyestrogens exert feedback inhibition on cytochrome P450 1A1 and 1B1.
PubMed·2003· 78 cited
Catechol-O-methyltransferase (COMT)-mediated metabolism of catechol estrogens: comparison of wild-type and variant COMT isoforms.
PubMed·2001· 252 cited
Multifactor-Dimensionality Reduction Reveals High-Order Interactions among Estrogen-Metabolism Genes in Sporadic Breast Cancer
The American Journal of Human Genetics·2001· 1.9k citedOpen Access
Cytochrome P450 1B1 (CYP1B1) pharmacogenetics: association of polymorphisms with functional differences in estrogen hydroxylation activity.
PubMed·2000· 313 cited
Association of cytochrome P450 1B1 (CYP1B1) polymorphism with steroid receptor status in breast cancer.
PubMed·1998· 222 cited
Breast cancer and CYPIA1, GSTM1, and GSTT1 polymorphisms: evidence of a lack of association in Caucasians and African Americans.
PubMed·1998· 214 cited
High-Mobility Group (HMG) Protein HMG-1 and TATA-Binding Protein-Associated Factor TAF<sub>II</sub>30 Affect Estrogen Receptor-Mediated Transcriptional Activation
Molecular Endocrinology·1997· 70 cited
Analysis of the estrogen receptor (ER) gene, transcript and protein in ER-positive and -negative breast cancer cell lines
Endocrine Related Cancer·1995· 1 cited
The interaction of the estrogen receptor with its DNA response element is facilitated by the high mobility group protein, HMG-1
1995· 4 cited
Estrogen Receptor Gene Analysis in Estrogen Receptor-Positive and Receptor-Negative Primary Breast Cancer
JNCI Journal of the National Cancer Institute·1995· 267 cited
Microsatellite instability and loss of heterozygosity in breast cancer.
PubMed·1994· 189 cited
Reactivity of alpha 1-antitrypsin mutants against proteolytic enzymes of the kallikrein-kinin, complement, and fibrinolytic systems.
Journal of Biological Chemistry·1990· 44 citedOpen Access

Frequent Co-authors

Fritz F. Parl(19), Sheila Dawling(9), Lisa Bailey(5), William D. Dupont(5), C S Verrier(5), Cindy J. Yee(5), David L. Hachey(4), Philip S. Crooke(3), Marylyn D. Ritchie(2), Jason H. Moore(2), Ray Mernaugh(2), Roy A. Jensen(2), Michael Bustin(2), Lance W. Hahn(1), Imad H Hanna(1), F. Peter Guengerich(1), W Y Kao(1), Xiahong Wang(1), L R Bailey(1), W.D. Dupont(1)