Wilson Cúnico

Universidade Federal de Pelotas — Brazil

Chemistry · Physical Sciences

23h-index1.7kcitations156works3.02yr avg
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Research Topics

Synthesis and biological activity(64), Crystallization and Solubility Studies(35), X-ray Diffraction in Crystallography(35), Synthesis and Characterization of Heterocyclic Compounds(26), Synthesis of heterocyclic compounds(21)

Publications156 total

Novel Hit Compounds Against a Neglected Sexually Transmitted Infection: Synthesis and Trichomonacidal Activity of 1,3-Thiazolidin-4-One Derivatives
Pharmaceutics·2026Open Access
3-(3-(diethylamino)propyl)-2-(4-(methylthio)phenyl)thiazolidin-4-one Attenuates Scopolamine-induced Cognitive Impairment in Rats: Insights Into Neuroprotective Effects
Molecular Neurobiology·2025· 5 cited
Exploring the structure-activity relationship (SAR) of Schiff bases as effective compounds in scavenging free radicals
Journal of Molecular Structure·2024· 7 cited
Exploring the Strucutre-Activity Relationship (Sar) of Schiff Bases as Effective Compounds in Scavenging Free Radicals
SSRN Electronic Journal·2024Open Access
Therapeutic potential of blackberry extract in the preventing memory deficits and neurochemical alterations in the cerebral cortex, hippocampus and cerebellum of a rat model with amnesia
Metabolic Brain Disease·2023· 14 cited
Thiazolidin-4-one prevents against memory deficits, increase in phosphorylated tau protein, oxidative damage and cholinergic dysfunction in Alzheimer disease model: Comparison with donepezil drug
Brain Research Bulletin·2022· 9 citedOpen Access
Thiazolidine-2,4-dione derivative exhibits antitumoral effect and reverts behavioral and metabolic changes in a model of glioblastoma
Metabolic Brain Disease·2022· 2 cited
Effect of Thiazolidin-4-one Against Lipopolysaccharide—Induced Oxidative Damage, and Alterations in Adenine Nucleotide Hydrolysis and Acetylcholinesterase Activity in Cultured Astrocytes
Cellular and Molecular Neurobiology·2022· 6 citedOpen Access
CCDC 1562762: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
Synthesis and Biological Evaluation of Novel 2-imino-4-thiazolidinones asPotential Antitumor Agents for Glioblastoma
Medicinal Chemistry·2021· 8 cited
Three ‐(pyridin‐2‐yl)‐2‐(pyridin‐2‐ylimino)thiazolidin‐4‐one as a novel inhibitor of cerebral MAO‐B activity with antioxidant properties and low toxicity potential
Journal of Biochemical and Molecular Toxicology·2021· 10 cited
Multitarget Effect of 2-(4-(Methylthio)phenyl)-3-(3-(piperidin-1-yl)propyl)thiazolidin-4-one in a Scopolamine-Induced Amnesic Rat Model
Neurochemical Research·2021· 6 cited
2,4-Thiazolidinedione as Precursor to the Synthesis of Compounds with Anti-glioma Activities in C6 and GL261 Cells
Medicinal Chemistry·2020· 5 cited
In Vitro Effects of 2-{4-[Methylthio(methylsulfonyl)]phenyl}-3-substitutedthiazolidin-4-ones on the Acetylcholinesterase Activity in Rat Brain and Lymphocytes: Isoform Selectivity, Kinetic Analysis, and Molecular Docking
Neurochemical Research·2019· 9 cited
Synthesis of thiazolidin-4-ones and thiazinan-4-ones from 1-(2-aminoethyl)pyrrolidine as acetylcholinesterase inhibitors
Journal of Enzyme Inhibition and Medicinal Chemistry·2019· 18 citedOpen Access
2-(2-Methoxyphenyl)-3-((Piperidin-1-yl)ethyl)thiazolidin-4-One-Loaded Polymeric Nanocapsules: In Vitro Antiglioma Activity and In Vivo Toxicity Evaluation
Cellular and Molecular Neurobiology·2019· 11 citedOpen Access
Synthesis of Novel Thiazolidin‐4‐ones and Thiazinan‐4‐ones Analogous to Rosiglitazone
Journal of Heterocyclic Chemistry·2018· 6 citedOpen Access
Synthesis and biological evaluation of benzothiazin-4-ones: a possible new class of acetylcholinesterase inhibitors
Journal of Enzyme Inhibition and Medicinal Chemistry·2018· 13 citedOpen Access
Endophytic Fungus Isolated From Achyrocline satureioides Exhibits Selective Antiglioma Activity—The Role of Sch-642305
Frontiers in Oncology·2018· 25 citedOpen Access
Ovicidal in vitro activity of 2-aryl-3-(2-morpholinoethyl)thiazolidin-4-ones and 2-aryl-3-(3-morpholinopropyl)thiazolidin-4-ones against Fasciola hepatica (Linnaeus, 1758)
Experimental Parasitology·2018· 14 cited
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Frequent Co-authors

Cláudio Martin Pereira de Pereira(16), Marcos A. P. Martins(14), Hélio G. Bonacorso(14), Nilo Zanatta(14), Cláudia R. B. Gomes(12), Geonir M. Siqueira(11), Patrícia D. Neuenfeldt(7), Bruna Bento Drawanz(7), Rosélia Maria Spanevello(7), Alex F. C. Flores(6), Antoniana U. Krettli(6), Francieli Moro Stefanello(6), Mayara Sandrielly Pereira Soares(6), Daniela P. Gouvêa(5), Marcele Moreth(5), Adilson Paulo Sinhorin(4), M.V.N. De Souza(4), Walcimar T. Vellasco(4), Fernanda A. Rosa(4), Paulo Beck(4)