Italia Grenga

AstraZeneca (United States) — United States

Medicine · Health Sciences

22h-index2.0kcitations98works0.02yr avg
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Research Topics

Cancer Immunotherapy and Biomarkers(42), Immunotherapy and Immune Responses(27), Angiogenesis and VEGF in Cancer(19), Immune Cell Function and Interaction(11), Colorectal Cancer Treatments and Studies(11)

Publications96 total

Abstract 2957: Establishing preclinical activity of topoisomerase I inhibitor (TOPO1i) antibody-drug conjugate AZD9592 in patient-derived xenograft (PDX) models of metastatic colorectal cancer (mCRC) in context of irinotecan pretreatment and resistance
Cancer Research·2025
Abstract 2961: AZD9592, an EGFR/cMET bispecific antibody-drug conjugate (ADC), demonstrates target-dependent efficacy in colorectal cancer (CRC) patient-derived xenograft (PDX) models
Cancer Research·2025
Abstract 2023: Multiplex immunofluorescence profiling of the tumor microenvironment and CD73: Activity of neoadjuvant oleclumab in patients with non-small-cell lung cancer in NeoCOAST
Cancer Research·2024
P2.04-03 EGRET: First-in-human Study of the Novel Antibody-drug Conjugate AZD9592 ± Anti-cancer Agents in Advanced Solid Tumours
Journal of Thoracic Oncology·2023Open Access
Supplementary Figure 2 from Immune Consequences of Decreasing Tumor Vasculature with Antiangiogenic Tyrosine Kinase Inhibitors in Combination with Therapeutic Vaccines
2023Open Access
Data from Analyses of Pretherapy Peripheral Immunoscore and Response to Vaccine Therapy
2023Open Access
Data from Analyses of Pretherapy Peripheral Immunoscore and Response to Vaccine Therapy
2023Open Access
Supplementary Figures 1 through 3 and Supplementary Tables 1 through 3 from Analyses of Pretherapy Peripheral Immunoscore and Response to Vaccine Therapy
2023Open Access
Supplementary Figure 1 from Immune Consequences of Decreasing Tumor Vasculature with Antiangiogenic Tyrosine Kinase Inhibitors in Combination with Therapeutic Vaccines
2023Open Access
Supplementary Figures 1 through 3 and Supplementary Tables 1 through 3 from Analyses of Pretherapy Peripheral Immunoscore and Response to Vaccine Therapy
2023Open Access
Supplementary Figure 3 from Immune Consequences of Decreasing Tumor Vasculature with Antiangiogenic Tyrosine Kinase Inhibitors in Combination with Therapeutic Vaccines
2023Open Access
Supplementary Figure 4 from Immune Consequences of Decreasing Tumor Vasculature with Antiangiogenic Tyrosine Kinase Inhibitors in Combination with Therapeutic Vaccines
2023Open Access
Supplemental Figure 1 from Phase I Trial of a Yeast-Based Therapeutic Cancer Vaccine (GI-6301) Targeting the Transcription Factor Brachyury
2023Open Access
Data Supplement from Immune Consequences of Decreasing Tumor Vasculature with Antiangiogenic Tyrosine Kinase Inhibitors in Combination with Therapeutic Vaccines
2023Open Access
Supplementary Figure 3 from Immune Consequences of Decreasing Tumor Vasculature with Antiangiogenic Tyrosine Kinase Inhibitors in Combination with Therapeutic Vaccines
2023Open Access
Supplementary Materials and Methods from Analyses of Pretherapy Peripheral Immunoscore and Response to Vaccine Therapy
2023Open Access
Data from Phase I Trial of a Yeast-Based Therapeutic Cancer Vaccine (GI-6301) Targeting the Transcription Factor Brachyury
2023Open Access
Supplementary Figure 2 from Immune Consequences of Decreasing Tumor Vasculature with Antiangiogenic Tyrosine Kinase Inhibitors in Combination with Therapeutic Vaccines
2023Open Access
Supplemental Figure 1 from Phase I Trial of a Yeast-Based Therapeutic Cancer Vaccine (GI-6301) Targeting the Transcription Factor Brachyury
2023Open Access
Supplementary Materials and Methods from Analyses of Pretherapy Peripheral Immunoscore and Response to Vaccine Therapy
2023Open Access
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Frequent Co-authors

Renee N. Donahue(36), Jeffrey Schlom(35), James L. Gulley(30), Christopher R. Heery(27), Ravi A. Madan(26), Lauren M. Lepone(22), Benedetto Farsaci(16), Mario Roselli(12), Caroline Jochéms(11), Jennifer L. Marté(9), Vincenzo Formica(8), Fiorella Guadagni(8), Lisa M. Cordes(7), Jacob Richards(7), William L. Dahut(6), Patrizia Ferroni(5), Julius Strauss(4), Romaine I. Fernando(4), James W. Hodge(4), Ilaria Portarena(4)