Enrico Spiga

The Francis Crick Institute — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index361citations22works0.02yr avg
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Research Topics

Protein Structure and Dynamics(8), Lipid Membrane Structure and Behavior(4), Enzyme Structure and Function(4), Hemoglobin structure and function(4), Bacterial Genetics and Biotechnology(3)

Publications22 total

Probing the early stages of prion protein (PrP) aggregation with atomistic molecular dynamics simulations
Chemical Communications·2018· 14 cited
Genome sequence of a diabetes-prone rodent reveals a mutation hotspot around the ParaHox gene cluster
Proceedings of the National Academy of Sciences·2017· 38 citedOpen Access
Genome sequence of a diabetes-prone desert rodent reveals a mutation hotspot around the ParaHox gene cluster
2016· 1 citedOpen Access
Molecular Effects of Concentrated Solutes on Protein Hydration, Dynamics, and Electrostatics
Biophysical Journal·2016· 37 citedOpen Access
Assembly of Influenza Hemagglutinin Fusion Peptides in a Phospholipid Bilayer by Coarse-grained Computer Simulations
Frontiers in Molecular Biosciences·2015· 10 citedOpen Access
Dissecting the Effects of Concentrated Carbohydrate Solutions on Protein Diffusion, Hydration, and Internal Dynamics
The Journal of Physical Chemistry B·2014· 21 citedOpen Access
New Strategies for Integrative Dynamic Modeling of Macromolecular Assembly
Advances in protein chemistry and structural biology·2014· 15 citedOpen Access
All-atom simulations of crowding effects on ubiquitin dynamics
Physical Biology·2013· 15 citedOpen Access
Electrostatic-Consistent Coarse-Grained Potentials for Molecular Simulations of Proteins
Journal of Chemical Theory and Computation·2013· 32 citedOpen Access
Structure–Function Paradigm in Human Myoglobin: How a Single-Residue Substitution Affects NO Reactivity at Low pO<sub>2</sub>
Journal of the American Chemical Society·2013· 7 cited
Multiscale simulations of protein dynamics
Infoscience (Ecole Polytechnique Fédérale de Lausanne)·2013Open Access
Human Myoglobin: Two Isoforms that Differ at Single Residue. Their Different Dynamics Suggest Distinct and Complementary Role
Biophysical Journal·2011· 1 citedOpen Access
Development of a chemical-detailed coarse-grained force field for proteins
Infoscience (Ecole Polytechnique Fédérale de Lausanne)·2011Open Access
Human myoglobins: paradigm of structure-function relation
UNICA IRIS Institutional Research Information System (University of Cagliari)·2011
Molecular Basis of Enrofloxacin Translocation through OmpF, an Outer Membrane Channel of Escherichia coli - When Binding Does Not Imply Translocation
The Journal of Physical Chemistry B·2010· 103 cited
Coarse-graining electrostatics in multiscale molecular simulations
Infoscience (Ecole Polytechnique Fédérale de Lausanne)·2010Open Access
Drug design: Insights from atomistic simulations
UNICA IRIS Institutional Research Information System (University of Cagliari)·2009· 2 cited
The Biophysics Of Antibiotics Translocation Through OmpF Revealed By Computer Simulations
Biophysical Journal·2009Open Access
Structural Analysis of Hemoglobins and Myoglobins Using MD Simulations
Biophysical Journal·2009Open Access
Facilitated Permeation of Antibiotics across Membrane Channels − Interaction of the Quinolone Moxifloxacin with the OmpF Channel
Journal of the American Chemical Society·2008· 65 cited
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Frequent Co-authors

Matteo Ceccarelli(9), Paolo Ruggerone(7), Matteo Dal Peraro(7), Francesca Collu(4), Mariano Andrea Scorciapino(4), Mariano Casu(4), Eric Hajjar(3), Tivadar Mach(3), Amit Kumar(3), Mathias Winterhalter(3), Luciano A. Abriata(3), Davide Alemani(3), Michele Cascella(3), Kozhinjampara R. Mahendran(2), Helge Weingart(2), Paula Gameiro(2), Adam D Hargreaves(2), Long Zhou(2), Josef Christensen(2), Ferdinand Marlétaz(2)