Mohammed Bourdi

National Center for Advancing Translational Sciences — United States

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

28h-index3.0kcitations44works0.02yr avg
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Research Topics

Drug-Induced Hepatotoxicity and Protection(27), Pharmacogenetics and Drug Metabolism(9), Drug Transport and Resistance Mechanisms(7), Liver physiology and pathology(6), Liver Disease Diagnosis and Treatment(5)

Publications44 total

Evaluation of chronic toxicity of cyclocreatine, a creatine analog, in Sprague Dawley rat after oral gavage administration for up to 26 weeks
Regulatory Toxicology and Pharmacology·2020· 7 cited
Safety assessment of metarrestin in dogs: A clinical candidate targeting a subnuclear structure unique to metastatic cancer cells
Regulatory Toxicology and Pharmacology·2020· 7 citedOpen Access
Intravenous toxicity and toxicokinetics of an HDL mimetic, Fx-5A peptide complex, in cynomolgus monkeys
Regulatory Toxicology and Pharmacology·2018· 13 citedOpen Access
Corrigendum to “Differential susceptibility to acetaminophen-induced liver injury in sub-strains of C57BL/6 mice: 6N versus 6J” [Food and Chem. Toxicol. 98 (Part B) (2016) 107–118]
Food and Chemical Toxicology·2017
Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment
Nature Communications·2016· 75 citedOpen Access
Differential susceptibility to acetaminophen-induced liver injury in sub-strains of C57BL/6 mice: 6N versus 6J
Food and Chemical Toxicology·2016· 52 citedOpen Access
Drug‐induced allergic hepatitis develops in mice when myeloid‐derived suppressor cells are depleted prior to halothane treatment
Hepatology·2015· 65 citedOpen Access
Cell Ultrastructure and Distribution of Trifluoroacetylated Protein-Adducts in Early Hepatic Injury in Mice Induced by Inhalation Anesthetic, Halothane.
Microscopy and Microanalysis·2014
Thymic stromal lymphopoietin and interleukin-4 mediate the pathogenesis of halothane-induced liver injury in mice
Hepatology·2014· 17 citedOpen Access
Eosinophils mediate the pathogenesis of halothane-induced liver injury in mice
Hepatology·2012· 52 citedOpen Access
Endogenous Interleukin-4 Regulates Glutathione Synthesis Following Acetaminophen-Induced Liver Injury in Mice
Chemical Research in Toxicology·2011· 49 cited
SIRT3‐dependent deacetylation exacerbates acetaminophen hepatotoxicity
EMBO Reports·2011· 80 citedOpen Access
Mispairing C57BL/6 Substrains of Genetically Engineered Mice and Wild-Type Controls Can Lead to Confounding Results as It Did in Studies of JNK2 in Acetaminophen and Concanavalin A Liver Injury
Chemical Research in Toxicology·2011· 101 cited
Pathologic role of stressed-induced glucocorticoids in drug-induced liver injury in mice
Biochemical and Biophysical Research Communications·2010· 25 cited
Knockdown of ERp57 increases BiP/GRP78 induction and protects against hyperoxia and tunicamycin-induced apoptosis
American Journal of Physiology-Lung Cellular and Molecular Physiology·2009· 58 cited
Protective role of c-Jun N-terminal kinase 2 in acetaminophen-induced liver injury
Biochemical and Biophysical Research Communications·2008· 51 citedOpen Access
Hepatoprotective Role of Endogenous Interleukin-13 in a Murine Model of Acetaminophen-Induced Liver Disease
Chemical Research in Toxicology·2007· 67 cited
Role of IL-6 in an IL-10 and IL-4 Double Knockout Mouse Model Uniquely Susceptible to Acetaminophen-Induced Liver Injury
Chemical Research in Toxicology·2007· 87 cited
Genomic Identification of Potential Risk Factors during Acetaminophen-Induced Liver Disease in Susceptible and Resistant Strains of Mice
Chemical Research in Toxicology·2006· 49 cited
Role of interleukin-6 in hepatic heat shock protein expression and protection against acetaminophen-induced liver disease
Biochemical and Biophysical Research Communications·2003· 145 cited
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Frequent Co-authors

Lance R. Pohl(28), Timothy P. Reilly(10), Jackie L. Martin(9), John W. George(8), Philippe Beaune(7), Mala Chakraborty(6), Michael F. Radonovich(5), John Brady(5), Cynthia A. Pise-Masison(4), William R. Proctor(4), Pauline M. Ryan(4), Hamid Amouzadeh(3), J Nataf(3), Jacques Bernuau(3), Dominique Pessayre(3), Mary L. Graf(3), Dolores B. Njoku(3), Claire Belloc(3), Steven B. Yee(3), Kenrick Semple(3)