Yun C. Chang

Tianjin Third Central Hospital — China

Medicine · Health Sciences

57h-index9.7kcitations130works3.32yr avg
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Research Topics

Fungal Infections and Studies(89), Antifungal resistance and susceptibility(58), Plant-Microbe Interactions and Immunity(19), Plant Pathogens and Fungal Diseases(18), Nail Diseases and Treatments(15)

Publications130 total

Hypoxia-preconditioned cardiomyocyte-derived extracellular vesicles alleviate myocardial ischemic injury by reprogramming macrophage polarization via the Fgl2/NF-κB pathway
International Immunopharmacology·2025Open Access
A Tale of Two Responses: Vaccine vs. Natural Immunity in Young Atopic Children 2. Authors’ full names:
2025Open Access
Association between atherogenic index of plasma and physical dysfunction: a cross-sectional study of middle-aged and older adults in China
Frontiers in Public Health·2025· 2 citedOpen Access
Elevated UDP-glucuronic acid levels mend drug resistance and stress responses via a protease and a transporter in <i>Cryptococcus gattii</i>
Proceedings of the National Academy of Sciences·2025Open Access
<i>Solanum lycopersicum</i> derived exosome-like nanovesicles alleviate restenosis after vascular injury through the Keap1/Nrf2 pathway
Food & Function·2024· 16 citedOpen Access
Genetic mutations in Cryptococcus neoformans pyrimidine salvage pathway enzymes contribute to reduced susceptibility against 5-fluorocytosine
npj Antimicrobials and Resistance·2024· 3 citedOpen Access
Determination of Ploidy Levels and Nuclear DNA Content in Cryptococcus neoformans by Flow Cytometry: Drawbacks with Variability
Journal of Fungi·2024· 2 citedOpen Access
Inbred SJL mice recapitulate human resistance to <i>Cryptococcus</i> infection due to differential immune activation
mBio·2023· 10 citedOpen Access
<i>Cryptococcus neoformans</i> requires the <i>TVF1</i> gene for thermotolerance and virulence
Medical Mycology·2023· 8 citedOpen Access
Factors Influencing the Nitrogen-Source Dependent Flucytosine Resistance in Cryptococcus Species
mBio·2023· 9 citedOpen Access
S7.4a Vaccine-inducing lung resident CD4 + memory T cells are protective against <i>Cryptococcus gattii</i> infections
Medical Mycology·2022Open Access
MDA5 signaling induces type 1 IFN- and IL-1-dependent lung vascular permeability which protects mice from opportunistic fungal infection
Frontiers in Immunology·2022· 4 citedOpen Access
Cryptococcus gattii Species Complex as an Opportunistic Pathogen: Underlying Medical Conditions Associated with the Infection
mBio·2021· 45 citedOpen Access
Novel angular naphthopyrone formation by Arp1p dehydratase involved in <i>Aspergillus fumigatus</i> melanin biosynthesis
Environmental Microbiology Reports·2021· 7 citedOpen Access
<i>In Vivo</i> Efficacy of Olorofim against Systemic Scedosporiosis and Lomentosporiosis
Antimicrobial Agents and Chemotherapy·2021· 42 citedOpen Access
Moderate levels of 5-fluorocytosine cause the emergence of high frequency resistance in cryptococci
Nature Communications·2021· 45 citedOpen Access
Antifungal Susceptibility Profiles of Olorofim (Formerly F901318) and Currently Available Systemic Antifungals against Mold and Yeast Phases of <i>Talaromyces marneffei</i>
Antimicrobial Agents and Chemotherapy·2021· 30 citedOpen Access
Type I IFN induces vascular permeability delivering iron binding proteins to the site of <i>Cryptococcosis gattii</i> infection resulting in local nutritional immunity and contained infection
The Journal of Immunology·2020
Regions of mouse chromosomes 2 and 11 in SJL mice contain critical alleles for resistance to <i>Cryptococcus neoformans</i>
The Journal of Immunology·2020
A New Lineage of Cryptococcus gattii (VGV) Discovered in the Central Zambezian Miombo Woodlands
mBio·2019· 90 citedOpen Access
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Frequent Co-authors

Kyung J. Kwon‐Chung(25), Kyung J. Kwon‐Chung(17), Janyce A. Sugui(7), Ambrose Jong(7), Edward Sionov(6), Huei‐Fung Tsai(6), Hyeseung Lee(5), K. J. Kwon-Chung(5), Sheng‐He Huang(5), Chunhua Wu(5), Brian L. Wickes(4), Kol A. Zarember(4), John I. Gallin(4), Steven M. Holland(3), Michael H. Wheeler(3), Georgina Miller(3), Glenn Nardone(3), L. Penoyer(3), Clara M. Bien(3), Peter J. Espenshade(3)