Csilla Özvegy‐Laczka

Institute of Materials and Environmental Chemistry — Hungary

Medicine · Health Sciences

33h-index4.2kcitations81works2.42yr avg
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Research Topics

Drug Transport and Resistance Mechanisms(70), Pharmacological Effects and Toxicity Studies(21), Metal complexes synthesis and properties(12), HIV/AIDS drug development and treatment(12), Trace Elements in Health(11)

Publications81 total

<i>In Vitro</i> Evaluation of the Potential Interactions of Zearalenone-14-sulfate and Zearalenone-14-glucuronide with Human Cytochrome P450 Enzymes, Organic Anion Transporting Polypeptides, and ATP-Binding Cassette Multidrug Transporters
ACS Omega·2025Open Access
Comparative study of multidrug resistance-targeting 8-hydroxyquinoline-amino acid conjugates: anticancer effect, interaction with human serum albumin and organic anion transporting polypeptides
European Journal of Pharmaceutical Sciences·2025· 2 citedOpen Access
Cancer-type OATP1B3-V1 is a functional plasma membrane transporter mediating increased uptake of chemotherapeutics in vitro and in vivo
European Journal of Pharmaceutical Sciences·2025Open Access
Facile Synthesis of Pyridyl Rosamines as Potential Photosensitizers
International Journal of Molecular Sciences·2025· 1 citedOpen Access
Functional and structural polypharmacology of indazole-based privileged ligands to tackle the undruggability of membrane transporters
European Journal of Medicinal Chemistry·2025· 6 citedOpen Access
Interaction of myricetin, ampelopsin (dihydromyricetin), and their sulfate metabolites with serum albumin, cytochrome <scp>P450</scp> (<scp>CYP2C9</scp>, <scp>2C19</scp>, and <scp>3A4</scp>) enzymes, and organic anion‐transporting polypeptides (<scp>OATP1B1</scp> and <scp>OATP2B1</scp>)
Pharmacology Research & Perspectives·2024· 2 citedOpen Access
Synthesis and estrogenic activity of BODIPY-labeled estradiol conjugates
European Journal of Pharmaceutical Sciences·2024· 3 citedOpen Access
The 2-aminoethyl diphenylborinate-based fluorescent method identifies quercetin and luteolin metabolites as substrates of Organic anion transporting polypeptides, OATP1B1 and OATP2B1
European Journal of Pharmaceutical Sciences·2024· 3 citedOpen Access
Interaction of mycotoxins zearalenone, α-zearalenol, and β-zearalenol with cytochrome P450 (CYP1A2, 2C9, 2C19, 2D6, and 3A4) enzymes and organic anion transporting polypeptides (OATP1A2, OATP1B1, OATP1B3, and OATP2B1)
Toxicology in Vitro·2024· 6 citedOpen Access
Interactions of anti-COVID-19 drug candidates with hepatic transporters may cause liver toxicity and affect drug metabolism
2024· 1 citedOpen Access
The fluorescence‐based competitive counterflow assay developed for organic anion transporting polypeptides <scp>1A2</scp> , <scp>1B1</scp> , <scp>1B3</scp> and <scp>2B1</scp> identifies pentamidine as a selective <scp>OATP1A2</scp> substrate
The FASEB Journal·2023· 6 citedOpen Access
Interactions of the Anti-SARS-CoV-2 Agents Molnupiravir and Nirmatrelvir/Paxlovid with Human Drug Transporters
International Journal of Molecular Sciences·2023· 6 citedOpen Access
Organic Anion Transporting Polypeptide 3A1 (OATP3A1)-Gated Bio-Orthogonal Labeling of Intracellular Proteins
Molecules·2023Open Access
Fluorescence-based methods for studying activity and drug-drug interactions of hepatic solute carrier and ATP binding cassette proteins involved in ADME-Tox
Biochemical Pharmacology·2023· 15 citedOpen Access
Synthesis and <i>in vitro</i> photodynamic activity of aza-BODIPY-based photosensitizers
Organic & Biomolecular Chemistry·2023· 9 citedOpen Access
Metal Complexes of a 5-Nitro-8-Hydroxyquinoline-Proline Hybrid with Enhanced Water Solubility Targeting Multidrug Resistant Cancer Cells
International Journal of Molecular Sciences·2022· 22 citedOpen Access
Interactions of Mycotoxin Alternariol with Cytochrome P450 Enzymes and OATP Transporters
Metabolites·2022· 8 citedOpen Access
Interaction of luteolin, naringenin, and their sulfate and glucuronide conjugates with human serum albumin, cytochrome P450 (CYP2C9, CYP2C19, and CYP3A4) enzymes and organic anion transporting polypeptide (OATP1B1 and OATP2B1) transporters
Biomedicine & Pharmacotherapy·2022· 31 citedOpen Access
Editorial: Women in experimental pharmacology and drug discovery: 2021
Frontiers in Pharmacology·2022Open Access
Cloning and characterization of a novel functional organic anion transporting polypeptide 3A1 isoform highly expressed in the human brain and testis
Frontiers in Pharmacology·2022· 10 citedOpen Access
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Frequent Co-authors

Balázs Sarkadi(30), András Váradi(17), Gergely Szakács(16), Ágnes Telbisz(11), Éva Bakos(11), György Várady(10), Csilla Hegedüs(9), Izabel Patik(8), Katalin Német(7), N. Barry Elkind(5), Orsolya Ungvári(5), Gÿorgý Kéri(4), László Homolya(4), Tamás Hegedűs(4), Eszter Fliszár-Nyúl(4), Miklós Poór(4), Virág Székely(4), Orsolya Német(4), Olga Ujhelly(3), László Őrfi(3)