Xumu Zhang

Tianjin University — China

Chemistry · Physical Sciences

86h-index29.3kcitations751works4.12yr avg
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Research Topics

Asymmetric Hydrogenation and Catalysis(582), Asymmetric Synthesis and Catalysis(264), Surface Chemistry and Catalysis(204), Chemical Synthesis and Analysis(131), Catalytic C–H Functionalization Methods(87)

Publications748 total

Redox-Free and Modular Access to Oxacyclic Phosphines Enabled by a Robust Ambiphilic Phosphine Reagent
CCS Chemistry·2025· 1 citedOpen Access
Ligand-based design and optimization of tecovirimat derivatives as potent antiviral agents against monkeypox virus
European Journal of Medicinal Chemistry·2025
Enantioselective total synthesis of 3-deoxy-epothilone B enabled by efficient asymmetric catalysis
Chinese Chemical Letters·2025
Development of an Optimized Synthetic Process for Onradivir Featuring a “One-Pot” Miyaura–Suzuki Coupling Reaction
Organic Process Research & Development·2025· 1 cited
Amine–Borane-Promoted Rhodium-Catalyzed Asymmetric Transfer Hydrogenation of β-Chloro Ketones
Organic Letters·2025· 2 cited
Preclinical characterization and anti-RSV efficacy of an oral C-nucleoside derivative
Acta Pharmaceutica Sinica B·2025Open Access
Identification and Evaluation of Non-Nucleosidic MTase Inhibitors against SARS-CoV-2 nsp14 with Lower-Micromolar Anti-Coronavirus Activity
ACS Infectious Diseases·2025· 4 cited
Rationally Designed Fe-Cyclopentadienone with Unique Orientations for Efficient Asymmetric Hydrogenation of Acylsilanes
2025Open Access
π-π interaction-directed asymmetric hydrogenation of sterically unbiased aromatic ketones
Chem Catalysis·2025
Catalytic Intramolecular Reductive Amination Using Secondary Amines: Expanding Access to Chiral Tertiary Amine Heterocycles
Organic Letters·2025· 2 cited
Development of Multidentate P,P,N,N-Ligands for Ruthenium-Catalyzed Enantioselective Hydrogenation of 2-Pyridyl Ketones
The Journal of Organic Chemistry·2025· 2 cited
Access to Terminal Alkynes via Palladium-Catalyzed Coupling of ArCl with a Low Catalyst Loading of 0.08 mol %
The Journal of Organic Chemistry·2025
Asymmetric Hydrogenation of β-Azaaryl α,β-Unsaturated Nitriles: An Access to Ruxolitinib
Organic Letters·2025· 3 cited
Highly Enantioselective Formal Synthesis of (+)‐Treprostinil Enabled by Rhodium‐Catalyzed Enyne Cycloisomerization
Chinese Journal of Chemistry·2025· 3 cited
Mini review: SHEN26, a novel oral antiviral drug for COVID-19 treatment
Bioorganic & Medicinal Chemistry Letters·2025· 1 cited
Broad‐Spectrum Antiviral Activity of the Orally Bioavailable Antiviral ATV014 Against Multiple Coronaviruses
MedComm·2025Open Access
Stereoselective Nickel-Catalyzed Iterative 1,2-Reduction of Trisubstituted Enones to Cycloalkanols Bearing Two Contiguous Stereocenters
Organic Letters·2025· 4 cited
Anti-SARS-CoV-2 prodrug ATV006 has broad-spectrum antiviral activity against human and animal coronaviruses
Acta Pharmaceutica Sinica B·2025· 3 citedOpen Access
Catalytic Regio- and Enantioselective Hydroformylation of Trisubstituted Alkenes to Construct α-Quaternary Lactams
Journal of the American Chemical Society·2025· 10 cited
Efficacy and safety of SHEN26, a novel oral small molecular RdRp inhibitor for COVID-19 treatment: a multicenter, randomized, double-blinded, placebo-controlled, phase II clinical trial
Virology Journal·2025· 1 citedOpen Access
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Frequent Co-authors

Wenjun Tang(6), Dengming Xiao(5), Qiongzhong Jiang(4), Jialin Wen(4), Zhaoguo Zhang(4), Wenzhong Gao(4), James M. Longmire(3), Guoxin Zhu(3), Yongxiang Chi(3), Yong‐Gui Zhou(3), Qin Yin(3), Qin Yang(3), Shang Gao(3), Duan Liu(3), Qingyang Zhao(3), Zhaogen Chen(2), Ping Cao(2), Zheng Wang(2), Kuiling Ding(2), Yutong Jiang(2)