Lira Mamanova

Wellcome Sanger Institute — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

35h-index9.7kcitations88works15.72yr avg
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Research Topics

Single-cell and spatial transcriptomics(33), Immune Cell Function and Interaction(12), T-cell and B-cell Immunology(11), Cancer Genomics and Diagnostics(11), IL-33, ST2, and ILC Pathways(10)

Publications88 total

Multimodal profiling reveals tissue-directed signatures of human immune cells altered with age
Nature Immunology·2025· 13 citedOpen Access
Single-cell transcriptomics identifies chondrocyte differentiation dynamics in vivo and in vitro
Developmental Cell·2025· 4 citedOpen Access
Single cell transcriptional evolution of myeloid leukaemia of Down syndrome
2025· 1 cited
Author Correction: Spatially resolved multiomics of human cardiac niches
Nature·2025· 2 citedOpen Access
HOX gene expression in the developing human spine
Nature Communications·2024· 16 citedOpen Access
Early human lung immune cell development and its role in epithelial cell fate
2024
Human SARS-CoV-2 challenge uncovers differences in local and systemic cellular responses associated with protection from infection and distinct infection states
2024
Author Correction: Human SARS-CoV-2 challenge uncovers local and systemic response dynamics
Nature·2024· 2 citedOpen Access
Human SARS-CoV-2 challenge uncovers local and systemic response dynamics
Nature·2024· 103 citedOpen Access
Author Correction: Age-specific nasal epithelial responses to SARS-CoV-2 infection
Nature Microbiology·2024· 1 citedOpen Access
Early Human Lung Immune Cell Development and Its Role in Epithelial Cell Fate
2024
Age-specific nasal epithelial responses to SARS-CoV-2 infection
Nature Microbiology·2024· 43 citedOpen Access
Multimodal profiling reveals tissue-directed signatures of human immune cells altered with age
2024· 19 citedOpen Access
Single cell transcriptomics reveals chondrocyte differentiation dynamics <i>in vivo</i> and <i>in vitro</i>
2023· 4 citedOpen Access
Early human lung immune cell development and its role in epithelial cell fate
Science Immunology·2023· 85 citedOpen Access
A human embryonic limb cell atlas resolved in space and time
Nature·2023· 108 citedOpen Access
Systematic benchmarking of single-cell ATAC-sequencing protocols
Nature Biotechnology·2023· 46 citedOpen Access
Spatially resolved multiomics of human cardiac niches
Nature·2023· 325 citedOpen Access
Human SARS-CoV-2 challenge resolves local and systemic response dynamics
2023· 14 citedOpen Access
Longitudinal blood and tissue single cell transcriptomics of humans challenged with SARS-CoV-2 reveals innate and adaptive immune dynamics
10.01 - Respiratory infections and bronchiectasis·2023
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Frequent Co-authors

Sarah A. Teichmann(35), Krzysztof Polański(25), Liam Bolt(23), Kerstin B. Meyer(21), Muzlifah Haniffa(16), Menna R. Clatworthy(15), Anna Wilbrey-Clark(15), Sam Behjati(12), Cecilia Domínguez Conde(10), Krishnaa T. Mahbubani(10), Elizabeth Tuck(10), Omer Ali Bayraktar(10), Matthew D. Young(10), Xiaoling He(10), Roger A. Barker(10), Masahiro Yoshida(10), J. Patrick Pett(10), Ni Huang(9), Rasa Elmentaite(9), Kourosh Saeb‐Parsy(9)