Florian Müllershausen

Novartis (Switzerland) — Switzerland

Medicine · Health Sciences

16h-index1.9kcitations28works0.02yr avg
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Research Topics

Nitric Oxide and Endothelin Effects(19), Phosphodiesterase function and regulation(11), Sphingolipid Metabolism and Signaling(8), Receptor Mechanisms and Signaling(6), Renin-Angiotensin System Studies(5)

Publications28 total

Tesidolumab (LFG316) for treatment of C5-variant patients with paroxysmal nocturnal hemoglobinuria
Haematologica·2022· 12 citedOpen Access
Investigating the molecular mechanisms through which <scp>FTY</scp>720‐<scp>P</scp> causes persistent <scp>S1P<sub>1</sub></scp> receptor internalization
British Journal of Pharmacology·2014· 73 citedOpen Access
Pathway specific modulation of <scp>S1P1</scp> receptor signalling in rat and human astrocytes
British Journal of Pharmacology·2013· 46 citedOpen Access
Erratum: Corrigendum: Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors
Nature Chemical Biology·2009· 12 citedOpen Access
Exogenous Nitric Oxide Donation Causes Desensitization of Arteriolar Relaxing Activity In Vivo: An Intravital Analysis in Mice
Journal of Surgical Research·2009· 10 cited
Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors
Nature Chemical Biology·2009· 365 cited
Design of fluorescence resonance energy transfer (FRET)-based cGMP indicators: a systematic approach
Biochemical Journal·2007· 149 citedOpen Access
Brain sphingosine-1-phosphate receptors: Implication for FTY720 in the treatment of multiple sclerosis
Pharmacology & Therapeutics·2007· 154 cited
Phosphorylated FTY720 promotes astrocyte migration through sphingosine‐1‐phosphate receptors
Journal of Neurochemistry·2007· 141 cited
Design and characterization of FRET-based cGMP indicators
BMC Pharmacology·2007Open Access
Phosphorylated FTY720 promotes astrocyte migration through sphingosine-1-phosphate receptors
Journal of Neurochemistry·2007· 6 cited
Phosphorylated FTY720 stimulates ERK phosphorylation in astrocytes via S1P receptors
Neuropharmacology·2007· 113 cited
Desensitization of NO/cGMP Signaling in Smooth Muscle: Blood Vessels Versus Airways
Molecular Pharmacology·2006· 37 cited
Negative feedback in NO/cGMP signalling
Biochemical Society Transactions·2005· 12 cited
Negative feedback in NO/cGMP signalling
Biochemical Society Transactions·2005· 21 cited
Desensitisation of NO/cGMP signalling in vascular and bronchial smooth muscle
BMC Pharmacology·2005Open Access
NO/cGMP signalling
BMC Pharmacology·2005Open Access
In Vivo Reconstitution of the Negative Feedback in Nitric Oxide/cGMP Signaling: Role of Phosphodiesterase Type 5 Phosphorylation
Molecular Biology of the Cell·2004· 41 citedOpen Access
Nitric oxide-sensitive guanylyl cyclase: structure and regulation
Neurochemistry International·2004· 148 cited
Inhibition of Phosphodiesterase Type 5 by the Activator of Nitric Oxide–Sensitive Guanylyl Cyclase BAY 41-2272
Circulation·2004· 68 cited
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Frequent Co-authors

Doris Koesling(19), Andreas Friebe(17), Michael Russwurm(13), Danilo Guerini(5), Kumlesh K. Dev(5), Evanthia Mergia(5), Alexander Lange(5), Klaus Seuwen(4), Maribel Osinde(3), Corina Wagner(3), Frédéric J. Zécri(2), Cihan Cetin(2), Andreas Billich(2), William J. Thompson(2), Ronald Jäger(2), Corina Russwurm(2), Luis M. Craveiro(2), Youngah Shin(2), Marta Cortés-Cros(2), Frédéric Bassilana(2)