Alan C. Mullen

Broad Institute — United States

Medicine · Health Sciences

28h-index9.2kcitations82works5.12yr avg
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Research Topics

Liver Disease Diagnosis and Treatment(31), Cancer-related molecular mechanisms research(13), RNA modifications and cancer(13), T-cell and B-cell Immunology(12), Immune Cell Function and Interaction(11)

Publications82 total

Prime Editing Models the MTARC1 A165T Variant in Human Liver Organoids, Demonstrating Reduced Steatosis, Inflammation, and Fibrosis
2025Open Access
Author Correction: Towards a reference cell atlas of liver diversity over the human lifespan
Nature Reviews Gastroenterology & Hepatology·2025Open Access
Towards a reference cell atlas of liver diversity over the human lifespan
Nature Reviews Gastroenterology & Hepatology·2025
Durotaxis is a driver and potential therapeutic target in lung fibrosis and metastatic pancreatic cancer
Nature Cell Biology·2025· 9 citedOpen Access
Singletrome enhances detection of long noncoding RNAs in single cell transcriptomes
Scientific Reports·2025· 4 citedOpen Access
UCP1 Mitigates Hepatic Steatosis and Fibrosis Independent of Cold Exposure
2025Open Access
Discovery of Clonixeril as a Sub-Femtomolar Modulator of the Human STING Receptor
ACS Central Science·2025Open Access
Suppression of HIV-1 transcription and latency reversal via ectopic expression of the viral antisense transcript AST
Science Advances·2025· 6 citedOpen Access
Function Over Form: Defining Evolutionarily Conserved Long Noncoding RNAs Regulating Hepatic Metabolism
Gastroenterology·2025
Screening the human druggable genome identifies ABHD17B as an anti-fibrotic target in hepatic stellate cells
Nature Communications·2025· 2 citedOpen Access
Single-cell transcriptomics reveals the impact of sex and age in the healthy human liver
2025Open Access
Discovery of Clonixeril as a Sub-Femtomolar Modulator of the Human STING Receptor
2025Open Access
Spatial transcriptomics of healthy and fibrotic human liver at single-cell resolution
Nature Communications·2025· 55 citedOpen Access
Epigenetic silencing and blockade of latency reversal by an HIV-1 encoded antisense transcript
2024Open Access
Author Correction: Single‐cell transcriptomics stratifies organoid models of metabolic dysfunction‐associated steatotic liver disease
The EMBO Journal·2024· 1 citedOpen Access
Discovery of Clonixeril as a Sub-Femtomolar Modulator of the Human STING Receptor
2024Open Access
Discovery of Clonixeril as a Sub-Femtomolar Modulator of the Human STING Receptor
2024· 1 citedOpen Access
Author Correction: IFNγ-IL12 axis regulates intercellular crosstalk in metabolic dysfunction-associated steatotic liver disease
Nature Communications·2024Open Access
IFNγ-IL12 axis regulates intercellular crosstalk in metabolic dysfunction-associated steatotic liver disease
Nature Communications·2024· 17 citedOpen Access
Conserved long noncoding RNA TILAM promotes liver fibrosis through interaction with PML in HSCs
Hepatology·2024· 7 citedOpen Access
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Frequent Co-authors

Chan Zhou(15), K. Daneshvar(12), Joshua V. Pondick(11), Raza‐Ur Rahman(11), Steven L. Reiner(10), Robert P. Sparks(10), Sean P. Moran(8), Anne S. Hutchins(7), Amel Ben Saad(7), Lorena Pantano(6), Benoit Molinié(5), Cosmas Giallourakis(5), Frances A. High(5), Hubert W. Lee(5), Raymond T. Chung(5), Jennifer Y. Chen(5), Samuel York(5), Shannan J. Ho Sui(5), Zixiu Li(5), Wenyang Li(5)