Gilbert Schlewer

Centre National de la Recherche Scientifique — France

Agricultural and Biological Sciences · Life Sciences

16h-index1.1kcitations97works0.02yr avg
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Research Topics

Phytase and its Applications(26), Protein Kinase Regulation and GTPase Signaling(22), Carbohydrate Chemistry and Synthesis(16), Trace Elements in Health(12), Phenothiazines and Benzothiazines Synthesis and Activities(9)

Publications97 total

Synthesis of (±)-2-<i>O</i>-[4‘-(<i>N</i>-9‘ ‘-Purinyl)butyl] <i>myo</i>-Inositol 1,4,5-Tris(phosphate), a Potent Full Agonist at the <scp>d</scp>-<i>myo</i>-Inositol 1,4,5-Tris(phosphate) Receptor
Journal of Medicinal Chemistry·2005· 8 citedOpen Access
Synthesis of (°)(2-O-[4'-(N-9“-purinyl)butyl] myo-Inositol 1,4,5-Tris(phosphate), a potent full agonist at the D-myo-inositol 1,4,5-Tris(phosphate) receptor.
HAL (Le Centre pour la Communication Scientifique Directe)·2005
Syntheses and GABA Uptake Properties of 6‐Ether‐ and 6‐Enol Ether‐Substituted Nipecotic Acids.
ChemInform·2004
Synthesis and GABA uptake inhibitory properties of 6-aryl iminoxymethyl substituted nipecotic acids
European Journal of Medicinal Chemistry·2004· 12 cited
Synthesis and binding properties of cyclopentane analogues of myo-inositol 1,4,5-tris(phosphate)
Bioorganic & Medicinal Chemistry·2004· 3 cited
Syntheses and GABA uptake properties of 6-ether- and 6-enol ether-substituted nipecotic acids
European Journal of Medicinal Chemistry·2004· 6 cited
Syntheses and GABA uptake properties of 6-ether- and 6 enolether-substituted nipecotic acids
HAL (Le Centre pour la Communication Scientifique Directe)·2004
Inframolecular acid–base studies of the tris and tetrakis myo-inositol phosphates including the 1,2,3-trisphosphate motif
Journal of Molecular Structure·2002· 16 cited
<i>myo</i>-Inositol 1,4,5,6-Tetrakisphosphate and <i>myo</i>-Inositol 3,4,5,6-Tetrakisphosphate, Two Second Messengers that May Act as pH-Dependent Molecular Switches  [<i>J. Am. Chem. Soc.</i> <b>2001</b>, <i>123</i>, 3399−4000].
Journal of the American Chemical Society·2001· 1 cited
Inframolecular Protonation Process of <i>myo</i>-Inositol 1,4,5-Tris(phosphate) and Related Compounds:  Dynamics of the Intramolecular Interactions and Evidence of C−H···O Hydrogen Bonding
Journal of the American Chemical Society·2000· 39 cited
Inframolecular protonation process of 6-modified myo-inositol 1,4,5-tris(phosphates): substitution effects on the cooperativity between the phosphate groups
New Journal of Chemistry·2000· 13 cited
Inframolecular studies of the protonation of 1d-1,2,4/3,5-cyclopentanepentaol 1,3,4-trisphosphate, a ring-contracted analogue of 1d-myo-inositol 1,4,5-trisphosphate
Carbohydrate Research·1999· 5 cited
Synthesis, Acid−Base Behavior, and Binding Properties of 6-Modified <i>myo</i>-Inositol 1,4,5-Tris(phosphate)s
Journal of Medicinal Chemistry·1999· 19 citedOpen Access
Inositol Phosphates: Inframolecular Physico-Chemical Studies: Correlation with Binding Properties
ACS symposium series·1998· 6 cited
ChemInform Abstract: Synthesis of myo‐Inositol 4,6‐cyclic,1,5‐Trisphosphate, a Conformationally Restricted Analogue of myo‐Inositol 1,4,5‐Trisphosphate.
ChemInform·1998
ChemInform Abstract: Synthesis of 1‐O‐(2‐Oxo‐benzo‐1,3,2‐dioxaphosphaocan‐2‐yl)‐myo‐inositol and 3,5‐Dideoxy‐1‐O‐(2‐oxo‐benzo‐1,3,2‐dioxaphosphaocan‐2‐yl)‐myo‐inositol as Prodrugs of Inositolmonophosphatase Ligands.
ChemInform·1998
ChemInform Abstract: Synthesis of Arylalkylmonofluorophosphonates as myo‐Inositol Monophosphatase Ligands.
ChemInform·1998
Synthesis of 1-O-(2-oxo-benzo-1,3,2-dioxaphosphaocan-2-yl)-myo-inositol and 3,5-dideoxy-1-O-(2-oxo-benzo-1,3,2-dioxaphosphaocan-2-yl)-myo-inositol as prodrugs of inositolmonophosphatase ligands
Tetrahedron Letters·1998· 6 cited
ChemInform Abstract: A Conformationally Restricted Cyclic Phosphate Analogue of Inositol Trisphosphate: Synthesis and Physicochemical Properties.
ChemInform·1998
ChemInform Abstract: C‐ or O‐Alkylation of 5‐Ethoxycarbonyl‐2‐hydroxymethyl Pyridine with Arylmethane Derivatives.
ChemInform·1998
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Frequent Co-authors

Bernard Spiess(29), Laurent Schmitt(10), Camille G. Wermuth(8), Philippe Guédat(8), Claude Benezra(7), Khalid Mernissi-Arifi(6), Jean‐Luc Stampf(6), Stéphanie Ballereau(5), Victor N’Goka(4), Gaétan Guillemette(4), Anita Melikian(3), Nicola Rehnberg(3), Povl Krogsgaard‐Larsen(3), Jean Bourguignon(2), Jean Pierre Gies(2), Marie Jeanne Bouchet(2), Jean Pierre Chambon(2), Kathleen Bizière(2), J Foussereau(2), Andrew M. Riley(2)