Reinhard Klement

Max Planck Institute of Biophysics — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index562citations28works0.32yr avg
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Research Topics

DNA and Nucleic Acid Chemistry(13), Advanced biosensing and bioanalysis techniques(8), Parkinson's Disease Mechanisms and Treatments(7), RNA Interference and Gene Delivery(6), Protein Structure and Dynamics(3)

Publications28 total

Hierarchically ordered multi-timescale structural dynamics of the intrinsically disordered p53 transactivation domain
2025· 1 citedOpen Access
Hierarchically ordered multi-timescale structural dynamics of the intrinsically disordered p53 transactivation domain
Max Planck Digital Library·2025Open Access
BPS2025 - Structured disorder: Hierarchical dynamics of the p53 transactivation domain
Biophysical Journal·2025
Spatiotemporal Resolution of Conformational Changes in Biomolecules by Combining Pulsed Electron–Electron Double Resonance Spectroscopy with Microsecond Freeze-Hyperquenching
Journal of the American Chemical Society·2021· 44 citedOpen Access
Transient Structure Formation Kinetics of Monomeric Alpha-Synuclein Derived from MD Simulations
Biophysical Journal·2020Open Access
Transient Secondary and Tertiary Structure Formation Kinetics in the Intrinsically Disordered State of <i>α</i>‐Synuclein from Atomistic Simulations
ChemPhysChem·2018· 23 citedOpen Access
Structural Dynamics of Monomeric α-Synuclein on the PS-µS Time Scale Derived from MD Simulations
Biophysical Journal·2018Open Access
Molecular Dynamics Simulations of Alpha-Synuclein Ensemble FRET Measurements from Different Force Fields
Biophysical Journal·2016· 3 citedOpen Access
Intrinsically Disordered Proteins (IDP) and Aggregates: Ab, Tau, and a-Synuclein
2016
Local Dynamics of FRET Dyes in an Intrinsically Disordered Protein Studied by MD Simulations
Biophysical Journal·2014Open Access
Dynamic conformational transitions of the EGF receptor in living mammalian cells determined by FRET and fluorescence lifetime imaging microscopy
Cytometry Part A·2013· 50 citedOpen Access
α-Synuclein Monomer Conformations Studied by in Silico and in Vitro FRET
Biophysical Journal·2012Open Access
Fluorescence imaging of amyloid formation in living cells by a functional, tetracysteine-tagged α-synuclein
Nature Methods·2007· 129 cited
Crystal and solution structures of 7-amino-actinomycin D complexes with d(TTAGBrUT), d(TTAGTT) and d(TTTAGTTT)
Acta Crystallographica Section D Biological Crystallography·2005· 15 citedOpen Access
The snRNP 15.5K protein folds its cognate K-turn RNA: A combined theoretical and biochemical study
RNA·2005· 42 citedOpen Access
Parallel DNA double helices incorporating isoG or m5isoC bases studied by FTIR, CD and molecular modeling
Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy·2004· 10 cited
Crystal structure of 7-Aminoactinomycin D with non-complementary DNA
2003
The Telomeric dG(GT) <sub>4</sub> G Sequence Can Adopt a Parallel-Stranded Double Helical Conformation
Journal of Biomolecular Structure and Dynamics·2001· 7 citedOpen Access
Parallel-Stranded DNA with Mixed AT/GC Composition:  Role of trans G·C Base Pairs in Sequence Dependent Helical Stability
Biochemistry·2000· 32 cited
Parallel-stranded duplex DNA containing dA · dU base pairs
Biopolymers·1998· 14 cited
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Frequent Co-authors

Thomas M. Jovin(13), Helmut Grubmüller(6), Elisha Haas(6), Elizabeth A. Jares‐Erijman(5), Anna K. Shchyolkina(5), Timo Graen(5), Asaf Grupi(5), Dániel Szöllősi(3), Supriya Pratihar(3), Dwaipayan Mukhopadhyay(3), Sarah Rauscher(3), Christian Griesinger(3), Helmut Grubmueller(3), Randy M. Wadkins(2), Thomas M. Jovin(2), Olga F. Borisova(2), Michael A. Livshits(2), J. Liquier(2), E. Taillandier(2), E. Alexopoulos(2)