Urs A. Ochsner

Crestone (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

52h-index13.2kcitations97works0.02yr avg
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Research Topics

Bacterial Genetics and Biotechnology(36), Bacterial biofilms and quorum sensing(22), Tuberculosis Research and Epidemiology(16), RNA and protein synthesis mechanisms(14), Antibiotic Resistance in Bacteria(10)

Publications97 total

Safety and efficacy of CRS3123 in adults with a primary episode or first recurrence of Clostridioides difficile infection: a phase 2, randomised, double-blind, multicentre, vancomycin-controlled study
The Lancet Infectious Diseases·2026Open Access
Microbiological profile, preclinical pharmacokinetics and efficacy of CRS0393, a novel antimycobacterial agent targeting MmpL3
Tuberculosis·2022· 9 citedOpen Access
Potency of the novel PolC DNA polymerase inhibitor CRS0540 in a disseminated <i>Listeria monocytogenes</i> intracellular hollow-fibre model
Journal of Antimicrobial Chemotherapy·2022· 4 citedOpen Access
IL‐10 induces IgG4 production in NOD‐<i>scid</i> Il2rγ<sup>null</sup> mice humanized by engraftment of peripheral blood mononuclear cells
Allergy·2021· 10 citedOpen Access
A novel proangiogenic B cell subset is increased in cancer and chronic inflammation
Science Advances·2020· 66 citedOpen Access
Multiple-Ascending-Dose Phase 1 Clinical Study of the Safety, Tolerability, and Pharmacokinetics of CRS3123, a Narrow-Spectrum Agent with Minimal Disruption of Normal Gut Microbiota
Antimicrobial Agents and Chemotherapy·2019· 35 citedOpen Access
Targeting Unique Epitopes on Highly Similar Proteins GDF-11 and GDF-8 with Modified DNA Aptamers
Biochemistry·2019· 13 cited
Correction: Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study
PLoS Medicine·2019· 7 citedOpen Access
Discovery and validation of a prognostic proteomic signature for tuberculosis progression: A prospective cohort study
PLoS Medicine·2019· 95 citedOpen Access
Comparison of regulatory B cells in asthma and allergic rhinitis
Allergy·2018· 31 citedOpen Access
Optimization and Lead Selection of Benzothiazole Amide Analogs Toward a Novel Antimycobacterial Agent
Frontiers in Microbiology·2018· 33 citedOpen Access
Discovery of benzothiazole amides as potent antimycobacterial agents
Bioorganic & Medicinal Chemistry Letters·2018· 32 citedOpen Access
Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease
PLoS Pathogens·2017· 241 citedOpen Access
Potential of High-Affinity, Slow Off-Rate Modified Aptamer Reagents for Mycobacterium tuberculosis Proteins as Tools for Infection Models and Diagnostic Applications
Journal of Clinical Microbiology·2017· 35 citedOpen Access
Discovery and Validation of a Six-Marker Serum Protein Signature for the Diagnosis of Active Pulmonary Tuberculosis
Journal of Clinical Microbiology·2017· 94 citedOpen Access
Safety, Tolerability, Systemic Exposure, and Metabolism of CRS3123, a Methionyl-tRNA Synthetase Inhibitor Developed for Treatment of Clostridium difficile, in a Phase 1 Study
Antimicrobial Agents and Chemotherapy·2017· 48 citedOpen Access
Correction for De Groote et al., “Highly Multiplexed Proteomic Analysis of Quantiferon Supernatants To Identify Biomarkers of Latent Tuberculosis Infection”
Journal of Clinical Microbiology·2017Open Access
Highly Multiplexed Proteomic Analysis of Quantiferon Supernatants To Identify Biomarkers of Latent Tuberculosis Infection
Journal of Clinical Microbiology·2016· 46 citedOpen Access
A novel, dual cytokine‐secretion assay for the purification of human Th22 cells that do not co‐produce <scp>IL</scp>‐17A
Allergy·2015· 13 cited
Biomarkers for progression from latent to active tuberculosis identified in multiplexed proteomic assay (SOMAscan™) of human plasma (MPF6P.657)
The Journal of Immunology·2015
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Frequent Co-authors

Michael L. Vasil(19), Daniel J. Hassett(12), Nebojša Janjić(11), Zaiga Johnson(7), Mary Ann De Groote(6), Thale C. Jarvis(5), Michelle S. Parvatiyar(5), Adriana I. Vasil(5), Michael J. Howell(5), Timothy R. McDermott(4), Jakob Reiser(4), Eyad Alsabbagh(4), Pierre Cornélis(4), Ian A. Critchley(4), Larry Gold(3), Stephan Kräemer(3), Rachel Ostroff(3), John C. Rohloff(3), A. Fiechter(3), John L. Johnson(3)