Khalid Saeed

University of Helsinki — Finland

Immunology and Microbiology · Life Sciences

9h-index548citations53works2.52yr avg
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Research Topics

Immune Cell Function and Interaction(14), CRISPR and Genetic Engineering(7), Cancer Genomics and Diagnostics(7), Single-cell and spatial transcriptomics(5), CAR-T cell therapy research(5)

Publications53 total

ACE Inhibitors Boost Mobility and Muscle Strength by Reducing Intestinal Permeability in Older Adults with Alzheimer’s Disease
Pharmaceuticals·2026Open Access
Artificial Intelligence in Clinical Trials: From Protocol Design to Pharmacovigilance
2026
Data-driven strategies for drug repurposing: insights, recommendations, and case studies
Briefings in Bioinformatics·2025· 2 citedOpen Access
DLRNA-BERTa: A transformer approach for RNA-drug binding affinity prediction
2025Open Access
Data-driven strategies for drug repurposing: insights, recommendations, and case studies
2025· 1 citedOpen Access
Catestatin alleviates PASMC phenotypic switching-mediated pulmonary arterial remodeling in a rat model of MCT-induced pulmonary arterial hypertension by promoting endothelium-derived no synthesis
Nitric Oxide·2025
Direct Oral Anticoagulants Are Comparable to Low Molecular Weight Heparin at Sustaining the Circulating Extracellular Vesicle and Inflammatory Profiles of Cancer Associated Thrombosis Patients: An Observational Pilot Study
Cancer Medicine·2025· 3 citedOpen Access
A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency
BMC Genomics·2025· 9 citedOpen Access
High-throughput drug screening identifies SMAC mimetics as enhancers of NK-cell cytotoxicity in chronic myeloid leukemia
Blood·2025· 3 citedOpen Access
Increasing clinical recruitment rate to a single-site observational study: a quality improvement study
BMJ Open Quality·2025Open Access
Comprehensive Drug Profiling and CRISPR Screening Reveal Essential Pathways for NK Cell Cytotoxicity
Blood·2024Open Access
A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency
2024· 1 citedOpen Access
Abstract 2945: Using pooled minimal genome-wide sgRNA libraries to drive oncology drug discovery
Cancer Research·2024
Tracing back primed resistance in cancer via sister cells
Nature Communications·2024· 16 citedOpen Access
Single-cell functional genomics reveals determinants of sensitivity and resistance to natural killer cells in blood cancers
Immunity·2023· 56 citedOpen Access
High-Throughput Screens Identify NEDD8 Inhibition As a Strategy to Augment Natural Killer Cell Cytotoxicity Against Blood Cancers
Blood·2023· 1 citedOpen Access
PB2158: RELAPSING/REFRACTORY ABDOMINAL WALL EXTRA-MEDULLARY PLASMACYTOMAS DEMONSTRATING A RAPID COMPLETE RESPONSE TO BELANTAMAB MAFODOTIN
HemaSphere·2023Open Access
Abstract 667: Single-cell functional genomics of natural killer cell evasion by tumor cells
Cancer Research·2023
Abstract 2912: High-throughput screening and single-cell transcriptomics identify synergies between oncology drugs and natural killer cell immunotherapy
Cancer Research·2023
Single-Cell Functional Genomics of Natural Killer Cell Interaction with Blood Cancers
Blood·2022· 2 cited
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Frequent Co-authors

Olli Dufva(15), Satu Mustjoki(14), Jay Klievink(12), Dean A. Lee(11), Päivi Östling(10), Pekka Ellonen(9), Matti Kankainen(9), Olli Kallioniemi(9), Tiina Hannunen(8), Tero Aittokallio(8), Tuomas Mirtti(8), Antti Rannikko(8), Petra Nygren(8), Jonas Bouhlal(8), Essi Laajala(8), Petri Pölönen(7), Sara Gandolfi(7), Michal Sheffer(7), Constantine S. Mitsiades(7), Olga Dashevsky(6)