Yael Marantz

Teva Pharmaceuticals (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index1.3kcitations25works0.02yr avg
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Research Topics

Receptor Mechanisms and Signaling(10), Photoreceptor and optogenetics research(6), Photosynthetic Processes and Mechanisms(5), Neuroscience and Neuropharmacology Research(4), Computational Drug Discovery Methods(4)

Publications25 total

Site-specific deuterium substitution: A viable approach in drug discovery and development
Drug Metabolism and Pharmacokinetics·2019· 1 cited
A structural approach to reimagining community: biomimicry, biophilia and living labs
Open University of Cape Town (University of Cape Town)·2017Open Access
Laquinimod arrests experimental autoimmune encephalomyelitis by activating the aryl hydrocarbon receptor
Proceedings of the National Academy of Sciences·2016· 133 citedOpen Access
Discovery of a Potent, S1P<sub>3</sub>-Sparing Benzothiazole Agonist of Sphingosine-1-Phosphate Receptor 1 (S1P<sub>1</sub>)
ACS Medicinal Chemistry Letters·2010· 19 citedOpen Access
Benzofuran Derivatives as Potent, Orally Active S1P<sub>1</sub> Receptor Agonists: A Preclinical Lead Molecule for MS
ACS Medicinal Chemistry Letters·2010· 37 citedOpen Access
Small molecule correctors of F508del-CFTR discovered by structure-based virtual screening
Journal of Computer-Aided Molecular Design·2010· 87 citedOpen Access
G Protein Coupled Receptors - In Silico Drug Discovery and Design
Current Topics in Medicinal Chemistry·2010· 27 cited
G Protein-Coupled Receptors: Target-Based In Silico Screening
Current Pharmaceutical Design·2009· 34 cited
SeleX-CS: A New Consensus Scoring Algorithm for Hit Discovery and Lead Optimization
Journal of Chemical Information and Modeling·2009· 34 cited
VRX-03011, a novel 5-HT4 agonist, enhances memory and hippocampal acetylcholine efflux
Neuropharmacology·2007· 93 cited
O3–05–03: PRX–03140: a novel 5–HT4 partial agonist with a dual cholinergic/disease–modifying mechanism for the treatment of Alzheimer disease
Alzheimer s & Dementia·2006· 5 cited
An Integrated in Silico 3D Model-Driven Discovery of a Novel, Potent, and Selective Amidosulfonamide 5-HT<sub>1A</sub> Agonist (PRX-00023) for the Treatment of Anxiety and Depression
Journal of Medicinal Chemistry·2006· 140 citedOpen Access
G protein-coupled receptors: <i>In silico</i> drug discovery in 3D
Proceedings of the National Academy of Sciences·2004· 146 citedOpen Access
PREDICT modeling and in‐silico screening for G‐protein coupled receptors
Proteins Structure Function and Bioinformatics·2004· 104 cited
Modeling the 3D structure of GPCRs: advances and application to drug discovery.
PubMed·2003· 80 cited
Proton-Collecting Properties of Bovine Heart Cytochrome <i>c</i> Oxidase:  Kinetic and Electrostatic Analysis
Biochemistry·2001· 27 cited
ChemInform Abstract: Modeling the 3D Structure of GPCRs from Sequence
ChemInform·2001
Modeling the 3D structure of GPCRs from sequence
Medicinal Research Reviews·2001· 64 citedOpen Access
Dynamics of the Proton Transfer Reaction on the Cytoplasmic Surface of Bacteriorhodopsin
Biochemistry·2001· 63 cited
Biophysical aspects of intra-protein proton transfer
Biochimica et Biophysica Acta (BBA) - Bioenergetics·2000· 34 cited
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Frequent Co-authors

Sharon Shacham(8), Silvia Noiman(8), Oren M. Becker(6), Shay Bar‐Haim(6), Zvi Naor(5), Esther Nachliel(5), Ori Kalid(4), Merav Fichman(4), Hanoch Senderowitz(4), Menachem Gutman(4), Boaz Inbal(3), Alexander Heifetz(3), Anurag Sharadendu(3), Noa Avisar(3), Maya Topf(3), Nili Schutz(3), Mercedes Lobera(3), Dora Toledo Warshaviak(2), Srinivasa R. Cheruku(2), Eric G. Mohler(2)