Graeme J. Sills

University of Glasgow — United Kingdom

Medicine · Health Sciences

47h-index9.6kcitations167works15.72yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Epilepsy research and treatment(116), Pharmacological Effects and Toxicity Studies(67), Neuroscience and Neuropharmacology Research(65), Drug Transport and Resistance Mechanisms(28), Genetics and Neurodevelopmental Disorders(23)

Publications154 total

Predicting Drug Response with Multi-Task Gradient-Boosted Trees in Epilepsy
2025Open Access
Genome-wide association meta-analyses of drug-resistant epilepsy
EBioMedicine·2025· 8 citedOpen Access
Testing for pharmacogenomic predictors of ppRNFL thinning in individuals exposed to vigabatrin
Frontiers in Neuroscience·2023Open Access
Pharmacological diversity amongst approved and emerging antiseizure medications for the treatment of developmental and epileptic encephalopathies
Therapeutic Advances in Neurological Disorders·2023· 24 citedOpen Access
A pharmacogenomic assessment of psychiatric adverse drug reactions to levetiracetam
Epilepsia·2022· 27 citedOpen Access
Lamotrigine versus levetiracetam or zonisamide for focal epilepsy and valproate versus levetiracetam for generalised and unclassified epilepsy: two SANAD II non-inferiority RCTs
Health Technology Assessment·2021· 20 citedOpen Access
High‐mobility group box 1 as a predictive biomarker for drug‐resistant epilepsy: A proof‐of‐concept study
Epilepsia·2021· 37 citedOpen Access
The Impacts of Surgery and Intracerebral Electrodes in C57BL/6J Mouse Kainate Model of Epileptogenesis: Seizure Threshold, Proteomics, and Cytokine Profiles
Frontiers in Neurology·2021· 14 citedOpen Access
Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications
Frontiers in Pharmacology·2021· 19 citedOpen Access
Assessing the role of rare genetic variants in drug‐resistant, non‐lesional focal epilepsy
Annals of Clinical and Translational Neurology·2021· 26 citedOpen Access
The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial
The Lancet·2021· 202 citedOpen Access
The SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide, or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial
The Lancet·2021· 183 citedOpen Access
The ups and downs of alkyl‐carbamates in epilepsy therapy: How does cenobamate differ?
Epilepsia·2021· 64 citedOpen Access
C. elegans as a Potential Model for Acute Seizure-Like Activity
Neuromethods·2021· 2 citedOpen Access
A multiorganism pipeline for antiseizure drug discovery: Identification of chlorothymol as a novel γ‐aminobutyric acidergic anticonvulsant
Epilepsia·2020· 13 citedOpen Access
Study protocol for a pragmatic randomised controlled trial comparing the effectiveness and cost-effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of standard and new antiepileptic drugs (SANAD-II)
BMJ Open·2020· 9 citedOpen Access
Pharmacoresponse in Genetic Generalized Epilepsy: A Genome-Wide Association Study
Pharmacogenomics·2020· 33 citedOpen Access
Testing association of rare genetic variants with resistance to three common antiseizure medications
Epilepsia·2020· 32 citedOpen Access
Functional analysis of epilepsy‐associated variants in STXBP1/Munc18‐1 using humanized <i>Caenorhabditis elegans</i>
Epilepsia·2020· 46 citedOpen Access
Mechanisms of action of currently used antiseizure drugs
Neuropharmacology·2020· 457 citedOpen Access
page 1 of 8Next →

Frequent Co-authors

Martin J. Brodie(26), Anthony G Marson(12), Elaine Butler(9), Nikolas Hitiris(7), John Paul Leach(7), Linda J. Stephen(7), Gerard Forrest(7), Munir Pirmohamed(6), Rajiv Mohanraj(5), Patrick Kwan(5), Stephen Howell(5), Richard Appleton(5), Norman Delanty(4), Gianpiero L. Cavalleri(4), Richard Brown(4), Melissa Maguire(4), Elaine A. Wilson(4), Ana Alfirevic(3), Chantal Depondt(3), Sanjay M. Sisodiya(3)