Hyun Chul Koh

Brigham and Women's Hospital — United States

Agricultural and Biological Sciences · Life Sciences

28h-index3.0kcitations74works0.72yr avg
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Research Topics

Pesticide Exposure and Toxicity(11), Parkinson's Disease Mechanisms and Treatments(9), Autophagy in Disease and Therapy(9), Adenosine and Purinergic Signaling(7), Neuroscience of respiration and sleep(6)

Publications74 total

CK2α Regulates Endoplasmic Reticulum Stress-Mediated Mitophagy via the PERK/ATF4/CHOP Pathway in Rotenone-Treated SH-SY5Y Cells
Molecular Neurobiology·2025· 2 cited
MON-695 Diurnal Rhythm in Meal Responses of Hunger and Appetite in Bariatric Surgery Patients One Year After Vertical Sleeve Gastrectomy
Journal of the Endocrine Society·2025Open Access
OC26 - 24-hour dynamic metabolic phenotyping in individuals after bariatric surgery
European Journal of Endocrinology·2025Open Access
The role of CK2 in the regulation of mitochondrial autophagy induced by rotenone
Toxicology Letters·2023· 6 cited
Chaperon-mediated autophagy can regulate diquat-induced apoptosis by inhibiting α-synuclein accumulation cooperatively with macroautophagy
Food and Chemical Toxicology·2021· 13 cited
FUNDC1 regulates receptor-mediated mitophagy independently of the PINK1/Parkin-dependent pathway in rotenone-treated SH-SY5Y cells
Food and Chemical Toxicology·2020· 25 cited
NF-κB/mTOR-mediated autophagy can regulate diquat-induced apoptosis
Archives of Toxicology·2019· 65 cited
Efficient genome editing by FACS enrichment of paired D10A Cas9 nickases coupled with fluorescent proteins
Archives of Pharmacal Research·2018· 5 cited
NF‐κB/p53‐activated inflammatory response involves in diquat‐induced mitochondrial dysfunction and apoptosis
Environmental Toxicology·2018· 64 cited
PGAM5 regulates PINK1/Parkin-mediated mitophagy via DRP1 in CCCP-induced mitochondrial dysfunction
Toxicology Letters·2017· 183 cited
A Very Rare Case of an Epiglottic Vallecular Cyst Presenting With Active Bleeding Treated via Endoscopic Band Ligation
The American Journal of Gastroenterology·2017
In vivo high-throughput profiling of CRISPR–Cpf1 activity
Nature Methods·2016· 392 citedOpen Access
PPAR-γ activation attenuates deltamethrin-induced apoptosis by regulating cytosolic PINK1 and inhibiting mitochondrial dysfunction
Toxicology Letters·2016· 26 cited
PTEN Promotes Dopaminergic Neuronal Differentiation Through Regulation of ERK-Dependent Inhibition of S6K Signaling in Human Neural Stem Cells
Stem Cells Translational Medicine·2016· 33 citedOpen Access
Progressive loss of nigrostriatal dopaminergic neurons induced by inflammatory responses to fipronil
Toxicology Letters·2016· 18 cited
Clearance of Damaged Mitochondria Through PINK1 Stabilization by JNK and ERK MAPK Signaling in Chlorpyrifos-Treated Neuroblastoma Cells
Molecular Neurobiology·2016· 52 cited
Insulin Signaling Augments eIF4E-Dependent Nonsense-Mediated mRNA Decay in Mammalian Cells
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms·2015· 9 cited
m<scp>TOR</scp> inhibition by rapamycin protects against deltamethrin‐induced apoptosis in <scp>PC</scp>12 Cells
Environmental Toxicology·2015· 39 cited
Dynamin-related protein 1 mediates mitochondria-dependent apoptosis in chlorpyrifos-treated SH-SY5Y cells
NeuroToxicology·2015· 36 citedOpen Access
S6K Promotes Dopaminergic Neuronal Differentiation Through PI3K/Akt/mTOR-Dependent Signaling Pathways in Human Neural Stem Cells
Molecular Neurobiology·2015· 42 cited
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Frequent Co-authors

Jae Hyeon Park(17), In Chul Shin(16), Jeong Eun Lee(14), Yun Sun Park(5), Sang‐Hun Lee(4), Soo‐Jin Lee(4), Chang‐Hwan Park(4), Juyeon Ko(4), Chang Ho Lee(4), Ju Seop Kang(4), Yeo-Woon Ki(3), Ji‐Yeon Lee(3), Mi‐Yoon Chang(3), Yong‐Sung Lee(3), Min Jeong Kang(3), Suk Ju Gil(3), Jin Sun Kang(3), Mi Sun Lim(3), Jungwook Hwang(3), Doo Jin Paik(3)