Sevda Manap

Kafkas University — Turkey

Chemistry · Physical Sciences

12h-index411citations52works4.92yr avg
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Research Topics

Synthesis and biological activity(31), Synthesis and Characterization of Heterocyclic Compounds(30), Click Chemistry and Applications(12), Phenothiazines and Benzothiazines Synthesis and Activities(9), Synthesis and Biological Evaluation(5)

Publications52 total

Synthesis, characterization of novel 2-methoxy-6-((3-substituted-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)iminomethyl)phenyl 4-methylbenzoates and their molecular docking parameters with acetylcholinesterase and butyrylcholinesterase: an in silico mechanism and ADMET investigation
Journal of the Iranian Chemical Society·2026
Novel Mannich Bases Based on Schiff Bases: Synthesis, Biological Activities, Computational Approach, and Anticancer Analysis with Molecular Docking
Acta chimica slovenica·2025Open Access
Structure-guided discovery of submicromolar 1,2,4-triazole–Schiff-base inhibitors of glutathione reductase
International Journal of Biological Macromolecules·2025
Synthesis, spectroscopic characterization, and multiscale computational ınvestigation of a novel 1,2,4-triazole derivative targeting AChE, BChE, and COX enzymes
Structural Chemistry·2025· 1 citedOpen Access
Synthesis and Computational Evaluation of <i>N</i>-Acetyl-Derived Schiff Bases Incorporating 1,2,4-Triazoles for Dual Inhibition of Prostate Cancer Cells and Carbonic Anhydrases
ACS Omega·2025· 4 citedOpen Access
Novel triazole-based N-Acetyl schiff bases: Synthesis, computational analysis, and acetylcholinesterase and butyrylcholinesterase inhibitory potential for Alzheimer's disease
Journal of Molecular Structure·2025· 3 cited
Novel 2-methoxy-4-(((3-methyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)-imino)-methyl)-phenyl benzoate as a potential drug candidate: Synthesis, spectroscopy, TD-DFT, NBO, TDM, FMO, MEP, molecular docking, and molecular dynamics studies
Journal of Molecular Structure·2025· 7 cited
Antibacterial and antioxidant activities of novel 2-ethoxy- 4-[(4,5-dihydro-1H-1,2,4-triazol-5-one-4-yl)azomethine]- phenyl 3-methoxybenzoate derivatives
Journal of Research in Pharmacy·2025Open Access
Synthesis, design, and cholinesterase inhibitory activity of novel 1,2,4-triazole Schiff bases: A combined experimental and computational approach
International Journal of Biological Macromolecules·2025· 23 cited
Synthesis, Antimicrobial and Antioxidant Activities of 3-Alkyl(aryl)-4-(3-methoxy-4-hydroxybenzylideneamino)-4,5-dihydro-1H-1,2,4-triazol-5-one Derivatives
Chemistry Africa·2024· 4 cited
Novel Schiff Bases: Synthesis, Characterization, Bioactivity, Cytotoxicity, and Computational Evaluations
Polycyclic aromatic compounds·2024· 16 cited
Synthesis, characterization of novel mannich bases and their acetylcholinesterase and glutathione S-transferase inhibitory properties: An in vitro and in silico mechanism research
Journal of Molecular Structure·2024· 10 cited
Synthesis and Biological Evaluation of 3-Alkyl(Aryl)-4-(4-methylthio-benzylideneamino)-4,5-dihidro-1H-1,2,4-triazol-5-one Derivatives
Caucasian Journal of Science·2024Open Access
Synthesis, Antimicrobial and Antioxidant Activities of 3-Alkyl(aryl)-4-(3-methoxy-4-hydroxybenzylideneamino)-4,5-dihydro-1H-1,2,4-triazol-5-one Derivatives
Research Square (Research Square)·2024Open Access
Synthesis, Biological and Acidic Properties of Novel 2-Methoxy-6-[(3-Alkyl/Aryl-4,5-Dihydro-1H- 1,2,4-Triazol-5-one-4-yl)-Azomethin]-Phenyl p-Nitrobenzoate Derivatives
Chemistry & Chemical Technology·2023· 1 citedOpen Access
Synthesis, molecular modeling investigation, molecular dynamic and ADME prediction of some novel Mannich bases derived from 1,2,4-triazole, and assessment of their anticancer activity
Journal of Biomolecular Structure and Dynamics·2023· 35 cited
Determination of HNP and pKa Values of Some 3-Alkyl(Aryl)-4-phthalimido-4,5-dihydro-1H-1,2,4-triazol-5-one Compounds by Semi-Neutralization Method
Caucasian Journal of Science·2022Open Access
Bazı Yeni Potansiyel Biyolojik Aktif 2-Etoksi-6-(3-substitue-4,5-dihidro-1H-1,2,4-triazol-5-on-4-il-azometin)-fenil Fenilasetat Türevlerinin Sentezi, Karakterizasyonu ve Antioksidan Özellikleri
European Journal of Science and Technology·2022Open Access
Synthesis, Biological and Acidic Properties of Some New 2-Ethoxy-4-[(3-alkyl-4,5-dihydro-1H-1,2,4-triazol-5-one-4-yl)-azomethine]-phenyl 2-Methylbenzoate Derivatives
Moscow University Chemistry Bulletin·2022
Synthesis and Antioxidant and Antibacterial Activities of Novel 4-({[3-Alkyl(aryl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-4-yl]imino}methyl)phenyl 4-Nitrobenzoate Derivatives
Russian Journal of Organic Chemistry·2022· 3 cited
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Frequent Co-authors

Haydar Yüksek(42), Murat Beytur(23), Özlem Gürsoy Kol(15), Hilal Medetalibeyoğlu(14), Onur Akyıldırım(10), Muzaffer Alkan(8), Gül Kotan(7), Ahmet Buğra Ortaakarsu(7), Abdurrahman Atalay(7), Gül Özdemir(6), Burak Tüzün(5), Faruk Kardaş(4), Mehmet Lütfi Yola(4), Fevzi Aytemiz(4), Necip Atar(3), Ömer Faruk Karataş(3), Fikret Türkan(3), Abdülmelik Aras(3), Ahmet Harmankaya(3), Kenan Gören(3)