Clare C. Davies

Cancer Research UK Clinical Trials Unit — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

29h-index3.1kcitations53works4.32yr avg
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Research Topics

Epigenetics and DNA Methylation(11), Cancer-related gene regulation(11), NF-κB Signaling Pathways(8), Horticultural and Viticultural Research(6), Heart Rate Variability and Autonomic Control(5)

Publications52 total

Arginine methylation regulates Ewing sarcoma cell viability in a EWSR1::FLI1 dependent manner and provides a therapeutic opportunity
Frontiers in Oncology·2025Open Access
MYBL2 maintains stemness and promotes theta-mediated end joining in triple negative breast cancer
2025Open Access
PRMT5-regulated splicing of DNA repair genes drives chemoresistance in breast cancer stem cells
Oncogene·2024· 13 citedOpen Access
DNA Repair and Therapeutic Strategies in Cancer Stem Cells
Cancers·2023· 74 citedOpen Access
Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair
Nature Communications·2021· 42 citedOpen Access
Implementation of CRISPR/Cas9 Genome Editing to Generate Murine Lung Cancer Models That Depict the Mutational Landscape of Human Disease
Frontiers in Cell and Developmental Biology·2021· 32 citedOpen Access
Structural and biochemical evaluation of bisubstrate inhibitors of protein arginine N-methyltransferases PRMT1 and CARM1 (PRMT4)
Biochemical Journal·2020· 17 citedOpen Access
Crystal structure of CARM1 in complex with inhibitor UM079
2019· 5 citedOpen Access
PRMTs and Arginine Methylation: Cancer’s Best-Kept Secret?
Trends in Molecular Medicine·2019· 346 cited
Post‐veraison restriction of phloem import into Riesling (<scp><i>Vitis vinifera</i></scp>L.) berries induces transient and stable changes to fermentation‐derived and varietal wine volatiles
Australian Journal of Grape and Wine Research·2019· 9 cited
PO-010 PRMT1 methylates and regulates the deubiquitinating enzyme USP11 modulating the DNA damage response in breast cancer cells
ESMO Open·2018· 1 citedOpen Access
Linking PRMT5 to breast cancer stem cells: New therapeutic opportunities?
Molecular & Cellular Oncology·2018· 11 citedOpen Access
PRMT5 Is a Critical Regulator of Breast Cancer Stem Cell Function via Histone Methylation and FOXP1 Expression
Cell Reports·2017· 199 citedOpen Access
Peduncle-girdling of Shiraz (<i>Vitis vinifera</i>L.) bunches and sugar concentration at the time of girdling affect wine volatile compounds
Australian Journal of Grape and Wine Research·2017· 18 cited
PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination
Molecular Cell·2017· 169 citedOpen Access
Citrullination of histone H3 drives IL-6 production by bone marrow mesenchymal stem cells in MGUS and multiple myeloma
Leukemia·2016· 53 citedOpen Access
Identifying novel protein interactions: Proteomic methods, optimisation approaches and data analysis pipelines
Methods·2015· 33 citedOpen Access
Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma
Pancreatology·2015· 1 cited
ERK5 Is a Critical Mediator of Inflammation-Driven Cancer
Cancer Research·2015· 58 citedOpen Access
Impaired JNK Signaling Cooperates with <i>KrasG12D</i> Expression to Accelerate Pancreatic Ductal Adenocarcinoma
Cancer Research·2014· 32 citedOpen Access
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Frequent Co-authors

Aristides G. Eliopoulos(9), Lawrence S. Young(8), Simon Heller(8), N. Harris(6), Rob H. Ireland(6), Paul K. Boss(5), Kelly Chiang(5), María Pilar Sánchez-Bailón(4), Mark Skehel(4), Cathy Tournier(4), Celia Emery(4), Ciara Ward(4), Emma A. Gunnell(4), Christine Böttcher(3), Thomas L. Clarke(3), Henry O. Nyongesa(3), Reza Saatchi(3), Katherine G. Finegan(3), Gavin S. McNee(3), Axel Behrens(3)