Brian Cleaver

University of Florida — United States

Agricultural and Biological Sciences · Life Sciences

14h-index957citations27works105.02yr avg
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Research Topics

Reproductive Physiology in Livestock(8), CAR-T cell therapy research(7), Virus-based gene therapy research(6), Veterinary Equine Medical Research(6), Lysosomal Storage Disorders Research(5)

Publications27 total

RNA aggregates harness the danger response for potent cancer immunotherapy
Cell·2024· 105 citedOpen Access
Adeno-associated virus-mediated gene therapy in a patient with Canavan disease using dual routes of administration and immune modulation
Molecular Therapy — Methods & Clinical Development·2023· 26 citedOpen Access
mRNA aggregates harness danger response for potent cancer immunotherapy
2023· 7 citedOpen Access
ATIM-34. SINGLE-CELL RNA SEQUENCING REVEALS DYNAMIC IMMUNE RESPONSE CHANGES IN GLIOBLASTOMA PATIENT WITH DURABLE COMPLETE RESPONSE TO CMV PP65-LAMP RNA-PULSED DENDRITIC VACCINES
Neuro-Oncology·2019· 1 citedOpen Access
Pompe disease gene therapy: neural manifestations require consideration of CNS directed therapy
Annals of Translational Medicine·2019· 53 citedOpen Access
PDCT-08. TRACKING THE T CELL REPERTOIRE AFTER ADOPTIVE CELL THERAPY IN PEDIATRIC PATIENTS WITH RECURRENT MEDULLOBLASTOMA
Neuro-Oncology·2018Open Access
Enabling redosing of AAV by immune management in Pompe disease: Preclinical to clinical studies
Molecular Genetics and Metabolism·2018· 2 cited
PDCT-15. Re-MATCH: A PHASE 2 MULTI-INSTITUTIONAL CLINICAL TRIAL OF ADOPTIVE CELLULAR THERAPY FOLLOWING MYELOABLATIVE OR NON-MYELOABLATIVE CHEMOTHERAPY IN CHILDREN AND YOUNG ADULTS WITH RECURRENT MEDULLOBLASTOMA AND PNETs
Neuro-Oncology·2016Open Access
472. Evaluation of Re-Administration of a Recombinant Adeno-Associated Vector Expressing Acid-Alpha-Glucosidase (rAAV9-DES-hGAA) in Pompe Disease: Preclinical to Clinical Planning
Molecular Therapy·2016Open Access
A scalable method for the production of high-titer and high-quality adeno-associated type 9 vectors using the HSV platform
Molecular Therapy — Methods & Clinical Development·2016· 48 citedOpen Access
Evaluation of Readministration of a Recombinant Adeno-Associated Virus Vector Expressing Acid Alpha-Glucosidase in Pompe Disease: Preclinical to Clinical Planning
Human Gene Therapy Clinical Development·2015· 91 citedOpen Access
IT-35 * cGMP MANUFACTURING OF EX VIVO EXPANDED TUMOR-SPECIFIC T CELLS AND AMPLIFIED TUMOR RNA-PULSED DC VACCINES TARGETING GLIOBLASTOMA AND MEDULLOBLASTOMA
Neuro-Oncology·2014Open Access
Phase I/II Trial of Diaphragm Delivery of Recombinant Adeno-Associated Virus Acid Alpha-Glucosidase (rAAV1-CMV- <i>GAA</i> ) Gene Vector in Patients with Pompe Disease
Human Gene Therapy Clinical Development·2014· 45 cited
A simplified purification protocol for recombinant adeno-associated virus vectors
Molecular Therapy — Methods & Clinical Development·2014· 74 citedOpen Access
Phase I/II Trial of Adeno-Associated Virus–Mediated Alpha-Glucosidase Gene Therapy to the Diaphragm for Chronic Respiratory Failure in Pompe Disease: Initial Safety and Ventilatory Outcomes
Human Gene Therapy·2013· 154 citedOpen Access
Preclinical Potency and Safety Studies of an AAV2-Mediated Gene Therapy Vector for the Treatment of <i>MERTK</i> Associated Retinitis Pigmentosa
Human Gene Therapy Clinical Development·2013· 94 citedOpen Access
Pompe disease gene therapy
Human Molecular Genetics·2011· 92 cited
Clinical Aspects of Seasonality in Mares
Elsevier eBooks·2007· 5 cited
Contributors
Elsevier eBooks·2007
Effects of ovarian input on GnRH and LH secretion immediately postovulation in pony mares
Theriogenology·2001· 7 cited
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Frequent Co-authors

Nathalie Clément(14), Barry J. Byrne(10), Thomas J. Conlon(6), Duane A. Mitchell(6), Manuela Corti(6), Barbara K. Smith(4), Marcia Hodik(4), Roland W. Herzog(4), Dan C. Sharp(4), Anjelika Dechkovskaia(4), Shelley Collins(3), Cathryn Mah(3), Lee Ann Lawson(3), David D. Fuller(3), Saleem Islam(3), Paul Castillo(3), Kirsten E. Coleman(3), Maryam Rahman(3), Ashley Ghiaseddin(3), Elias Sayour(3)