Douglas R. Martin

Auburn University — United States

Medicine · Health Sciences

32h-index3.0kcitations106works1.02yr avg
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Research Topics

Lysosomal Storage Disorders Research(46), Virus-based gene therapy research(31), Glycosylation and Glycoproteins Research(16), Cellular transport and secretion(14), RNA Interference and Gene Delivery(7)

Publications106 total

AAV9 Gene Therapy in Type II GM1 Gangliosidosis — A Phase 1–2 Trial
New England Journal of Medicine·2026
Five-year analysis of efficacy and safety of a bidirectional AAV gene therapy in Tay-Sachs sheep
Journal of Clinical Investigation·2025Open Access
Inter-evaluator bias and applicability of feline body condition score from visual assessment
Frontiers in Veterinary Science·2025Open Access
Single Cell Multiomics Across Nine Mammals Reveals Cell Type Specific Regulatory Conservation in the Brain
2025Open Access
AAV9 Gene Therapy in GM1 Gangliosidosis Type II: A Phase 1/2 Trial
2025· 2 citedOpen Access
Secondary accumulation of lyso-platelet activating factors in lysosomal storage diseases
Molecular Genetics and Metabolism·2025Open Access
Secondary accumulation of lyso-platelet activating factors in lysosomal diseases
Molecular Genetics and Metabolism·2025
Clinical and biochemical abnormalities in a feline model of GM2 activator deficiency
Molecular Genetics and Metabolism·2024· 1 citedOpen Access
Intravenous gene therapy improves lifespan and clinical outcomes in feline Sandhoff Disease
2024· 1 citedOpen Access
Sperm collection in the domestic cat: A comparison of two techniques
Theriogenology·2024· 2 cited
Evaluation of fecal sample collection methods for feline gut microbiome profiling: fecal loop vs. litter box
Frontiers in Microbiology·2024· 2 citedOpen Access
The Characteristics and Function of Small Extracellular Vesicles Derived from Human Bone Marrow and Umbilical Cord Mesenchymal Stromal Cells Are Influenced by Cell Culture Conditions
Stem Cells and Development·2024· 4 cited
Life‐Limiting Peripheral Organ Dysfunction in Feline Sandhoff Disease Emerges after Effective <scp>CNS</scp> Gene Therapy
Annals of Neurology·2023· 6 citedOpen Access
A pentasaccharide for monitoring pharmacodynamic response to gene therapy in GM1 gangliosidosis
EBioMedicine·2023· 17 citedOpen Access
Rabies: who should care?
Journal of the American Veterinary Medical Association·2022· 9 cited
Improving animal health through research at Auburn University
American Journal of Veterinary Research·2022Open Access
AAVrh10 vector corrects pathology in animal models of GM1 gangliosidosis and achieves widespread distribution in the CNS of nonhuman primates
Molecular Therapy — Methods & Clinical Development·2022· 17 citedOpen Access
Whole-Genome Shotgun Metagenomic Sequencing Reveals Distinct Gut Microbiome Signatures of Obese Cats
Microbiology Spectrum·2022· 46 citedOpen Access
AAV gene therapy for Tay-Sachs disease
Nature Medicine·2022· 123 citedOpen Access
Real-time MR tracking of AAV gene therapy with βgal-responsive MR probe in a murine model of GM1-gangliosidosis
Molecular Therapy — Methods & Clinical Development·2021· 16 citedOpen Access
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Frequent Co-authors

Heather Gray‐Edwards(22), Miguel Sena‐Esteves(22), Nancy R. Cox(18), Henry J. Baker(15), Ashley N. Randle(14), Aime K. Johnson(13), Allison M. Bradbury(13), Victoria J. McCurdy(11), Brandon L. Brunson(10), Misako Hwang(9), Nancy E. Morrison(7), Amanda L. Gross(7), Ana Rita Batista(6), Nouha Salibi(6), Ronald J. Beyers(6), Thomas S. Denney(6), Anne S. Maguire(6), Thomas N. Seyfried(6), Stacy A. Maitland(5), Judith A. Hudson(5)