Fumika Koyano

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index3.4kcitations26works6.02yr avg
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Research Topics

Mitochondrial Function and Pathology(16), Autophagy in Disease and Therapy(14), Parkinson's Disease Mechanisms and Treatments(12), Ubiquitin and proteasome pathways(9), Alzheimer's disease research and treatments(2)

Publications26 total

The reaction mechanism for glycolysis side product degradation by Parkinson’s disease–linked DJ-1
The Journal of Cell Biology·2025· 3 citedOpen Access
Quality control of ABCD3 by the VCP-FAF2 complex suppresses excessive pexophagy
Autophagy·2025· 1 citedOpen Access
AAA+ ATPase chaperone p97/VCPFAF2 governs basal pexophagy
Nature Communications·2024· 14 citedOpen Access
Critical role of mitochondrial ubiquitination and the OPTN–ATG9A axis in mitophagy
The Journal of Cell Biology·2020· 194 citedOpen Access
Parkin‐mediated ubiquitylation redistributes MITOL/March5 from mitochondria to peroxisomes
EMBO Reports·2019· 54 citedOpen Access
Parkin mediates selective elimination of damaged mitochondria and redistributes MITOL/March5 from mitochondria to peroxisomes
The Japanese Biochemical Society·2019
Parkin recruitment to impaired mitochondria for nonselective ubiquitylation is facilitated by MITOL
Journal of Biological Chemistry·2019· 112 citedOpen Access
Establishment and characterization of a Parkinsonʼs disease model mice
The Japanese Biochemical Society/The Molecular Biology Society of Japan·2017
Characterization of Parkin substrate specificity in Mitochondrial quality control
The Japanese Biochemical Society/The Molecular Biology Society of Japan·2017
Parkinson’s disease-related DJ-1 functions in thiol quality control against aldehyde attack in vitro
Scientific Reports·2017· 53 citedOpen Access
Phosphorylated ubiquitin acts as a lighthouse for mitochondrial quality assurance
The Molecular Biology Society of Japan·2016
Unexpected mitochondrial matrix localization of Parkinson's disease‐related <scp>DJ</scp>‐1 mutants but not wild‐type <scp>DJ</scp>‐1
Genes to Cells·2016· 23 citedOpen Access
PINK1 phosphorylated Ser65 ubiquitin regulates Parkin E3 activity
The Japanese Biochemical Society/The Molecular Biology Society of Japan·2015
Site-specific interaction mapping of phosphorylated Parkin and phosphorylated ubiquitin to uncover Parkin activation
The Japanese Biochemical Society/The Molecular Biology Society of Japan·2015
Site-specific Interaction Mapping of Phosphorylated Ubiquitin to Uncover Parkin Activation
Journal of Biological Chemistry·2015· 56 citedOpen Access
Phosphorylated ubiquitin chain is the genuine Parkin receptor
The Journal of Cell Biology·2015· 256 citedOpen Access
Phosphorylated ubiquitin chain is the genuine Parkin receptor
The Journal of Experimental Medicine·2015· 4 cited
Molecular mechanisms underlying PINK1 and Parkin catalyzed ubiquitylation of substrates on damaged mitochondria
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research·2015· 43 cited
Phos-Tag PAGE: uncovering the role of phosphorylation resisting Parkinson’s disease
Electrophoresis Letters·2015Open Access
[How E3 activity of Parkin is enhanced by damaged mitochondria].
PubMed·2014
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Frequent Co-authors

Noriyuki Matsuda(25), Keiji Tanaka(17), Mayumi Kimura(13), Kei Okatsu(11), Hidetaka Kosako(11), Koji Yamano(10), Yasushi Saeki(7), Etsu Go(4), Bruno B. Queliconi(4), Keiji Tanaka(4), Takatsugu Hirokawa(3), Waka Kojima(3), Yoko Kimura(2), Hikaru Tsuchiya(2), Hidehito Yoshihara(2), Toshihiko Oka(2), Masahiro Iguchi(2), Yuki Kujuro(2), Yukio Fujiki(2), Masaki Mishima(2)