Rachael N. McVicar

Sanford Burnham Prebys Medical Discovery Institute — United States

Medicine · Health Sciences

9h-index1.5kcitations29works1.32yr avg
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Research Topics

Neonatal Respiratory Health Research(10), SARS-CoV-2 and COVID-19 Research(8), COVID-19 Clinical Research Studies(5), Respiratory Support and Mechanisms(5), Cancer Cells and Metastasis(4)

Publications28 total

Genome-Wide Interrogation of SARS-CoV-2 RNA-Protein Interactions Uncovers Hidden Regulatory Sites
2025Open Access
Modeling patient-specific adenocarcinoma as spheroids enhances the authenticity of cancer hallmarks and therapeutic susceptibility
Heliyon·2025Open Access
Modeling the Aging Human Lung: Generation of a Senescent Human Lung Organoid Culture System
2025· 1 citedOpen Access
iPSC-Derived Epithelial, Mesenchymal, Endothelial, and Immune Cell Co-Culture to Model Airway Barrier Integrity in Lung Health and Disease
Journal of Visualized Experiments·2024
A therapy for suppressing canonical and noncanonical SARS-CoV-2 viral entry and an intrinsic intrapulmonary inflammatory response
Proceedings of the National Academy of Sciences·2024· 9 citedOpen Access
Surfactant Protein B Reduces Respiratory Viral Infectivity in Human Lungs
2024
Investigating Airway Surfactant BPIFA1 in the Developing Human Lung
2024
The Effects of Cell-cell Orientation in Modeling the Hallmarks of Lung Cancer In Vitro
2024
The effects of cell-cell orientation in modeling the hallmarks of lung cancer in vitro
2023· 1 citedOpen Access
1-O-Octadecyl-2-O-benzyl-sn-glyceryl-3-phospho-GS-441524 (V2043). Evaluation of Oral V2043 in a Mouse Model of SARS-CoV-2 Infection and Synthesis and Antiviral Evaluation of Additional Phospholipid Esters with Enhanced Anti-SARS-CoV-2 Activity
Figshare·2023Open Access
Variant <i>STAT4</i> and Response to Ruxolitinib in an Autoinflammatory Syndrome
New England Journal of Medicine·2023· 62 citedOpen Access
Surfactant deficiency increases SARS-CoV-2 canonical and non-canonical viral entry to lung epithelial cells and exacerbates intrapulmonary inflammatory responses
Research Square (Research Square)·2023Open Access
1-<i>O</i>-Octadecyl-2-<i>O</i>-benzyl-<i>sn</i>-glyceryl-3-<i>phospho</i>-GS-441524 (V2043). Evaluation of Oral V2043 in a Mouse Model of SARS-CoV-2 Infection and Synthesis and Antiviral Evaluation of Additional Phospholipid Esters with Enhanced Anti-SARS-CoV-2 Activity
Journal of Medicinal Chemistry·2023· 9 citedOpen Access
The lung employs an intrinsic surfactant-mediated inflammatory response for viral defense
2023Open Access
Discovery and functional interrogation of SARS-CoV-2 protein-RNA interactions
2022· 2 citedOpen Access
Discovery and functional interrogation of SARS-CoV-2 protein-RNA interactions
2022· 4 citedOpen Access
Disease-associated mutations in topoisomerase IIβ result in defective NK cells
Journal of Allergy and Clinical Immunology·2022· 13 citedOpen Access
Using human induced pluripotent stem cells to advance personalized/precision medicine
Elsevier eBooks·2022
Contributors
Elsevier eBooks·2022
Rethinking Remdesivir: Synthesis, Antiviral Activity, and Pharmacokinetics of Oral Lipid Prodrugs
Antimicrobial Agents and Chemotherapy·2021· 68 citedOpen Access
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Frequent Co-authors

Sandra L. Leibel(24), Aaron F. Carlin(13), Evan Y. Snyder(12), Elizabeth M. Kwong(10), Alex E. Clark(10), Ben A. Croker(7), Aaron F. Garretson(6), Rabi Murad(6), Bethany A. Grimmig(6), Emily Smith(6), Anne Bush(5), Robert T. Schooley(4), James R. Beadle(4), Nadejda Valiaeva(4), Xingquan Zhang(4), Rachel E. McMillan(4), Joyce Murphy(4), Karl Y. Hostetler(4), Cameron J. Nowell(4), Eric R. Griffis(4)