Susanne Rolle

Max Delbrück Center — Germany

Medicine · Health Sciences

13h-index767citations18works0.02yr avg
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Research Topics

Vasculitis and related conditions(9), Cell Adhesion Molecules Research(8), Neutrophil, Myeloperoxidase and Oxidative Mechanisms(8), Immune Response and Inflammation(4), Lipoproteins and Cardiovascular Health(2)

Publications18 total

Competitively disrupting the neutrophil-specific receptor–autoantigen CD177:proteinase 3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation
Journal of Biological Chemistry·2022· 13 citedOpen Access
Disrupting the CD177:proteinase 3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation
2021Open Access
β2 Integrin-mediated Cell-Cell Contact Transfers Active Myeloperoxidase from Neutrophils to Endothelial Cells
Journal of Biological Chemistry·2013· 58 citedOpen Access
Complement Receptor Mac-1 Is an Adaptor for NB1 (CD177)-mediated PR3-ANCA Neutrophil Activation
Journal of Biological Chemistry·2010· 109 citedOpen Access
The use of small molecule high-throughput screening to identify inhibitors of the proteinase 3-NB1 interaction
Clinical & Experimental Immunology·2010· 11 citedOpen Access
Aldosterone Abrogates Nuclear Factor κB–Mediated Tumor Necrosis Factor α Production in Human Neutrophils via the Mineralocorticoid Receptor
Hypertension·2010· 33 citedOpen Access
Phosphoinositol 3-kinase-γ mediates antineutrophil cytoplasmic autoantibody-induced glomerulonephritis
Kidney International·2009· 63 citedOpen Access
BK channels in innate immune functions of neutrophils and macrophages
Blood·2008· 35 citedOpen Access
Short-Term Heat Exposure Inhibits Inflammation by Abrogating Recruitment of and Nuclear Factor-κB Activation in Neutrophils Exposed to Chemotactic Cytokines
American Journal Of Pathology·2008· 20 citedOpen Access
Febrile temperatures control antineutrophil cytoplasmic autoantibody–induced neutrophil activation via inhibition of phosphatidylinositol 3‐kinase/Akt
Arthritis & Rheumatism·2007· 6 cited
β2-Integrins and Acquired Glycoprotein IIb/IIIa (GPIIb/IIIa) Receptors Cooperate in NF-κB Activation of Human Neutrophils
Journal of Biological Chemistry·2007· 71 citedOpen Access
Fever-Like Temperatures Affect Neutrophil NF-κB Signaling, Apoptosis, and ANCA-Antigen Expression
Journal of the American Society of Nephrology·2006· 17 cited
The effect of fever‐like temperatures on neutrophil signaling
The FASEB Journal·2005· 20 cited
Integrins and Cytokines Activate Nuclear Transcription Factor-κB in Human Neutrophils
Journal of Biological Chemistry·2004· 76 citedOpen Access
Inhibition of NF-κB by a TAT-NEMO–binding domain peptide accelerates constitutive apoptosis and abrogates LPS-delayed neutrophil apoptosis
Blood·2003· 106 citedOpen Access
Extracellular signal-regulated kinase inhibition by statins inhibits neutrophil activation by ANCA
Kidney International·2003· 61 citedOpen Access
Phosphatidylinositol 3-Kinase Controls Antineutrophil Cytoplasmic Antibodies—Induced Respiratory Burst in Human Neutrophils
Journal of the American Society of Nephrology·2002· 68 cited
HMG-CoA Reductase Inhibitors Decrease Anca-Mediated Activation Of Human Neutrophils
Cleveland Clinic Journal of Medicine·2002

Frequent Co-authors

Ralph Kettritz(18), Friedrich C. Luft(16), Mira Choi(10), Maren Wellner(7), Uwe Jerke(4), Birgit Salanova(4), Claus Scheidereit(2), Madhavi J. Rane(2), Wolfgang Schneider(2), Hermann Haller(2), William M. Nauseef(2), Claudia Eulenberg(2), Stephen F. Marino(2), Oliver Daumke(2), Gunnar Dittmar(1), Behnaz Bayat(1), Sentot Santoso(1), Anje Sporbert(1), M. Cristina Cardoso(1), Waseem Butt(1)