Muthiah Bose

Copenhagen University Hospital — Denmark

Biochemistry, Genetics and Molecular Biology · Life Sciences

5h-index185citations13works0.22yr avg
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Research Topics

BRCA gene mutations in cancer(6), DNA Repair Mechanisms(5), Cancer-related Molecular Pathways(2), Cancer Genomics and Diagnostics(2), Molecular Biology Techniques and Applications(2)

Publications13 total

Functional assessment of protein variants in structured domains by fluorescence cross-correlation spectroscopy
Scientific Reports·2026Open Access
The class II myosin MYH4 safeguards genome integrity and suppresses tumor progression
Journal of Clinical Investigation·2025Open Access
G6PC3 promotes genome maintenance and is a candidate mammary tumor suppressor
JCI Insight·2025Open Access
Precision screening facilitates clinical classification of BRCA2-PALB2 binding variants with benign and pathogenic functional effects
Journal of Clinical Investigation·2025· 1 citedOpen Access
Functional Assessment of Protein Variants in Structured Domains by Fluorescence Cross-Correlation Spectroscopy
2024Open Access
A catalog of curated breast cancer genes
Breast Cancer Research and Treatment·2021· 12 citedOpen Access
Abstract 2335: Heterozygous <i>PALB2</i> mutations cause replication stress and DNA repair defects in carrier derived lymphoblastoid cell lines
Cancer Research·2020
Germline RBBP8 variants associated with early-onset breast cancer compromise replication fork stability
Journal of Clinical Investigation·2020· 32 citedOpen Access
BRCA1 mislocalization leads to aberrant DNA damage response in heterozygous ABRAXAS1 mutation carrier cells
Human Molecular Genetics·2019· 8 citedOpen Access
Abstract 339: Heterozygous germline mutation in <i>ABRAXAS</i> causes BRCA1 mislocalization and DNA damage response defects
Cancer Research·2018
Molecular and functional characterization of ABRAXAS and PALB2 genes in hereditary breast cancer predisposition
2018
Heterozygous mutations in PALB2 cause DNA replication and damage response defects
Nature Communications·2013· 75 citedOpen Access
In Vitro Studies on Erythrosine-Based Photodynamic Therapy of Malignant and Pre-Malignant Oral Epithelial Cells
PLoS ONE·2012· 57 citedOpen Access

Frequent Co-authors

Finn Cilius Nielsen(6), Maria Rossing(5), Katri Pylkäs(4), Kerstin Borgmann(4), Helmut Pospiech(4), Robert Winqvist(4), Claus Storgaard Sørensen(4), Ann Christin Parplys(3), Katrin Rapakko(3), Pentti Nieminen(3), Jan Benada(3), Jayashree Thatte(3), Niina Laurila(3), Felix Meyer(3), Bing Xia(2), Bent Ejlertsen(2), Juliane Sachsenweger(2), Jonas Willmann(2), Marco Groth(2), Lisa Heiserich(2)