Anne Akin

Pfizer (United States) — United States

Chemistry · Physical Sciences

9h-index227citations29works0.02yr avg
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Research Topics

Crystallography and molecular interactions(10), Analytical Chemistry and Chromatography(8), Crystallization and Solubility Studies(5), Click Chemistry and Applications(4), Carbohydrate Chemistry and Synthesis(3)

Publications29 total

Cross-Pharma Collaboration on the Development and Evaluation of a New Mid-Scale Preparative Supercritical Fluid Chromatography Instrument
Organic Process Research & Development·2020· 10 cited
CCDC 1940697: Experimental Crystal Structure Determination
The Cambridge Structural Database·2019Open Access
Overcoming the Challenges of Making a Single Enantiomer N-1 Substituted Tetrazole Prodrug Using a Tin-Mediated Alkylation and Enzymatic Resolution
Organic Process Research & Development·2019· 14 cited
CCDC 1571688: Experimental Crystal Structure Determination
The Cambridge Structural Database·2018Open Access
A Scalable Route for the Regio- and Enantioselective Preparation of a Tetrazole Prodrug: Application to the Multi-Gram-Scale Synthesis of a PCSK9 Inhibitor
Organic Process Research & Development·2017· 24 cited
Feasibility of correlating separation of ternary mixtures of neutral analytes via thin layer chromatography with supercritical fluid chromatography in support of green flash separations
Journal of Chromatography A·2015· 4 cited
Syntheses of Dap-3 Polymyxin Analogues via a Tris-Boc-Protected Polymyxin B Heptapeptide
Synthesis·2015· 9 cited
The Synthesis of a Dopamine D<sub>2</sub> Partial Agonist for the Treatment of Schizophrenia
Organic Process Research & Development·2009· 14 cited
ChemInform Abstract: Practical Synthesis of 1‐(7‐Fluoro‐naphthalen‐1‐yl)‐piperazine Hydrochloride.
ChemInform·2009
The efficient synthesis of (3R,4R,5R)-3-amino-4,5-dimethyl-octanoic acid, a chiral β-amino acid with potent affinity for the α2δ protein
Tetrahedron Letters·2009· 11 cited
Practical Synthesis of 1-(7-Fluoro-naphthalen-1-yl)piperazine Hydrochloride
Synthetic Communications·2008· 7 cited
An Orthogonal Approach to Chiral Method Development Screening
Current Pharmaceutical Analysis·2007· 25 cited
Preparation of CI‐1027 Glucuronide: Metabolite of a Remarkable Lipid‐Modulating Agent
Synthetic Communications·2005· 6 cited
ChemInform Abstract: Synthesis and Microbiological Activity of 5(or 6)‐Methyl‐2‐substituted Benzoxazole and Benzimidazole Derivatives.
ChemInform·1998· 5 cited
Synthesis and microbiological activity of 5(or 6)-methyl-2-substituted benzoxazole and benzimidazole derivatives.
PubMed·1997· 27 cited
Hydrogen bonding Part 54. NMR study of the effects of anesthetics on hydration of choline, acetylcholine and tetraethylammonium halides in aqueous solution
Journal of Molecular Structure·1994· 4 cited
Hydrogen bonding Part 55. IR and thermodynamic study of the lower hydrates of phenylphosphorylcholine and methylphosphorylcholine
Journal of Molecular Structure·1994· 1 cited
ChemInform Abstract: Hydrogen Bonding. Part 45. Thermodynamic and IR Study of the Hydrates of N‐Methylmorpholine Oxide and Quinuclidine Oxide. Effect of Hydrate Stoichiometry on Strength of H‐O‐H×××O‐N Hydrogen Bonds; Implications for the Dissolution of Cellulose in Amine Oxide Solvents.
ChemInform·1992
ChemInform Abstract: Hydrogen Bonding. Part 43. IR and Thermodynamic Study of the Stoichiometry and Stability of Hydrates of Triethylenediamine Oxide.
ChemInform·1992
ChemInform Abstract: Hydrogen Bonding. Part 41. Stoichiometry, Thermodynamics of Dissociation, and IR Spectra of the Hydrates of N,N‐Dimethylpiperazine Dioxide.
ChemInform·1992
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Frequent Co-authors

Kenneth M. Harmon(14), Javier Magano(5), Thomas A. Brandt(4), David W. Piotrowski(4), Liuqing Wei(4), Patricia K. Keefer(4), Michael H. Chen(3), Lydia S. Nowos(2), Mary Beth Tierney(2), I. Yalçin(2), Esin Aki(2), Mark T. Barrila(2), Anne‐Marie Dechert‐Schmitt(2), Pascal Dubé(2), David D. Ford(2), Adam S. Kamlet(2), Chris Limberakis(2), Andrew Pearsall(2), B. Quinn(2), Sarah Rothstein(2)