Lauren L. Orefice

Harvard University — United States

Neuroscience · Life Sciences

15h-index2.2kcitations22works28.02yr avg
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Research Topics

Autism Spectrum Disorder Research(7), Genetics and Neurodevelopmental Disorders(7), Neuroscience and Neuropharmacology Research(5), Nerve injury and regeneration(5), Neurogenesis and neuroplasticity mechanisms(4)

Publications22 total

The developmental timing of spinal touch processing alterations predicts behavioral changes in genetic mouse models of autism spectrum disorders
Nature Neuroscience·2024· 28 citedOpen Access
The developmental timing of spinal touch processing alterations and its relation to ASD-associated behaviors in mouse models
2023· 4 citedOpen Access
Emerging Therapeutic Strategies for Fragile X Syndrome: Q&A
ACS Chemical Neuroscience·2022· 3 citedOpen Access
DeepEthogram, a machine learning pipeline for supervised behavior classification from raw pixels
eLife·2021· 202 citedOpen Access
Author response: DeepEthogram, a machine learning pipeline for supervised behavior classification from raw pixels
2021· 4 citedOpen Access
DeepEthogram: a machine learning pipeline for supervised behavior classification from raw pixels
2020· 30 citedOpen Access
Meissner corpuscles and their spatially intermingled afferents underlie gentle touch perception
Science·2020· 151 citedOpen Access
Peripheral Somatosensory Neuron Dysfunction: Emerging Roles in Autism Spectrum Disorders
Neuroscience·2020· 50 citedOpen Access
Outside-in: Rethinking the etiology of autism spectrum disorders
Science·2019· 16 cited
Targeting Peripheral Somatosensory Neurons to Improve Tactile-Related Phenotypes in ASD Models
Cell·2019· 249 citedOpen Access
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
Cell·2019· 160 citedOpen Access
Wnt5a is essential for hippocampal dendritic maintenance and spatial learning and memory in adult mice
Proceedings of the National Academy of Sciences·2017· 80 citedOpen Access
The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn
Cell·2016· 427 citedOpen Access
Peripheral Mechanosensory Neuron Dysfunction Underlies Tactile and Behavioral Deficits in Mouse Models of ASDs
Cell·2016· 388 citedOpen Access
Control of spine maturation and pruning through proBDNF synthesized and released in dendrites
Molecular and Cellular Neuroscience·2015· 55 cited
Tools for Analyzing the Role of Local Protein Synthesis in Synaptic Plasticity
Neuromethods·2015
Distinct Roles for Somatically and Dendritically Synthesized Brain-Derived Neurotrophic Factor in Morphogenesis of Dendritic Spines
Journal of Neuroscience·2013· 86 citedOpen Access
THE ROLE OF LOCAL BDNF SYNTHESIS IN SPINE MORPHOGENESIS
DigitalGeorgetown (Georgetown University Library)·2013Open Access
BDNF Promotes Differentiation and Maturation of Adult-born Neurons through GABAergic Transmission
Journal of Neuroscience·2012· 277 citedOpen Access
Paternal care paradoxically increases offspring seizure susceptibility in the El mouse model of epilepsy
Epilepsy & Behavior·2007· 9 cited
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Frequent Co-authors

David D. Ginty(6), Baoji Xu(5), Christopher D. Harvey(4), Anda M. Chirila(3), Emily G. Waterhouse(3), Aniqa Tasnim(3), James P. Bohnslav(3), Nivanthika K. Wimalasena(3), Kelsey J. Clausing(3), Tomás Cruz(3), M Eugenia Chiappe(3), Clifford J. Woolf(3), Amira Abdelaziz(3), Mark W. Springel(2), Amanda Zimmerman(2), Alan J. Emanuel(2), Yu Dai(2), David A. Yarmolinsky(2), Adam D. Kashlan(2), Ilayda Alkislar(2)