Roger J. Davis

University of Massachusetts Chan Medical School — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

165h-index125.9kcitations853works1.32yr avg
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Research Topics

Melanoma and MAPK Pathways(173), Protein Kinase Regulation and GTPase Signaling(91), Cytokine Signaling Pathways and Interactions(68), NF-κB Signaling Pathways(62), Cell death mechanisms and regulation(48)

Publications849 total

A hypothalamus-liver-skeletal muscle axis controlled by JNK1 and FGF21 mediates olanzapine-induced insulin resistance in an intraperitoneal treatment in male mice
2026
JNK3 regulates β cell responses to incretins in human islets and mouse models
Journal of Clinical Investigation·2026Open Access
Structural and systems characterization of phosphorylation on metabolic enzymes identifies sex-specific metabolic reprogramming in obesity
Molecular Cell·2025· 2 citedOpen Access
JNK1 in SF1 neurons regulates the central action of thyroid hormones on hepatic lipid metabolism
Molecular Metabolism·2025· 1 citedOpen Access
Adipocyte MKK3 Increases in Human Obesity protecting against Insulin Resistance by p38β activation
2025Open Access
Mixed lineage kinase (MLK) controls tumor development and angiogenesis
Angiogenesis·2025· 2 citedOpen Access
Bipartite binding of the intrinsically disordered scaffold protein JIP1 to the kinase JNK1
Proceedings of the National Academy of Sciences·2025· 5 citedOpen Access
Differential Protective Roles of c-Jun N-terminal Kinase-2 in Nonparenchymal Liver Cells and Hepatocytes During Cholestasis
Cellular and Molecular Gastroenterology and Hepatology·2025Open Access
The structural basis of protective and nonprotective human monoclonal antibodies targeting the parainfluenza virus type 3 hemagglutinin-neuraminidase
Nature Communications·2024· 3 citedOpen Access
G12/13-mediated signaling stimulates hepatic glucose production and has a major impact on whole body glucose homeostasis
Nature Communications·2024· 4 citedOpen Access
Structural and systems characterization of phosphorylation on metabolic enzymes identifies sex-specific metabolic reprogramming in obesity
2024Open Access
Structural basis of homodimerization of the JNK scaffold protein JIP2 and its heterodimerization with JIP1
Structure·2024· 3 citedOpen Access
eLife assessment: E3 ubiquitin ligase Deltex facilitates the expansion of Wingless gradient and antagonizes Wingless signaling through a conserved mechanism of transcriptional effector Armadillo/β-catenin degradation
2024Open Access
eLife Assessment: E3 ubiquitin ligase Deltex facilitates the expansion of Wingless gradient and antagonizes Wingless signaling through a conserved mechanism of transcriptional effector Armadillo/β-catenin degradation
2024Open Access
Evaluating the effectiveness of ChatGPT in disseminating accurate and readable prostate cancer information
European Urology·2024
eLife assessment: Identification of CD133+ intercellsomes in intercellular communication to offset intracellular signal deficit
2023Open Access
Correction: Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3
Journal of Biological Chemistry·2023Open Access
eLife Assessment: Identification of CD133+ Intercellsomes in Intercellular Communication to Offset Intracellular Signal Deficit
2023Open Access
eLife Assessment: E3 ubiquitin ligase Deltex facilitates the expansion of Wingless gradient and antagonizes Wingless signaling through a conserved mechanism of transcriptional effector Armadillo/β-catenin degradation
2023Open Access
Reviewer #2 (Public Review): E3 ubiquitin ligase Deltex facilitates the expansion of Wingless gradient and antagonizes Wingless signaling through a conserved mechanism of transcriptional effector Armadillo/β-catenin degradation
2023Open Access
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Frequent Co-authors

G. de Zotti(11), J. M. Diego(8), Richard A. Flavell(7), P. A. R. Ade(7), N. Aghanim(7), M. Ashdown(7), J. Aumont(7), C. Baccigalupi(7), R. B. Barreiro(7), K. Benabed(7), A. Benoit-Lévy(7), P. Bielewicz(7), L. Bonavera(7), J. R. Bond(7), F. R. Bouchet(7), C. Burigana(7), R. C. Butler(7), J.-F. Cardoso(7), A. Challinor(7), A. Chamballu(7)