L. Earnest-Silveira

University of Melbourne — Australia

Medicine · Health Sciences

15h-index902citations28works0.02yr avg

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Research Topics

Hepatitis C virus research(25), Hepatitis B Virus Studies(21), Liver Disease Diagnosis and Treatment(8), Monoclonal and Polyclonal Antibodies Research(8), HIV Research and Treatment(3)

Publications28 total

97 cited

BMC Cancer·2019· 97 citedOpen Access

Pre-clinical evaluation of a quadrivalent HCV VLP vaccine in pigs following microneedle delivery

65 cited

Scientific Reports·2019· 65 citedOpen Access

A Hepatitis C Virus DNA Vaccine Encoding a Secreted, Oligomerized Form of Envelope Proteins Is Highly Immunogenic and Elicits Neutralizing Antibodies in Vaccinated Mice

34 cited

Frontiers in Immunology·2019· 34 citedOpen Access

Probing and pressing surfaces of hepatitis C virus-like particles

27 cited

Journal of Colloid and Interface Science·2019· 27 cited

Immunological responses following administration of a genotype 1a/1b/2/3a quadrivalent HCV VLP vaccine

43 cited

Scientific Reports·2018· 43 citedOpen Access

Antibody Responses to a Quadrivalent Hepatitis C Viral-Like Particle Vaccine Adjuvanted with Toll-Like Receptor 2 Agonists

15 cited

Viral Immunology·2018· 15 cited

Large scale production of a mammalian cell derived quadrivalent hepatitis C virus like particle vaccine

23 cited

Journal of Virological Methods·2016· 23 cited

Characterization of a hepatitis C virus-like particle vaccine produced in a human hepatocyte-derived cell line

33 cited

Journal of General Virology·2016· 33 cited

Hepatitis C virus-induced hepatocyte cell death and protection by inhibition of apoptosis

28 cited

Journal of General Virology·2014· 28 cited

Hepatitis C VLPs Delivered to Dendritic Cells by a TLR2 Targeting Lipopeptide Results in Enhanced Antibody and Cell-Mediated Responses

54 cited

PLoS ONE·2012· 54 citedOpen Access

816 DYSREGULATION OF HEPATOCYTE SIGNAL TRANSDUCTION, CIAP1 AND APOPTOSIS BY HEPATITIS C VIRUS

Journal of Hepatology·2011Open Access

794 NOVEL ADJUVANTS INCREASE HUMORAL NEUTRALISING ANTIBODY AND T CELL IMMUNE RESPONSES IN MHC CLASS I TRANSGENIC MICE TO RECOMBINANT MAMMALIAN CELL DERIVED HEPATITIS C VIRUS-LIKE-PARTICLES

Journal of Hepatology·2011Open Access

1127 HEPATITIS B VIRUS INDUCES LOSS OF CIAPl AND SENSITIVITY TO TNF-ALPHA IN PRIMARY HEPATOCYTES

Journal of Hepatology·2011

652 RECOMBINANT MAMMALIAN CELL DERIVED HEPATITIS C VIRUS LIKE PARTICLES INDUCE NEUTRALISING ANTIBODY AND B CELL RESPONSES TO HEPATITIS C VIRUS

Journal of Hepatology·2010Open Access

Dysregulation of hepatocyte cell cycle and cell viability by hepatitis B virus

12 cited

Virus Research·2009· 12 cited

899 RECOMBINANT MAMMALIAN CELL DERIVED HCV VIRUS LIKE PARTICLES TO INDUCE NEUTRALISING ANTIBODY RESPONSES TO HCV

Journal of Hepatology·2009

582 MODULATION OF AKT, NFKB ACTIVITY, APOPTOSIS AND CELL CYCLE IN HEPATOCYTES BY THE LAMIVUDINE RESISTANT RTM204I HBV MUTANT

Journal of Hepatology·2009Open Access

Fiber-modified recombinant adenoviral constructs encoding hepatitis C virus proteins induce potent HCV-specific T cell response

18 cited

Clinical Immunology·2008· 18 cited

Failure of Lamivudine to Reverse Hepatitis B Virus-Associated Changes in ERK, Akt and Cell Cycle Regulatory Proteins

13 cited

Antiviral Therapy·2008· 13 citedOpen Access

579 FAILURE OF LAMIVUDINE TO REVERSE HBV ASSOCIATED CHANGES IN ERK, AKT AND CELL CYCLE REGULATORY PROTEINS

Journal of Hepatology·2008

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Frequent Co-authors

Joseph Torresi(28), C.–Thomas Bock(14), David C. Jackson(11), Dale Christiansen(8), Eric J. Gowans(8), Brendon Y. Chua(7), Bernd Koeberlein(6), H. Zentgraf(6), Ruth Chin(5), Irene Boo(5), Heidi E. Drummer(5), John Silke(5), Susanne Franz(4), Branka Grubor‐Bauk(4), Ueli Nachbur(4), Hanswalter Zentgraf(3), Rey Chin(3), Aleksandra Bankovacki(3), Russell L. Chin(3), D. Johnson(3)