James Fikes

Biogen (United States) — United States

Immunology and Microbiology · Life Sciences

11h-index2.0kcitations32works3.72yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Immunotoxicology and immune responses(10), Animal testing and alternatives(8), Immune Response and Inflammation(3), RNA Interference and Gene Delivery(3), NF-κB Signaling Pathways(3)

Publications32 total

Inhibition of immune response reduces pathology in dorsal root ganglia and peripheral nerves in cynomolgus macaques following AAV gene therapy
Molecular Therapy — Methods & Clinical Development·2025· 1 citedOpen Access
Scientific and Regulatory Policy Committee Points to Consider: Review of the United States Food and Drug Administration (FDA) Guidance on Pathology Peer Review in Nonclinical Toxicology Studies
Toxicologic Pathology·2024· 4 cited
Adeno-Associated Virus-Mediated Dorsal Root Ganglion Toxicity in the New Zealand White Rabbit
Toxicologic Pathology·2024· 6 cited
Overview of the Role of Pathology in Product Discovery and Development
Elsevier eBooks·2023
Contributors
Elsevier eBooks·2023
Scientific and Regulatory Policy Committee Points to Consider: Primary Digital Histopathology Evaluation and Peer Review for Good Laboratory Practice (GLP) Nonclinical Toxicology Studies
Toxicologic Pathology·2022· 7 cited
Scientific and Regulatory Policy Committee Brief Communication: 2019 Survey on Use of Digital Histopathology Systems in Nonclinical Toxicology Studies
Toxicologic Pathology·2022· 6 cited
Antisense Oligonucleotide-Related Macrovesicular Vacuolation of Hippocampal Neurons in Nonhuman Primates
Toxicologic Pathology·2022· 8 cited
Contributors
Elsevier eBooks·2021
Pathology Peer Review
Elsevier eBooks·2021· 3 cited
Opinion on Performing Pathology Peer-Review During the Global Pandemic: Challenges and Opportunities
Toxicologic Pathology·2020· 5 citedOpen Access
Use of Severity Grades to Characterize Histopathologic Changes
Toxicologic Pathology·2018· 201 cited
A Diagnostic Approach for Rodent Progressive Cardiomyopathy and Like Lesions in Toxicology Studies up to 28 Days in the Sprague Dawley Rat (Part 2 of 2)
Toxicologic Pathology·2017· 6 citedOpen Access
A Diagnostic Approach for Rodent Progressive Cardiomyopathy and Like Lesions in Toxicology Studies up to 28 Days in the Sprague Dawley Rat (Part 1 of 2)
Toxicologic Pathology·2017· 9 citedOpen Access
Scientific and Regulatory Policy Committee Review
Toxicologic Pathology·2015· 19 cited
An acute rat in vivo screening model to predict compounds that alter blood glucose and/or insulin regulation
Journal of Pharmacological and Toxicological Methods·2013· 3 cited
Assessment of cisplatin-induced kidney injury using an integrated rodent platform
Toxicology and Applied Pharmacology·2013· 32 cited
Phospholipogenic Pharmaceuticals Are Associated with a Higher Incidence of Histological Findings than Nonphospholipogenic Pharmaceuticals in Preclinical Toxicology Studies
Journal of Toxicology·2012· 11 citedOpen Access
Role of TL1A in the Pathogenesis of Rheumatoid Arthritis
The Journal of Immunology·2009· 90 citedOpen Access
Uterine Infarctions in Cynomolgus Monkeys (<i>Macaca fascicularis</i>)
Veterinary Pathology·2007· 2 citedOpen Access
page 1 of 2Next →

Frequent Co-authors

Kenneth A. Schafer(4), Jerry F. Hardisty(4), Eric Tien(4), Daniel J. Patrick(3), Fairfield T. Bain(3), Cathy S. Carlson(3), Heath C. Thomas(3), Martin Lamb(3), Rick R. Adler(3), Branka Grubor(3), Thomas Forest(3), Famke Aeffner(3), Vanessa Schumacher(3), Cynthia J. Willson(3), M. G. O'Sullivan(3), Bindu Bennet(3), Frank J. Geoly(3), Paul A. Moore(2), David W. LaFleur(2), Jeffrey A. Carrell(2)