Maria Georgomanoli

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index311citations15works0.02yr avg
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Research Topics

Virus-based gene therapy research(5), CRISPR and Genetic Engineering(5), Hemoglobinopathies and Related Disorders(4), Acute Myeloid Leukemia Research(3), Pluripotent Stem Cells Research(3)

Publications15 total

JoVE Video Dataset
2023
Murine Dermal Lymphatic Endothelial Cell Isolation
Journal of Visualized Experiments·2023· 1 cited
The Optimized γ-Globin Lentiviral Vector GGHI-mB-3D Leads to Nearly Therapeutic HbF Levels In Vitro in CD34+ Cells from Sickle Cell Disease Patients
Viruses·2022· 7 citedOpen Access
Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells
Cell Reports·2020· 47 citedOpen Access
Modeling blood diseases with human induced pluripotent stem cells
Disease Models & Mechanisms·2019· 32 citedOpen Access
A Novel iPSC Model Reveals a Role for RUNX1 in the Maintenance of AML Leukemia Stem Cells
Blood·2018
A Novel BaEVRless-Pseudotyped γ-Globin Lentiviral Vector Drives High and Stable Fetal Hemoglobin Expression and Improves Thalassemic Erythropoiesis <i>In Vitro</i>
Human Gene Therapy·2018· 11 cited
Dissecting the Contributions of Cooperating Gene Mutations to Cancer Phenotypes and Drug Responses with Patient-Derived iPSCs
Stem Cell Reports·2018· 54 citedOpen Access
222. The LCR-Free Y-Globin Lentiviral Vector Combining Two HPFH Activating Elements Corrects Murine Thalassemic Phenotype In Vivo
Molecular Therapy·2016Open Access
Towards More Successful Gene Therapy Clinical Trials for &amp;#946;-Thalassemia
Current Molecular Medicine·2013· 9 cited
Characterization and comparative performance of lentiviral vector preparations concentrated by either one-step ultrafiltration or ultracentrifugation
Virus Research·2013· 31 cited
The New Self-Inactivating Lentiviral Vector for Thalassemia Gene Therapy Combining Two HPFH Activating Elements Corrects Human Thalassemic Hematopoietic Stem Cells
Human Gene Therapy·2011· 22 citedOpen Access
Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer
Blood·2010· 97 citedOpen Access
Novel insulated gamma globin SIN lentiviral vectors with the HPFH-2 enhancer and the −117 HPFH active promoter efficiently transducer thalassemic CD34+ cells and prevent their apoptosis
Blood Cells Molecules and Diseases·2008
Novel γ-Globin Gene Lentiviral Insulated Vectors Containing the HPFH-2 Enhancer and the Activating -117 HPFH Aγ-Promoter Mutation.
Blood·2006

Frequent Co-authors

Nicholas P. Anagnou(9), Eleni Papanikolaou(8), Ekati Drakopoulou(5), Eirini P. Papapetrou(4), Andriana G. Kotini(3), Josephine Wesely(2), Franco Izzo(2), Hanzhi Luo(2), Han Yuan(2), Christina S. Leslie(2), Dan A. Landau(2), Michael G. Kharas(2), Evangelos Stamateris(2), Fottes Panetsos(2), Carsten W. Lederer(2), Marina Kleanthous(2), Ersi Voskaridou(2), Racheal G. Akwii(2), Μαργαρίτα Λάμπρου(2), Andriana Plevriti(2)