Maria Li Lung

Chinese University of Hong Kong — Hong Kong

Biochemistry, Genetics and Molecular Biology · Life Sciences

55h-index8.0kcitations383works2.42yr avg
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Research Topics

RNA modifications and cancer(132), Cancer-related gene regulation(59), Viral-associated cancers and disorders(56), Cancer Genomics and Diagnostics(49), Cancer-related molecular mechanisms research(42)

Publications381 total

Patient-derived organoid xenografts model esophageal cancer cachexia and enable assessment of anti-inflammatory drug repositioning
iScience·2026Open Access
Oncogenic NFE2L2 mutations in plasma ctDNA and tumors are predictors and prognosticators of chemoradiation therapy in resectable esophageal squamous cell carcinoma
British Journal of Cancer·2025Open Access
A genome-wide association study integrated with single-cell and bulk profiles uncovers susceptibility genes for nasopharyngeal carcinoma involved in tumorigenesis via regulation of T cells
Genome biology·2025· 2 citedOpen Access
Characterizing chromosome instability reveals its association with lipid-associated macrophages and clonal evolution of lymph node metastasis in esophageal squamous cell carcinoma
Cancer Letters·2025· 5 cited
Abstract 6135: Characterization of monocytic-myeloid populations in the tumor microenvironment using patient-derived organoid xenograft models and macrophage-depleting therapies in esophageal squamous cell carcinoma
Cancer Research·2025
Integrative Transcriptome‐Wide Association Study With Expression Quantitative Trait Loci Colocalization Identifies a Causal VAMP8 Variant for Nasopharyngeal Carcinoma Susceptibility
Advanced Science·2025Open Access
Whole-exome sequencing association study reveals genetic effects on tumor microenvironment components in nasopharyngeal carcinoma
Journal of Clinical Investigation·2025· 9 citedOpen Access
ImmuneMirror for evaluation of the genomic and transcriptomic features of resistance to immunotherapy for gastrointestinal tract cancer: abridged secondary publication.
PubMed·2024
ΔNp63-restricted viral mimicry response impedes cancer cell viability and remodels tumor microenvironment in esophageal squamous cell carcinoma
Cancer Letters·2024· 6 citedOpen Access
Meta-analysis of Epstein-Barr virus genomes in Southern Chinese identifies genetic variants and high risk viral lineage associated with nasopharyngeal carcinoma
PLoS Pathogens·2024· 6 citedOpen Access
Abstract 3005: <i>Low-density lipoprotein receptor-related protein 1B</i> (<i>LRP1B</i>) depletion promotes tumorigenicity by modulating fibroblasts in the tumor microenvironment in esophageal squamous cell carcinoma
Cancer Research·2024Open Access
ΔNp63-restricted viral mimicry response impedes cancer cell viability and remodels tumor microenvironment in esophageal squamous cell carcinoma
2024· 1 citedOpen Access
Multigene Profiling of Circulating Tumor Cells in Esophageal Squamous Cell Carcinoma Identifies Prognostic Cancer Driver Genes Associated with Epithelial-Mesenchymal-Transition Progression and Chemoresistance
Cancers·2023· 3 citedOpen Access
Large-Scale Whole-Exome Sequencing Association Study Implicates Genetic Effects on Viral Oncogenesis and Tumor Microenvironment in Nasopharyngeal Carcinoma
2023Open Access
Circulating Tumor DNA Dynamics as Prognostic Markers in Locally Advanced and Metastatic Esophageal Squamous Cell Carcinoma
JAMA Surgery·2023· 31 citedOpen Access
198. MODELING CANCER CACHEXIA USING PATIENT TUMOR ORGANOID-DERIVED XENOGRAFTS IN ESOPHAGEAL SQUAMOUS CELL CARCINOMA
Diseases of the Esophagus·2023Open Access
359. NFE2L2 MUTATIONS ARE PREDICTIVE AND PROGNOSTIC OF TREATMENT OUTCOME IN RESECTABLE ESOPHAGEAL SQUAMOUS CELL CARCINOMA PATIENTS
Diseases of the Esophagus·2023Open Access
High-throughput identification of regulatory elements and functional assays to uncover susceptibility genes for nasopharyngeal carcinoma
The American Journal of Human Genetics·2023· 12 citedOpen Access
Genome-wide CRISPR/Cas9 screening identifies a targetable MEST-PURA interaction in cancer metastasis
EBioMedicine·2023· 25 citedOpen Access
THY1 (CD90) Maintains the Adherens Junctions in Nasopharyngeal Carcinoma via Inhibition of SRC Activation
Cancers·2023· 5 citedOpen Access
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Frequent Co-authors

Hong Lok Lung(14), Arthur Kwok Leung Cheung(12), Josephine Mun Yee Ko(12), Eric J. Stanbridge(12), Sai Wah Tsao(11), Yue Cheng(10), Wei Dai(9), Sai Wah Tsao(9), Kwok Wah Chan(9), Eugene R. Zabarovsky(9), Kwok Wai Lo(8), Dora Lai‐Wan Kwong(7), Honglin Chen(7), Simon Law(7), Hong Zheng(6), Wai Tong Ng(6), Chi Man Tsang(6), Yim Ling Yip(6), Daniel Chua(6), Victor Lee(5)