Nicholas Noinaj

Purdue University West Lafayette — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

35h-index6.5kcitations154works3.92yr avg

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Research Topics

Bacterial Genetics and Biotechnology(39), RNA and protein synthesis mechanisms(28), Bacterial Infections and Vaccines(19), Antibiotic Resistance in Bacteria(14), Enzyme Structure and Function(14)

Publications154 total

A periplasmic zinc capture protein enhances the resistance of Neisseria gonorrhoeae to nutritional immunity

Proceedings of the National Academy of Sciences·2025Open Access

Surface protein machineries in Gram-negative bacteria

1 cited

Journal of Cell Science·2025· 1 cited

Structural insights into outer membrane protein biogenesis in pathogenic Neisseria

Structure·2025Open Access

Characterization of the OMP biogenesis machinery in Fusobacterium nucleatum

1 cited

Structure·2025· 1 cited

LAP-Hsp60 complex modulates epithelial tight junction barrier

2025Open Access

Structural basis for nucleolin recognition of MYC promoter G-quadruplex

24 cited

Science·2025· 24 cited

BPS2025 - Decoding the mechanism of iron piracy in pathogenic Neisseria

Biophysical Journal·2025

An Adenosine Analogue Library Reveals Insights into Active Sites of Protein Arginine Methyltransferases and Enables the Discovery of a Selective PRMT4 Inhibitor

9 cited

Journal of Medicinal Chemistry·2024· 9 citedOpen Access

Structural characterization of the POTRA domains from A. baumannii reveals new conformations in BamA

Structure·2024Open Access

Structural basis and inhibition of outer membrane protein biogenesis in pathogenic Neisseria

Acta Crystallographica Section A Foundations and Advances·2023Open Access

Divergence and Convergence: Complexity Emerges in Crystal Engineering from an 8-mer DNA

12 cited

Journal of the American Chemical Society·2023· 12 cited

Targeting BAM for Novel Therapeutics against Pathogenic Gram-Negative Bacteria

22 cited

Antibiotics·2023· 22 citedOpen Access

Characterization of synthetic antigen binding fragments targeting Toc75 for the isolation of TOC in A. thaliana and P. sativum

3 cited

Structure·2023· 3 citedOpen Access

Engineering DNA Crystals toward Studying DNA–Guest Molecule Interactions

32 cited

Journal of the American Chemical Society·2023· 32 cited

Characterization of the β-barrel assembly machinery in fusobacterium

1 cited

Biophysical Journal·2023· 1 cited

BAM folds OMPs using a budding mechanism

Biophysical Journal·2023

Structure–Activity Relationship Studies of Venglustat on NTMT1 Inhibition

8 cited

Journal of Medicinal Chemistry·2023· 8 citedOpen Access

Point Mutations in TbpA Abrogate Human Transferrin Binding in Neisseria gonorrhoeae

3 cited

Infection and Immunity·2022· 3 citedOpen Access

Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors

11 cited

Journal of Medicinal Chemistry·2022· 11 citedOpen Access

Structural basis of AcrIF24 as an anti-CRISPR protein and transcriptional suppressor

10 cited

Nature Chemical Biology·2022· 10 citedOpen Access

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Frequent Co-authors

Susan K. Buchanan(31), Travis J. Barnard(7), James C. Gumbart(7), Trevor Lithgow(5), Cynthia Nau Cornelissen(5), Re‐Wen Wu(4), Adam J. Kuszak(4), J.W. Fairman(4), Karl Lundquist(4), Grzegorz Piszczek(4), Petra Lukacik(3), N. Easley(3), Jeremy Bakelar(3), Sarah E. Rollauer(3), Joel Selkrig(3), Mary A. Bosserman(3), Jürgen Rohr(3), Dongxing Chen(3), Rong Huang(3), Emad Tajkhorshid(2)