Makoto Oba

Kyoto Prefectural University of Medicine — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

43h-index6.1kcitations231works2.22yr avg
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Research Topics

RNA Interference and Gene Delivery(82), Advanced biosensing and bioanalysis techniques(58), Chemical Synthesis and Analysis(52), Crystallization and Solubility Studies(45), X-ray Diffraction in Crystallography(45)

Publications231 total

Pyrophosphate as a Phosphate Donor for the Design of Stable and pH-Responsive Calcium Nanoparticles for Biomacromolecule Encapsulation
Langmuir·2025
A Concise and Modular Approach to Generate Novel RORγ Agonists
Journal of Medicinal Chemistry·2025· 1 cited
Poly(sarcosine) and Poly(2-ethyl-2-oxazoline) Tethered To mRNA Provide Stealth Properties To mRNA Polyplexes
ACS Applied Nano Materials·2025· 3 citedOpen Access
Development of Cell-Penetrating Peptides and Their Application to DDS
Chemical and Pharmaceutical Bulletin·2025Open Access
Highly pure mRNA vaccine provides robust immunization against P. aeruginosa by minimizing type I interferon responses
Journal of Controlled Release·2025· 3 citedOpen Access
Rearrangement in Diamine‐Based Polyzwitterion Side Chains for the Modulated pH Responsiveness Regardless of Their Comparable p <i>K</i> <sub>a</sub> Values
Macromolecular Rapid Communications·2025· 1 cited
Front Cover: Redox‐Responsive Side Chain Structural Changes in a Seven‐Membered Cyclic α,α‐Disubstituted α‐Amino Acid with a Disulfide Bond Enable Reversible Conformational Changes in Peptides (ChemPlusChem 4/2025)
ChemPlusChem·2025Open Access
Redox‐Responsive Side Chain Structural Changes in a Seven‐Membered Cyclic α,α‐Disubstituted α‐Amino Acid with a Disulfide Bond Enable Reversible Conformational Changes in Peptides
ChemPlusChem·2025· 1 cited
Introduction to foldamers
Organic & Biomolecular Chemistry·2025
Plasmid DNA delivery using arginine-rich cell-penetrating <scp>l</scp>/<scp>d</scp>-peptides containing α-aminoisobutyric acids
Organic & Biomolecular Chemistry·2025
Visualization of the Plasmid DNA Delivery System by Complementary Fluorescence Labeling of Arginine-Rich Peptides
Chemical and Pharmaceutical Bulletin·2024· 2 citedOpen Access
Development of novel amphipathic stapled peptides as DDS carriers for intracellular delivery of nucleic acids
2024Open Access
Identification of Proteolysis Targeting Chimeras (PROTACs) for Lysine Demethylase 5 and Their Neurite Outgrowth-Promoting Activity
Chemical and Pharmaceutical Bulletin·2024· 6 citedOpen Access
Intracellular Delivery of Plasmid DNA Using Amphipathic Helical Cell-Penetrating Peptides Containing Dipropylglycine
Chemical and Pharmaceutical Bulletin·2024· 1 citedOpen Access
Identification of a novel histone H2A mono-ubiquitination-inhibiting cell-active small molecule
Bioorganic & Medicinal Chemistry Letters·2024· 1 cited
Poly(ethylene Glycol) (PEG)–OligoRNA Hybridization to mRNA Enables Fine‐Tuned Polyplex PEGylation for Spleen‐Targeted mRNA Delivery
Small Science·2024Open Access
Poly(ethylene Glycol) (PEG)–OligoRNA Hybridization to mRNA Enables Fine‐Tuned Polyplex PEGylation for Spleen‐Targeted mRNA Delivery
Small Science·2024· 15 citedOpen Access
Rational Design of Amphipathic Antimicrobial Peptides with Alternating L-/D-Amino Acids That Form Helical Structures
Chemical and Pharmaceutical Bulletin·2024· 6 citedOpen Access
Oligosarcosine Conjugation of Arginine-Rich Peptides Improves the Intracellular Delivery of Peptide/pDNA Complexes
ACS Biomaterials Science & Engineering·2023· 6 cited
Discovery of Selective Histone Deacetylase 1 and 2 Inhibitors: Screening of a Focused Library Constructed by Click Chemistry, Kinetic Binding Analysis, and Biological Evaluation
Journal of Medicinal Chemistry·2023· 17 citedOpen Access
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Frequent Co-authors

Kazunori Kataoka(34), Nobuhiro Nishiyama(25), Kanjiro Miyata(24), Takehiko Ishii(13), Hiroyuki Koyama(13), Masakazu Tanaka(12), Shigeto Fukushima(10), Keiji Itaka(9), Takahiro Nomoto(8), Yuichi Yamasaki(7), Yu Matsumoto(7), Masaaki Kurihara(7), Kensuke Osada(6), Satoshi Uchida(6), Mitsunobu R. Kano(6), Yosuke Demizu(6), Hiroko Yamashita(5), Takuma Kato(5), Yan Lee(4), Muri Han(4)