Eugenia Spanopoulou

Immunology and Microbiology · Life Sciences

23h-index3.3kcitations30works0.02yr avg
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Research Topics

T-cell and B-cell Immunology(17), Immune Cell Function and Interaction(13), DNA Repair Mechanisms(5), Nuclear Receptors and Signaling(5), Immunotherapy and Immune Responses(4)

Publications30 total

Αναστοχαστική Πράξη. Ο αποκλεισμός στο σχολείο
2010
Biochemistry of V(D)J Recombination
Current topics in microbiology and immunology·2005· 69 cited
Mutations in Conserved Regions of the Predicted RAG2 Kelch Repeats Block Initiation of V(D)J Recombination and Result in Primary Immunodeficiencies
Molecular and Cellular Biology·2000· 64 citedOpen Access
Definition of Minimal Domains of Interaction Within the Recombination-Activating Genes 1 and 2 Recombinase Complex
The Journal of Immunology·2000· 45 citedOpen Access
The RAG1 Homeodomain Recruits HMG1 and HMG2 To Facilitate Recombination Signal Sequence Binding and To Enhance the Intrinsic DNA-Bending Activity of RAG1-RAG2
Molecular and Cellular Biology·1999· 115 citedOpen Access
Molecular Cloning and Characterization of a Mouse Homolog of Bacterial ClpX, a Novel Mammalian Class II Member of the Hsp100/Clp Chaperone Family
Journal of Biological Chemistry·1999· 33 citedOpen Access
Thymic microenvironments, 3-D versus 2-D?
Seminars in Immunology·1999· 140 citedOpen Access
The Effect of Me2+ Cofactors at the Initial Stages of V(D)J Recombination
Journal of Biological Chemistry·1998· 40 citedOpen Access
Partial V(D)J Recombination Activity Leads to Omenn Syndrome
Cell·1998· 460 citedOpen Access
Immunoglobulin gene hypermutation in germinal centers is independent of the RAG‐1 V(D)J recombinase
Immunological Reviews·1998· 14 cited
Mycoplasma Superantigen Is a CDR3-dependent Ligand for the T Cell Antigen Receptor
The Journal of Experimental Medicine·1998· 55 citedOpen Access
A Basic Motif in the N-Terminal Region of RAG1 Enhances V(D)J Recombination Activity
Molecular and Cellular Biology·1997· 59 citedOpen Access
Neoteny in Lymphocytes: <i>Rag1</i> and <i>Rag2</i> Expression in Germinal Center B Cells
Science·1996· 266 cited
The Homeodomain Region of Rag-1 Reveals the Parallel Mechanisms of Bacterial and V(D)J Recombination
Cell·1996· 223 citedOpen Access
RAG1 Mediates Signal Sequence Recognition and Recruitment of RAG2 in V(D)J Recombination
Cell·1996· 198 citedOpen Access
Cellular and Molecular Analysis of Lymphoid Development Using RAG-Deficient Mice
International Reviews of Immunology·1996· 18 cited
Localization, interaction, and RNA binding properties of the V(D)J recombination-activating proteins RAG1 and RAG2
Immunity·1995· 99 citedOpen Access
TBP binding and the rate of transcription initiation from the human β-globin gene
Nucleic Acids Research·1995· 20 cited
Functional commitment to helper T cell lineage precedes positive selection and is independent of T cell receptor MHC specificity
Immunity·1994· 78 cited
Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice.
Genes & Development·1994· 423 citedOpen Access
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Frequent Co-authors

Frank Grosveld(8), Sandro Santagata(7), David Baltimore(5), David G. Schatz(4), Vincent Giguère(4), Daniel P. Silver(3), Vassilis Aidinis(3), Anna Villa(2), Fabio Bozzi(2), Luigi D. Notarangelo(2), Paolo Vezzoni(2), Shuhua Han(2), Biao Zheng(2), Fu-Hou Wang(2), Michael J. Difilippantonio(2), Catherine J. McMahan(2), Patricia Cortés(2), Dimitris Kioussis(2), Carlos A. Gómez(2), Heather M. Ladyman(2)