Paul Klenerman

John Radcliffe Hospital — United Kingdom

Immunology and Microbiology · Life Sciences

139h-index86.8kcitations1.2kworks6.72yr avg
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Research Topics

Immune Cell Function and Interaction(315), Hepatitis C virus research(279), T-cell and B-cell Immunology(204), SARS-CoV-2 and COVID-19 Research(191), HIV Research and Treatment(149)

Publications1.2k total

OP36 Longitudinal multi-omic profiling of peripheral blood in acute severe ulcerative colitis reveals a myeloid-driven, steroid-resistant, upadacitinib-sensitive cellular phenotype
Journal of Crohn s and Colitis·2026
Dynamic impact of bivalent COVID-19 vaccine boosters on systemic and mucosal antibody and T cell immunity
Scientific Reports·2025Open Access
Guidelines for T cell nomenclature
Nature reviews. Immunology·2025· 11 citedOpen Access
The development of a pan-genotypic T cell vaccine against hepatitis C virus using heterologous prime-boost strategies
Hepatology·2025
Anti-CMV IgG Titre Determines Organ-Specific Protection Towards Immune Checkpoint Blockade Induced Toxicities
2025Open Access
Acyclic graphs to define models of relationships between human cytomegalovirus, cardiovascular disease and all-cause mortality in UK Biobank
Philosophical Transactions of the Royal Society B Biological Sciences·2025· 1 citedOpen Access
S61 Protective early innate immune activation by mitochondrial antiviral signalling protein (MAVS) in bacterial pneumonia
2025
P238 Spatial transcriptomic profiling at single-cell resolution reveals lung responses to sterile injury
2025
Use of anti-CTLA4 as a molecular adjuvant to support dose sparing of adenoviral vectored vaccines 2800
The Journal of Immunology·2025Open Access
Navigating the Hepatic Immune Landscape With Fine Needle Aspiration of the Liver—An Emerging Technique
Liver International·2025Open Access
Genome-wide association and gene-virus interaction study of liver disease in hepatitis C virus-infected patients
2025Open Access
Interplay of host and viral genetic variations in modulating antibody responses to genotype 3a hepatitis C virus: Implications for vaccine design
Cell Reports·2025Open Access
P8 Concurrent chronic HBV infection and MASLD: prevalence and audit on management as per consensus recommendations from the BASL and BSG NALFD Special Interest Group
2025
MAIT and other innate-like T cells integrate adaptive immune responses to modulate interval-dependent reactogenicity to mRNA vaccines
Science Immunology·2025· 4 citedOpen Access
Dosing interval is a major factor determining the quality of T cells induced by SARS-CoV-2 mRNA and adenoviral vector vaccines
Science Immunology·2025· 3 citedOpen Access
Human tonsil organoids reveal innate pathways modulating humoral and cellular responses to ChAdOx1
PLoS Pathogens·2025· 3 citedOpen Access
Understanding and improving vaccine efficacy in older adults
Nature Aging·2025· 7 cited
Single-cell profiling of blood and cerebrospinal fluid in tuberculous meningitis
The Journal of Immunology·2025· 2 citedOpen Access
Early NK-cell and T-cell dysfunction marks progression to severe dengue in patients with obesity and healthy weight
Nature Communications·2025· 5 citedOpen Access
Hybrid B- and T-Cell Immunity Associates With Protection Against Breakthrough Infection After Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination in Avon Longitudinal Study of Parents and Children (ALSPAC) Participants
The Journal of Infectious Diseases·2025· 2 citedOpen Access
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Frequent Co-authors

Eleanor Barnes(17), Susanna Dunachie(13), Alexander J. Mentzer(11), Juthathip Mongkolsapaya(11), Philip Goulder(10), Julian C. Knight(10), David I. Stuart(10), Christina Dold(10), Gavin Screaton(10), J. Kenneth Baillie(9), Piyada Supasa(9), John Frater(9), Tao Dong(9), Andrew J. Pollard(9), Chang Liu(8), Donal Skelly(8), Ayako Kurioka(8), Bruce D. Walker(7), Lance Turtle(7), Peter Openshaw(7)