Donna Horncastle

Imperial College Healthcare NHS Trust — United Kingdom

Medicine · Health Sciences

12h-index769citations22works0.02yr avg
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Research Topics

Tuberculosis Research and Epidemiology(5), Chronic Myeloid Leukemia Treatments(5), Chronic Lymphocytic Leukemia Research(4), Infectious Diseases and Tuberculosis(4), Lymphoma Diagnosis and Treatment(3)

Publications22 total

Expression of EGFR, HER2, Phosphorylated ERK and Phosphorylated MEK in Colonic Neoplasms of Familial Adenomatous Polyposis Patients
Journal of Gastrointestinal Cancer·2011· 11 cited
The significance of tumour cell immunophenotype in myeloma and its impact on clinical outcome
Journal of Clinical Pathology·2009· 25 cited
CD20 expression in the HHV‐8‐infected lymphoid cells in multicentric Castleman disease
Histopathology·2009· 22 cited
Atherosclerotic intralesional haemorrhage moulds monocyte differentiation into a macrophage antioxidant phenotype bearing the hemoglobin scavenger receptor CD163
The FASEB Journal·2008
E-cadherin/Catenin Complex Status in Solid Pseudopapillary Tumor of the Pancreas
The American Journal of Surgical Pathology·2008· 92 cited
Absence of cyclin‐D2 and Bcl‐2 expression within the germinal centre type of diffuse large B‐cell lymphoma identifies a very good prognostic subgroup of patients
Histopathology·2007· 48 cited
Bone marrow trephine combined with immunohistochemistry is superior to bone marrow aspirate in follow-up of myeloma patients
Journal of Clinical Pathology·2007· 46 cited
Total CD34+ cells per 10 HPF in bone marrow trephines of patients with chronic myeloid leukaemia correlates with probability of complete cytogenetic response following imatinib treatment
Histopathology·2007
Monocyte-Dependent Fibroblast CXCL8 Secretion Occurs in Tuberculosis and Limits Survival of Mycobacteria within Macrophages
The Journal of Immunology·2007· 65 citedOpen Access
In vivo evidence for apoptosis in the bone marrow in systemic lupus erythematosus
Annals of the Rheumatic Diseases·2007· 49 citedOpen Access
Bcl-6 and c-Myc are rarely co-expressed in adult diffuse large B-cell lymphoma
Leukemia & lymphoma/Leukemia and lymphoma·2007· 7 cited
Monocyte-Astrocyte Networks Regulate Matrix Metalloproteinase Gene Expression and Secretion in Central Nervous System Tuberculosis In Vitro and In Vivo
The Journal of Immunology·2007· 50 cited
IFN' synergizes with IL‐1α to up‐regulate MMP‐9 secretion in a cellular model of central nervous system tuberculosis
The FASEB Journal·2006· 50 cited
Optimal processing of bone marrow trephine biopsy: the Hammersmith Protocol
Journal of Clinical Pathology·2006· 75 citedOpen Access
The expression of minichromosome maintenance protein‐2 in normal and abnormal megakaryocytes and comparison with the proliferative marker Ki‐67
British Journal of Haematology·2005· 10 citedOpen Access
<i>Mycobacterium tuberculosis</i> Up-Regulates Matrix Metalloproteinase-1 Secretion from Human Airway Epithelial Cells via a p38 MAPK Switch
The Journal of Immunology·2005· 111 citedOpen Access
<i>Mycobacterium tuberculosis</i> , but Not Vaccine BCG, Specifically Upregulates Matrix Metalloproteinase-1
American Journal of Respiratory and Critical Care Medicine·2005· 102 cited
Percentage of CD34<sup>+</sup> cells in a minimum 500‐cell count in bone marrow trephines of patients with chronic myeloid leukaemia provides the best correlation with aspirate blast count
British Journal of Haematology·2005· 5 cited
High Levels of CD34 Expression in Bone Marrow Trephines Predicts for Loss of Cytogenetic Response in Patients with in Chronic Phase Who Have Achieved Complete Cytogenetic Remission on Imatinib Therapy.
Blood·2004· 1 cited
Percentage of CD34 + Cells in a Minimum 500-Cell Count in Bone Marrow Trephines of Patients with Chronic Myeloid Leukaemia Provides the Best Correlation with Aspirate Blast Count.
Blood·2004
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Frequent Co-authors

Kikkeri N. Naresh(12), Irvin A. Lampert(10), Kay Elderfield(8), Victoria Elliot(6), Paul Elkington(5), Jon S. Friedland(5), Joseph J. Boyle(4), Jane F. Apperley(4), Cecilia O’Kane(3), David Marín(3), David Marin(3), J Howard(3), Robert K. Nuttall(2), Dylan R. Edwards(2), Mona El‐Bahrawy(2), James Harris(2), Manuel B. Graeber(2), Furrat Amen(2), Mark Bower(2), Amin Rahemtulla(2)