Tsuyoshi Ogiku

Mitsubishi Chemical (Japan) — Japan

Chemistry · Physical Sciences

18h-index817citations80works0.02yr avg
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Research Topics

Synthetic Organic Chemistry Methods(24), Plant-derived Lignans Synthesis and Bioactivity(24), Asymmetric Synthesis and Catalysis(15), Biological Activity of Diterpenoids and Biflavonoids(13), Phytochemistry and Biological Activities(11)

Publications80 total

ChemInform Abstract: A Diastereoselective Construction of Pyrazinoisoquinoline Skeletons via Tandem Cyclization of Phenylalanine Derivatives: A Facile Synthesis of Optically Active Pyrazinoisoquinolines.
ChemInform·2014
A diastereoselective construction of pyrazinoisoquinoline skeletons via tandem cyclization of phenylalanine derivatives: a facile synthesis of optically active pyrazinoisoquinolines
Tetrahedron·2014· 6 cited
ChemInform Abstract: Evaluation of Pyrrolin‐2‐one Derivatives Synthesized by a New Practical Method as Inhibitors of Plasminogen Activator inhibitor‐1 (PAI‐1).
ChemInform·2010
ChemInform Abstract: Synthesis and Evaluation of Pyrrolin‐2‐one Compounds, a Series of Plasminogen Activator Inhibitor‐1 Inhibitors.
ChemInform·2010
Synthesis and evaluation of 1,4-diphenylbutadiene derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) production
Bioorganic & Medicinal Chemistry·2010· 8 cited
Evaluation of pyrrolin-2-one derivatives synthesized by a new practical method as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
Bioorganic & Medicinal Chemistry Letters·2009· 13 citedOpen Access
Practical Synthetic Method of (2<i>Z</i>,3<i>E</i>)-1,4-Diphenylbutadiene T-2639, an Inhibitor of Plasminogen Activator Inhibitor-1 (PAI-1) Production
Organic Process Research & Development·2009· 6 cited
Traceless solid-phase synthesis of multiple sulfonamide-containing cyclic sulfides exploiting microwave irradiation
Tetrahedron Letters·2009· 10 cited
CCDC 705024: Experimental Crystal Structure Determination
The Cambridge Structural Database·2009Open Access
Synthesis and Evaluation of Pyrrolin-2-one Compounds, a Series of Plasminogen Activator Inhibitor-1 Inhibitors
Chemical and Pharmaceutical Bulletin·2009· 19 citedOpen Access
Design, synthesis, and evaluation of orally active inhibitors of plasminogen activator inhibitor-1 (PAI-1) production
Bioorganic & Medicinal Chemistry Letters·2008· 14 cited
A Traceless Solid-phase Synthesis of 1,4-Diazepan-2-ones
Chemistry Letters·2008· 3 cited
Combination of Virtual Screening and High Throughput Gene Profiling for Identification of Novel Liver X Receptor Modulators
Journal of Medicinal Chemistry·2008· 14 cited
Traceless Solid-Phase Preparation of Thiomorpholin-3-ones
Synfacts·2008
ChemInform Abstract: Facile Stereoselective Synthesis of (E)‐ and (Z)‐α‐Substituted Cinnamates: Stereospecific Dehydration Reaction with 1‐Ethyl‐3‐(3‐dimethylaminopropyl)carbodiimide (EDC) and Copper(II) Chloride.
ChemInform·2008
A traceless solid phase synthesis of thiomorpholin-3-ones
Tetrahedron Letters·2007· 13 cited
A Traceless Solid-phase Synthesis of 1,4-Diazabicyclo[3,3,1]octan-3-ones
Chemistry Letters·2007· 8 cited
Facile stereoselective synthesis of (E)- and (Z)-α-substituted cinnamates: stereospecific dehydration reaction with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) and copper(II) chloride
Tetrahedron·2007· 21 cited
Synthesis of 1,4‐Diphenylbutadiene Derivatives: Novel Inducer of Tissue‐Type Plasminogen Activator (t‐PA) in Cultured Bovine Endothelial Cells.
ChemInform·2007
Synthesis of 1,4-Diphenylbutadiene Derivatives: Novel Inducer of Tissue-Type Plasminogen Activator (t-PA) in Cultured Bovine Endothelial Cells
Chemical and Pharmaceutical Bulletin·2006· 13 citedOpen Access
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Frequent Co-authors

Hiroshi Ohmizu(30), Tameo Iwasaki(27), Shin�ichi Yoshida(11), Masami Takahashi(10), Tooru Kuroda(8), Hiroshi Sai(7), Kazuhiko Kondo(7), Akio Ohtani(5), Osamu Sakurai(4), Hiroshi Horikawa(4), Hiroshi Miyazaki(4), Yasunori Moritani(4), Kunio Saruta(4), Shigeo Yoshida(4), Dale L. Boger(3), Jeffrey A. McKie(3), Takahide Nishi(3), Takashi Nishitani(2), Masahito Hayashi(2), Hiroyuki Takeda(2)