Chafic Karam

Hospital of the University of Pennsylvania — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index2.6kcitations180works4.12yr avg
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Research Topics

Amyloidosis: Diagnosis, Treatment, Outcomes(42), Peripheral Neuropathies and Disorders(32), Hereditary Neurological Disorders(24), Amyotrophic Lateral Sclerosis Research(23), Neurogenetic and Muscular Disorders Research(16)

Publications180 total

Clinical Utility of Serum Neurofilament Light Chain in Peripheral Neuropathy
Muscle & Nerve·2025Open Access
Effectiveness and Utility of Genetic Testing in Establishing a Diagnosis of Hereditary Transthyretin Amyloidosis
Journal of Clinical Medicine·2025· 1 citedOpen Access
77PADHERE+ trial interim analysis: long-term safety and efficacy of efgartigimod in chronic inflammatory demyelinating polyneuropathy (CIDP)
Neuromuscular Disorders·2025
Characteristics, Treatment Patterns, Healthcare Resource Utilization, and Costs Among Patients with Multifocal Motor Neuropathy: A US Claims Database Cohort Study
Journal of health economics and outcomes research·2025Open Access
D.7 Efgartigimod impact on I-RODS daily activity assessment in chronic inflammatory demyelinating polyneuropathy: post hoc analysis of Registrational ADHERE Study
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques·2025Open Access
P.033 Long-term efficacy of Efgartigimod PH20 SC in patients with chronic inflammatory demyelinating polyneuropathy: interim results from the ADHERE+ study
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques·2025Open Access
Real-world Characteristics and Disease Management for a Virtual Longitudinal Cohort of Patients with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) (P10-11.034)
Neurology·2025
Amyloid Spikes on Optical Coherence Tomography Demonstrating Ocular Involvement in ATTRv Amyloidosis
Neurology·2025
Factors associated with financial toxicity in patients with transthyretin amyloidosis: results from Amyloidosis Research Consortium’s treatment affordability patient and caregiver survey
Amyloid·2025· 1 cited
Treatment Patterns, Healthcare Resource Utilization, and Costs Among Patients with Multifocal Motor Neuropathy: A US Claims Database Cohort Study
Journal of health economics and outcomes research·2025Open Access
Navigating the switch from IVIG to FcRn inhibition in CIDP: Clinical insights
Journal of the Neurological Sciences·2024· 2 cited
Hereditary Transthyretin Amyloidosis in Patients Referred to a Genetic Testing Program
Journal of the American Heart Association·2024· 10 citedOpen Access
The journey to diagnosis of wild-type transthyretin-mediated (ATTRwt) amyloidosis: a path with multisystem involvement
Orphanet Journal of Rare Diseases·2024· 9 citedOpen Access
PRX004 in variant amyloid transthyretin (ATTRv) amyloidosis: results of a phase 1, open-label, dose-escalation study
Amyloid·2024· 30 citedOpen Access
Anti–Myelin-Associated Glycoprotein Neuropathy
Neurology Clinical Practice·2024Open Access
Clinical Reasoning: A 61-Year-Old Man With Progressive Right Leg Numbness and Weakness
Neurology·2024
Clinical Reasoning: A 49-Year-Old Man With Progressive Numbness, Gait Instability, and Tremors
Neurology·2024Open Access
Rapid screening for inflammatory neuropathies by standardized clinical criteria
UNC Libraries·2024Open Access
Combined clinical, structural and cellular studies discriminate pathogenic and benign TRPV4 variants
Brain·2024· 6 citedOpen Access
Mononeuropathy Due to Inflammatory Pseudotumor of Nerve
Neurology·2024
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Frequent Co-authors

Stephen N. Scelsa(9), Shafeeq Ladha(8), Sami Khella(8), Sabrina Paganoni(7), Namita Goyal(7), P. James B. Dyck(7), James Wymer(6), Colin Quinn(6), Tuan Vu(6), Thomas H. Brannagan(6), James B. Caress(5), Stephen A. Goutman(5), Daragh Heitzman(5), Carlayne E. Jackson(5), Andrea Swenson(5), Gary L. Pattee(5), Merit Cudkowicz(5), Mazen M. Dimachkie(5), Angela Genge(5), Stephen B. Heitner(5)