Nicholas J. Laping

Biochemistry, Genetics and Molecular Biology · Life Sciences

38h-index8.0kcitations101works0.02yr avg
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Research Topics

TGF-β signaling in diseases(16), Urinary Bladder and Prostate Research(14), S100 Proteins and Annexins(11), Clusterin in disease pathology(9), Estrogen and related hormone effects(8)

Publications101 total

Discovery of Isohexide Bisglycolamides as Inhibitors of the Integrated Stress Response
ACS Medicinal Chemistry Letters·2026Open Access
Supplementary Data from Development of a Small-Molecule Serum- and Glucocorticoid-Regulated Kinase-1 Antagonist and Its Evaluation as a Prostate Cancer Therapeutic
2023Open Access
Supplementary Data from Development of a Small-Molecule Serum- and Glucocorticoid-Regulated Kinase-1 Antagonist and Its Evaluation as a Prostate Cancer Therapeutic
2023Open Access
Data from Development of a Small-Molecule Serum- and Glucocorticoid-Regulated Kinase-1 Antagonist and Its Evaluation as a Prostate Cancer Therapeutic
2023Open Access
Data from Development of a Small-Molecule Serum- and Glucocorticoid-Regulated Kinase-1 Antagonist and Its Evaluation as a Prostate Cancer Therapeutic
2023Open Access
Broad Kinase Inhibition Mitigates Early Neuronal Dysfunction in Tauopathy
International Journal of Molecular Sciences·2021· 9 citedOpen Access
Sustained elevation of MG53 in the bloodstream increases tissue regenerative capacity without compromising metabolic function
Nature Communications·2019· 65 citedOpen Access
PERK inhibition delays neurodegeneration and improves motor function in a mouse model of Marinesco-Sjögren syndrome
Human Molecular Genetics·2018· 49 citedOpen Access
TLR2 agonism reverses chemotherapy-induced neutropenia in Macaca fascicularis
Blood Advances·2017· 4 citedOpen Access
the angiotensin II receptor antagonist, eprosartan Gene expression in rats with renal disease treated with
2015
RatFibers Innervating the Urinary Bladder of the Effects of Opioids on Mechanosensitive Pelvic Nerve
2015
Abstract C134: EN3356, a novel CYP17A inhibitor for the treatment of castration resistant prostate cancer.
Molecular Cancer Therapeutics·2013· 1 cited
Effects of Rho‐kinase inhibition on myosin light chain phosphorylation and obstruction‐induced detrusor overactivity
International Journal of Urology·2013· 6 cited
Voltage-gated Na+ Channel Blockers Reduce Functional Bladder Capacity in the Conscious Spontaneously Hypertensive Rat
Urology·2012· 4 cited
N-((1S)-1-{[4-((2S)-2-{[2,4-Dichlorophenyl)sulfonyl]amino} -3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl-1-benzothiophene-2- carboxamide (GSK1016790A), a novel and potent transient receptor potential vanilloid 4 channel agonist induces urinary bladder contraction and hyperactivity: Part I (Journal of Pharmacology and Experimental Therapeutics (2008) 326, (432-442))
Journal of Pharmacology and Experimental Therapeutics·2011· 5 cited
Markers Associated with Sex Differences in Methamphetamine-Induced Striatal Dopamine Neurotoxicity
Current Neuropharmacology·2011· 15 citedOpen Access
Novel 3-Oxazolidinedione-6-aryl-pyridinones as Potent, Selective, and Orally Active EP<sub>3</sub> Receptor Antagonists
ACS Medicinal Chemistry Letters·2010· 16 citedOpen Access
Improving the developability profile of pyrrolidine progesterone receptor partial agonists
Bioorganic & Medicinal Chemistry Letters·2009· 12 citedOpen Access
Estrogen-induced stromal cell-derived factor-1 (SDF-1/Cxcl12) expression is repressed by progesterone and by Selective Estrogen Receptor Modulators via estrogen receptor α in rat uterine cells and tissues
Steroids·2009· 37 cited
Effect of Estrogen and Progesterone on Urodynamics in the Conscious Rat
Urology·2009· 12 cited
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Frequent Co-authors

Caleb E. Finch(11), Nancy R. Nichols(9), Eugene T. Grygielko(8), Barbara A. Olson(8), Jonathan Day(8), David P. Brooks(7), Erin S. R. Lashinger(5), Lisa A. Leon(5), Xin Su(5), John D. Harling(4), Irina Rozovsky(4), Todd E. Morgan(4), Richard M. Edwards(4), James F. Callahan(3), Laramie M. Gaster(3), Christopher Tweed(3), Steve A. Johnson(3), Anthony C. Sulpizio(3), Françoise Gellibert(3), Christine G. Schnackenberg(3)