Samuel Constant

Genkyotex (Switzerland) — Switzerland

Medicine · Health Sciences

28h-index2.9kcitations169works1.82yr avg
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Research Topics

Respiratory viral infections research(38), Inhalation and Respiratory Drug Delivery(28), Asthma and respiratory diseases(13), Influenza Virus Research Studies(12), SARS-CoV-2 and COVID-19 Research(11)

Publications168 total

Human airway organoids as a high-throughput screening platform for antiviral natural products discovery
2026
Bovine-derived influenza A virus (H5N1) shows efficient replication in well-differentiated human nasal epithelial cells without requiring genetic adaptation
2026Open Access
An innovative approach for anti-respiratory syncytial virus compound discovery from plant extracts, combining high-throughput screening and metabolomics
Biomedicine & Pharmacotherapy·2026· 1 citedOpen Access
Local tolerance and innate immune activation of primary human respiratory cells exposed to flagellin
2025Open Access
Early-Life Commensal Lung Bacteria Modulate Immune Responses and Susceptibility to RSV Infection in Neonatal Mice
2025
Flagellin-mediated TLR5 activation enhances innate immune responses in healthy and diseased human airway epithelium
2025· 1 citedOpen Access
A 3D-based immunofluorescence platform for characterizing COPD pathology and evaluating treatments in whole airway tissue models
2025
In vitro primary human alveolar epithelium/endothelium and fibroblast model: a tool for investigating IPF and treatment strategies
2025
P29-08 Development of a novel in vitro platform for the detection of profibrotic compounds based on primary human alveolar epithelium
Toxicology Letters·2025
CEC01-03 The current biological understanding of the respiratory tract, the in vitro models available as well as their use
Toxicology Letters·2025
Silicon Carbide Nanowires Impair Mucociliary Clearance-Mediated Innate Immunity in Primary Human Bronchial Epithelial Cells
ACS Nano·2025· 2 citedOpen Access
Influenza A(H1N1)pdm09 virus resistance to baloxavir, oseltamivir and sialic acid mimetics in single and dual therapies: Insights from human airway epithelia and murine models
Antiviral Research·2025· 3 citedOpen Access
A Novel In Vitro Primary Human Alveolar Model (AlveolAir™) for H1N1 and SARS-CoV-2 Infection and Antiviral Screening
Microorganisms·2025· 4 citedOpen Access
Evaluation of a non-animal toolbox informed by adverse outcome pathways for human inhalation safety
Frontiers in Toxicology·2025· 4 citedOpen Access
Rheological comparison of sputum and reconstituted airway epithelium mucus
Scientific Reports·2024· 6 citedOpen Access
Development of Broad‐Spectrum β‐Cyclodextrins‐Based Nanomaterials Against Influenza Viruses
Journal of Medical Virology·2024· 6 citedOpen Access
Minimum information for reporting on the TEER (trans-epithelial/endothelial electrical resistance) assay (MIRTA)
Archives of Toxicology·2024· 8 citedOpen Access
Multidrug Combinations against SARS-CoV-2 Using GS-441524 or Ivermectin with Molnupiravir and/or Nirmatrelvir in Reconstituted Human Nasal Airway Epithelia
Pharmaceutics·2024· 1 citedOpen Access
Late Breaking Abstract - Comparison of Ex Vivo Airway Epithelium of Transplant Recipients
Transplantation·2024
Astodrimer sodium nasal spray forms a barrier to SARS-CoV-2 in vitro and preserves normal mucociliary function in human nasal epithelium
Scientific Reports·2024· 1 citedOpen Access
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Frequent Co-authors

Song Huang(21), Jérôme Lacour(13), Caroline Tapparel(12), Laurent Kaiser(8), Ludovic Wiszniewski(7), Jessica Müller(6), Simone Tortoioli(5), David Linder(5), Valeria Cagno(4), Manel Essaidi-Laziosi(4), Bernadett Boda(4), Frédéric Buron(4), Andrés Pizzorno(3), Blandine Padey(3), Thomas Julien(3), Bruno Lina(3), Olivier Terrier(3), Manuel Rosa‐Calatrava(3), Francesco Stellacci(3), Isabelle Piuz(3)