Oriana Mandolfo

Manchester Academic Health Science Centre — United Kingdom

Medicine · Health Sciences

3h-index48citations11works1.02yr avg
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Research Topics

Lysosomal Storage Disorders Research(9), Cellular transport and secretion(2), Protease and Inhibitor Mechanisms(2), Trypanosoma species research and implications(2), S100 Proteins and Annexins(2)

Publications11 total

Collagen fibril formation at the plasma membrane occurs independently from collagen secretion
Wellcome Open Research·2025Open Access
Generation of a novel immunodeficient mouse model of Mucopolysaccharidosis type IIIA to test human stem cell-based therapies
Molecular Genetics and Metabolism·2024· 3 citedOpen Access
Systemic immune challenge exacerbates neurodegeneration in a model of neurological lysosomal disease
EMBO Molecular Medicine·2024Open Access
Collagen fibril formation at the plasma membrane occurs independently from collagen secretion
2024· 2 citedOpen Access
Systemic inflammation leads to neuronal loss and exacerbates behavioural deficits in a mouse model of MPS IIIA
Molecular Genetics and Metabolism·2024
Establishment of the Effectiveness of Early Versus Late Stem Cell Gene Therapy in Mucopolysaccharidosis II for Treating Central Versus Peripheral Disease
Human Gene Therapy·2023· 5 citedOpen Access
Developing an iPSC-based neural gene therapy approach for MPS IIIA
Molecular Genetics and Metabolism·2023
Gene-modified neural progenitor cells for the treatment of neuropathic lysosomal storage diseases
Neural Regeneration Research·2023· 2 citedOpen Access
Innate Immunity in Mucopolysaccharide Diseases
International Journal of Molecular Sciences·2022· 36 citedOpen Access
Systemic immune challenges exacerbate inflammation and cognitive decline in a mouse model of MPS IIIA
Molecular Genetics and Metabolism·2022
Pathology and treatment of Mucopolysaccharidosis type IIIA
Research Explorer (The University of Manchester)

Frequent Co-authors

Brian Bigger(10), Helen Parker(5), Yuko Ishikawa Learmonth(4), Claire O’Leary(3), Rebecca Holley(3), Aiyin Liao(2), Asma’u Usman(2), Tristan R. McKay(2), Adam Pickard(2), Richa Garva(2), Antony Adamson(2), Ben C. Calverley(2), Anna Hoyle(2), Christina Hayward(2), David G. Spiller(2), Yinhui Lu(2), Nigel W. Hodson(2), George Bou–Gharios(2), Joe Swift(2), Karl E. Kadler(2)