Jiejie Geng

Xijing Hospital — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

17h-index3.0kcitations24works28.32yr avg
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Research Topics

Signaling Pathways in Disease(13), COVID-19 Clinical Research Studies(6), Immune Cell Function and Interaction(6), SARS-CoV-2 and COVID-19 Research(5), T-cell and B-cell Immunology(3)

Publications24 total

HLA-B27 modulates the composition of the gut microbiota and drives a proinflammatory intestinal microecology
Human Immunology·2025Open Access
Spatial and single-cell transcriptomics reveal cellular heterogeneity and a novel cancer-promoting Treg cell subset in human clear-cell renal cell carcinoma
Journal for ImmunoTherapy of Cancer·2025· 19 citedOpen Access
Fragile Treg cells: Traitors in immune homeostasis?
Pharmacological Research·2024· 13 citedOpen Access
Inhibition of ferroptosis rescues M2 macrophages and alleviates arthritis by suppressing the HMGB1/TLR4/STAT3 axis in M1 macrophages
Redox Biology·2024· 81 citedOpen Access
Di-methylation of CD147-K234 Promotes the Progression of NSCLC by Enhancing Lactate Export
Cell Metabolism·2023· 7 citedOpen Access
Meplazumab in hospitalized adults with severe COVID-19 (DEFLECT): a multicenter, seamless phase 2/3, randomized, third-party double-blind clinical trial
Signal Transduction and Targeted Therapy·2023· 16 citedOpen Access
Immunological and metabolic characteristics of the Omicron variants infection
Signal Transduction and Targeted Therapy·2023· 7 citedOpen Access
CD147 contributes to SARS-CoV-2-induced pulmonary fibrosis
Signal Transduction and Targeted Therapy·2022· 60 citedOpen Access
TNF antagonist sensitizes synovial fibroblasts to ferroptotic cell death in collagen-induced arthritis mouse models
Nature Communications·2022· 243 citedOpen Access
CD98-induced CD147 signaling stabilizes the Foxp3 protein to maintain tissue homeostasis
Cellular and Molecular Immunology·2021· 18 citedOpen Access
NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2021· 105 citedOpen Access
CD147 antibody specifically and effectively inhibits infection and cytokine storm of SARS-CoV-2 and its variants delta, alpha, beta, and gamma
Signal Transduction and Targeted Therapy·2021· 98 citedOpen Access
Safety and efficacy of meplazumab in healthy volunteers and COVID-19 patients: a randomized phase 1 and an exploratory phase 2 trial
Signal Transduction and Targeted Therapy·2021· 65 citedOpen Access
CD147 antibody specifically and effectively inhibits infection and cytokine storm of SARS-CoV-2 variants
2021· 2 citedOpen Access
Di-methylation of CD147-K234 Promotes the Progression of NSCLC by Enhancing Lactate Export
Cell Metabolism·2021· 60 citedOpen Access
CD147-spike protein is a novel route for SARS-CoV-2 infection to host cells
Signal Transduction and Targeted Therapy·2020· 1.2k citedOpen Access
Meplazumab treats COVID-19 pneumonia: an open-labelled, concurrent controlled add-on clinical trial
2020· 170 citedOpen Access
SARS-CoV-2 invades host cells via a novel route: CD147-spike protein
2020· 692 citedOpen Access
CD147 deficiency in T cells prevents thymic involution by inhibiting the EMT process in TECs in the presence of TGFβ
Cellular and Molecular Immunology·2020· 28 citedOpen Access
Targeting CD147 for T to NK Lineage Reprogramming and Tumor Therapy
EBioMedicine·2017· 20 citedOpen Access
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Frequent Co-authors

Zhi‐Nan Chen(19), Ruo Chen(14), Xiuxuan Sun(12), Kui Zhang(12), Huijie Bian(12), Yumeng Zhu(11), Ping Zhu(11), Jiao Wu(10), Jinlin Miao(10), Lin Peng(9), Zhaohui Zheng(9), Zheng Zhang(7), Ping Zhu(7), Ke Wang(6), Zhuan Feng(6), Xianghui Fu(6), Fei Huo(6), Peng Du(5), Xu Yang(5), Gang Nan(5)