Jonathan Dickerhoff

Purdue University West Lafayette — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

19h-index996citations60works6.72yr avg
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Research Topics

DNA and Nucleic Acid Chemistry(50), Advanced biosensing and bioanalysis techniques(44), RNA Interference and Gene Delivery(28), RNA and protein synthesis mechanisms(8), Cancer therapeutics and mechanisms(5)

Publications60 total

NMR structure study of DNA G-quadruplexes and ligand complexes
Progress in Nuclear Magnetic Resonance Spectroscopy·2026
G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88
Cell Reports Physical Science·2025· 4 citedOpen Access
Abstract LB319: Nucleolin protein recognition of MYC oncogene promoter G-quadruplex
Cancer Research·2025
Structural basis for nucleolin recognition of <i>MYC</i> promoter G-quadruplex
Science·2025· 24 cited
Fibroblast growth receptor 1 is regulated by G-quadruplex in metastatic breast cancer
Communications Biology·2024· 5 citedOpen Access
Solution structures and effects of a platinum compound successively bound MYC G-quadruplex
Nucleic Acids Research·2024· 10 citedOpen Access
DNA G-Quadruplexes as Targets for Natural Product Drug Discovery
Engineering·2024· 14 citedOpen Access
Abstract PO2-18-06: Targeting fibroblast growth factor receptor (FGFR1) expression through G-quadruplex stabilization inhibits metastatic breast cancer
Cancer Research·2024
Design, Synthesis, and Investigation of the Pharmacokinetics and Anticancer Activities of Indenoisoquinoline Derivatives That Stabilize the G-Quadruplex in the <i>MYC</i> Promoter and Inhibit Topoisomerase I
Journal of Medicinal Chemistry·2024· 17 citedOpen Access
Abstract 5775: Structure and dynamics of the major <i>PDGFR-</i>β oncogene promoter G-quadruplex and insights into its cellular regulation
Cancer Research·2024
Negative Electron Transfer Collision-Induced Dissociation of G-Quadruplexes: Uncovering the Guanine Radical Anion Loss Pathway
Journal of the American Society for Mass Spectrometry·2024Open Access
Best method to determine DNA G-quadruplex folding: The 1H–13C HSQC NMR experiment
Methods·2023· 12 citedOpen Access
Gas-Phase Fragmentation as a Probe of G-Quadruplex Formation
Analytical Chemistry·2023· 4 citedOpen Access
Abstract 3840: High-resolution structural insights into targeting the <i>MYC</i> oncogene G-quadruplex with the quinoline derivative PEQ
Cancer Research·2023
Abstract 5005: Targeted down regulation of FGFR1 through G-quadruplex stabilization in metastatic breast cancer
Cancer Research·2023
Abstract 3842: Berberine recognition of the dGMP-bound PDGFR-β promoter G-quadruplex: Structural insight into specific drug targeting
Cancer Research·2023
Structures of G-Quadruplexes and Their Drug Interactions
2023
Structures of G-Quadruplexes and Their Drug Interactions
2023
DNA G-Quadruplex in Human Telomeres and Oncogene Promoters: Structures, Functions, and Small Molecule Targeting
Accounts of Chemical Research·2022· 131 citedOpen Access
Oxidative Damage Induces a Vacancy G-Quadruplex That Binds Guanine Metabolites: Solution Structure of a cGMP Fill-in Vacancy G-Quadruplex in the Oxidized <i>BLM</i> Gene Promoter
Journal of the American Chemical Society·2022· 27 citedOpen Access
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Frequent Co-authors

Danzhou Yang(27), Klaus Weisz(20), Kai‐Bo Wang(8), L. Haase(6), Guanhui Wu(5), Luying Chen(4), Uwe T. Bornscheuer(4), Clement Lin(4), Buket Onel(3), Andrea Funke(3), Beatrice Karg(3), Sabine Müller(3), Yichen Han(3), Muhammad Hassan Safdar(3), Michael K. Wendt(3), Saburo Sakai(2), Jixun Dai(2), Matthias Höhne(2), Nicole M. Brundridge(2), Scott A. McLuckey(2)