Milan R. Savani

The University of Texas Southwestern Medical Center — United States

Medicine · Health Sciences

10h-index991citations71works5.72yr avg
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Research Topics

Glioma Diagnosis and Treatment(19), Heat shock proteins research(16), ATP Synthase and ATPases Research(16), Mitochondrial Function and Pathology(15), RNA modifications and cancer(15)

Publications71 total

Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice
Zenodo (CERN European Organization for Nuclear Research)·2026Open Access
Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice
Zenodo (CERN European Organization for Nuclear Research)·2026Open Access
TMET-32. Cell-intrinsic pyrimidine synthesis pathway choice in human brain and glioma
Neuro-Oncology·2025Open Access
TMET-34. A Targetable Metabolic Signal Drives Neuronal Hyperexcitability and Glioma Aggressiveness
Neuro-Oncology·2025Open Access
Stable isotope tracing in human plasma-like medium reveals metabolic and immune modulation of the glioblastoma microenvironment
Neuro-Oncology·2025· 2 citedOpen Access
Gliomas phenocopy an inborn error of metabolism to drive neuronal activity and tumor growth
2025Open Access
Mutant IDH silences GSX2 to reprogram neural progenitor cell fate and promote gliomagenesis
2025· 1 citedOpen Access
Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice
2025· 1 citedOpen Access
194. Mesenchymal Progenitor Cell Polyamine Metabolism Promotes Trauma-induced Heterotopic Ossification
Plastic & Reconstructive Surgery Global Open·2025Open Access
A transcriptional biosensor reveals mechanisms of α-ketoglutarate signaling to chromatin
2025
Heme promotes venetoclax resistance in multiple myeloma through MEK-ERK signaling and purine biosynthesis
Blood·2024· 5 citedOpen Access
Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity
Science·2024· 65 citedOpen Access
Human Plasma-Like Medium Activates Immune Elements in Glioma
Neurosurgery·2024
Stable isotope tracing in human plasma-like medium reveals metabolic and immune modulation of the glioblastoma microenvironment
2023· 9 citedOpen Access
Emerging roles of nucleotide metabolism in cancer
Trends in cancer·2023· 58 citedOpen Access
Supplementary Figure Legends from A Modified Nucleoside 6-Thio-2′-Deoxyguanosine Exhibits Antitumor Activity in Gliomas
2023Open Access
Supplementary Figure from Antitumor Activity of a Mitochondrial-Targeted HSP90 Inhibitor in Gliomas
2023Open Access
Supplementary fig 2 from A Modified Nucleoside 6-Thio-2′-Deoxyguanosine Exhibits Antitumor Activity in Gliomas
2023Open Access
Data from Antitumor Activity of a Mitochondrial-Targeted HSP90 Inhibitor in Gliomas
2023Open Access
Supplementary Tables from A Modified Nucleoside 6-Thio-2′-Deoxyguanosine Exhibits Antitumor Activity in Gliomas
2023Open Access
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Frequent Co-authors

Kalil G. Abdullah(36), Gao Zhang(22), David M. Ashley(22), Samuel K. McBrayer(21), Shiyou Wei(21), Xiang Lin(21), Kuang Du(21), Yaohui Chen(21), Marilyne Labrie(21), Eric Sugarman(21), Michelle Bowie(21), Seethalakshmi Hariharan(21), Matthew S. Waitkus(21), Mustafa Khasraw(21), Yiling Lu(21), Meenhard Herlyn(21), Gordon B. Mills(21), Zhi Wei(21), Stephen T. Keir(21), Keith T. Flaherty(21)