Margrit Schwarz

Boehringer Ingelheim (United States) — United States

Medicine · Health Sciences

27h-index4.1kcitations41works0.02yr avg
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Research Topics

Drug Transport and Resistance Mechanisms(20), Cholesterol and Lipid Metabolism(18), Lipoproteins and Cardiovascular Health(9), Peroxisome Proliferator-Activated Receptors(7), Cancer, Lipids, and Metabolism(4)

Publications41 total

A molecular morphometric approach to diabetic kidney disease can link structure to function and outcome
Kidney International·2017· 77 citedOpen Access
Agonistic Human Antibodies Binding to Lecithin-Cholesterol Acyltransferase Modulate High Density Lipoprotein Metabolism
Journal of Biological Chemistry·2015· 31 citedOpen Access
The high-resolution crystal structure of human LCAT
Journal of Lipid Research·2015· 44 citedOpen Access
JLR 2014 Ason et al. No PCSK9-induced change in LDLR in E-ko
2015
PCSK9 inhibition fails to alter hepatic LDLR, circulating cholesterol, and atherosclerosis in the absence of ApoE
Journal of Lipid Research·2014· 79 citedOpen Access
JLR 2014 Ason et al.Suppl Data; no PCSK9-induced change in LDLR in E-ko
2014
Activation of FFA1 mediates GLP-1 secretion in mice. Evidence for allosterism at FFA1
Molecular and Cellular Endocrinology·2013· 88 cited
Abstract 13327: Modulation of Proprotein Convertase Subtilisin/Kexin Type 9 Function via Interaction with Apolipoprotein B/Lipoprotein Particles
Circulation·2012
Emerging Therapeutic Approaches for Dyslipidemias Associated with High LDL and Low HDL
2011
Abstract 5920: Lecithin Cholesterol Acyltransferase Promotes Reverse Cholesterol Transport and Attenuates Atherosclerosis Progression in New Zealand White Rabbits
Circulation·2009· 15 cited
A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates
Proceedings of the National Academy of Sciences·2009· 407 citedOpen Access
PO2-53 APOLIPOPROTEIN J (CLUSTERIN) BINDS TO AND REDUCES CYTOTOXICITY OF ENZYMATICALLY HYDROLYZED LOW DENSITY LIPOPROTEIN
Atherosclerosis Supplements·2007
Effects of peroxisome proliferator-activated receptor α/δ agonists on HDL-cholesterol in vervet monkeys
Journal of Lipid Research·2005· 88 citedOpen Access
Pathways and defects of bile acid synthesis: insights from in vitro and in vivo experimental models
Drug Discovery Today Disease Models·2004· 3 cited
Enterohepatic Circulation of Bile Salts in Farnesoid X Receptor-deficient Mice
Journal of Biological Chemistry·2003· 214 citedOpen Access
Severe sitosterolemia but unaffected biliary cholesterol content in ATP-binding cassette transporter ABCG5-null mice
Data Archiving and Networked Services (DANS)·2003
Sitosterolemia in ABCG5-Null mice is aggrevated upon activation of the liver X-receptor
Gastroenterology·2003Open Access
Effects of bile salt flux variations on the expression of hepatic bile salt transporters in vivo in rodents
University of Groningen research database (University of Groningen / Centre for Information Technology)·2003
Effects of bile salt flux variations on the expression of hepatic bile salt transporters in vivo in mice
Journal of Hepatology·2002· 68 cited
Loss of Nuclear Receptor SHP Impairs but Does Not Eliminate Negative Feedback Regulation of Bile Acid Synthesis
Developmental Cell·2002· 348 citedOpen Access
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Frequent Co-authors

David W. Russell(12), Folkert Kuipers(7), Joyce Chan(6), Susan Shetterly(5), Bei Shan(5), Simon Jackson(5), Wen‐Chen Yeh(4), Erik Lund(4), Daphne L. Davis(4), Monty Krieger(4), Attilio Rigotti(4), Ingemar Björkhem(4), Mei Di(4), Derek E. Piper(3), Jie Tang(3), Richard Lathe(3), Sara Berdy(3), John M. Dietschy(3), Stephen D. Turley(3), Brandon Ason(3)