John D. Brennan

McMaster University — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

60h-index11.5kcitations296works3.32yr avg
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Research Topics

Advanced biosensing and bioanalysis techniques(115), Biosensors and Analytical Detection(75), Advanced Biosensing Techniques and Applications(38), Bacteriophages and microbial interactions(29), DNA and Nucleic Acid Chemistry(24)

Publications296 total

A modified X10-23 DNAzyme that can better access large, structured RNA targets
Nucleic Acids Research·2025Open Access
Enhancing Clinical Detection Accuracy of Large Structured Viral RNA via DNAzyme Cleavage and Antisense‐Assisted Rolling Circle Amplification
Angewandte Chemie·2025· 4 citedOpen Access
Enhancing Clinical Detection Accuracy of Large Structured Viral RNA via DNAzyme Cleavage and Antisense‐Assisted Rolling Circle Amplification
Angewandte Chemie International Edition·2025· 5 citedOpen Access
A Combined Aptamer Pulldown‐DNAzyme Cleavage Assay for Intact Methicillin Resistant <i>Staphylococcus aureus</i> Cells
Angewandte Chemie International Edition·2025· 2 citedOpen Access
A Combined Aptamer Pulldown‐DNAzyme Cleavage Assay for Intact Methicillin Resistant <i>Staphylococcus aureus</i> Cells
Angewandte Chemie·2025
Making target sites in large structured RNAs accessible to RNA-cleaving DNAzymes through hybridization with synthetic DNA oligonucleotides
Nucleic Acids Research·2024· 10 citedOpen Access
The benefits of nursing professional governance nursing research and evidenced-based practice councils for new graduate nurses
Dialogues in Health·2024Open Access
<i>In‐vitro</i> Clinical Diagnostics using RNA‐Cleaving DNAzymes
ChemBioChem·2024· 5 citedOpen Access
A Rapid Sputum‐based Lateral Flow Assay for Airway Eosinophilia using an RNA‐cleaving DNAzyme Selected for Eosinophil Peroxidase
Angewandte Chemie·2023· 2 citedOpen Access
A Rapid Sputum‐based Lateral Flow Assay for Airway Eosinophilia using an RNA‐cleaving DNAzyme Selected for Eosinophil Peroxidase
Angewandte Chemie International Edition·2023· 19 citedOpen Access
Nucleic Acid Enzyme‐Activated CRISPR‐Cas12a With Circular CRISPR RNA for Biosensing
Small·2023· 44 citedOpen Access
Cover Feature: Comparative Characterization of Diverse DNA Aptamers for Recognition of Spike Proteins of Multiple SARS‐CoV‐2 Variants (Anal. Sens. 5/2023)
Analysis & Sensing·2023Open Access
Detection of Large Genomic RNA via DNAzyme‐Mediated RNA Cleavage and Rolling Circle Amplification: SARS‐CoV‐2 as a Model
Chemistry - A European Journal·2023· 16 citedOpen Access
Comparative Characterization of Diverse DNA Aptamers for Recognition of Spike Proteins of Multiple SARS‐CoV‐2 Variants
Analysis & Sensing·2023· 8 citedOpen Access
A sputum bioassay for airway eosinophilia using an eosinophil peroxidase aptamer
Scientific Reports·2022· 7 citedOpen Access
Three on Three: Universal and High-Affinity Molecular Recognition of the Symmetric Homotrimeric Spike Protein of SARS-CoV-2 with a Symmetric Homotrimeric Aptamer
Journal of the American Chemical Society·2022· 56 citedOpen Access
Generating Synthetic Images &amp; Data to Improve Object Detection in CCTV Footage from Public Transport
2022· 1 cited
An all-deoxyribonucleic acid circuit for detection of human telomerase activity in solution and on paper
Frontiers in Analytical Science·2022Open Access
On the Complexity of Object Detection on Real-world Public Transportation Images for Social Distancing Measurement
2022 International Joint Conference on Neural Networks (IJCNN)·2022
Hot Spot Initiation and Growth in Shock-Induced RDX through MD-informed Void Collapse Simulations
2022
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Frequent Co-authors

Yingfu Li(22), Carlos D. M. Filipe(13), Meng Liu(8), Robert Pelton(7), Sana Jahanshahi‐Anbuhi(7), Jimmy Gu(6), S. M. Zakir Hossain(5), Michael A. Brook(5), Clémence Sicard(4), Qiang Zhang(4), Balamurali Kannan(4), Roger E. Luckham(3), Kevin Pennings(3), M. Monsur Ali(3), Kulwinder K. Flora(3), Shirley H. J. Mei(3), Leyla Soleymani(3), Vincent Leung(3), Wen Jin(2), Erin M. McConnell(2)