Christophe Fremaux

Agricultural and Biological Sciences · Life Sciences

31h-index14.5kcitations53works1.02yr avg
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Research Topics

Probiotics and Fermented Foods(23), Bacteriophages and microbial interactions(20), CRISPR and Genetic Engineering(12), Genomics and Phylogenetic Studies(11), RNA and protein synthesis mechanisms(10)

Publications53 total

Unveiling the regulatory network controlling natural transformation in lactococci
PLoS Genetics·2024· 2 citedOpen Access
Unveiling the regulatory network controlling natural transformation in lactococci
2024Open Access
Expanding natural transformation to improve beneficial lactic acid bacteria
FEMS Microbiology Reviews·2022· 13 citedOpen Access
Dairy lactococcal and streptococcal phage–host interactions: an industrial perspective in an evolving phage landscape
FEMS Microbiology Reviews·2020· 49 cited
Novel Genus of Phages Infecting Streptococcus thermophilus: Genomic and Morphological Characterization
Applied and Environmental Microbiology·2020· 32 citedOpen Access
Author Correction: A mutation in the methionine aminopeptidase gene provides phage resistance in Streptococcus thermophilus
Scientific Reports·2020Open Access
A mutation in the methionine aminopeptidase gene provides phage resistance in Streptococcus thermophilus
Scientific Reports·2019· 30 citedOpen Access
Widespread anti-CRISPR proteins in virulent bacteriophages inhibit a range of Cas9 proteins
Nature Communications·2018· 188 citedOpen Access
An anti-CRISPR from a virulent streptococcal phage inhibits Streptococcus pyogenes Cas9
Nature Microbiology·2017· 183 cited
Natural DNA Transformation Is Functional in Lactococcus lactis subsp. cremoris KW2
Applied and Environmental Microbiology·2017· 27 citedOpen Access
Genomic impact of CRISPR immunization against bacteriophages
Biochemical Society Transactions·2013· 61 cited
Phage mutations in response to <scp>CRISPR</scp> diversification in a bacterial population
Environmental Microbiology·2012· 118 cited
Phage-Induced Expression of CRISPR-Associated Proteins Is Revealed by Shotgun Proteomics in Streptococcus thermophilus
PLoS ONE·2012· 90 citedOpen Access
The fast milk acidifying phenotype of Streptococcus thermophilus can be acquired by natural transformation of the genomic island encoding the cell-envelope proteinase PrtS
Microbial Cell Factories·2011· 77 citedOpen Access
The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli
Nucleic Acids Research·2011· 832 citedOpen Access
Cas3 is a single‐stranded DNA nuclease and ATP‐dependent helicase in the CRISPR/Cas immune system
The EMBO Journal·2011· 447 citedOpen Access
The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA
Nature·2010· 2.3k cited
Development of a Versatile Procedure Based on Natural Transformation for Marker-Free Targeted Genetic Modification in <i>Streptococcus thermophilus</i>
Applied and Environmental Microbiology·2010· 53 citedOpen Access
A Novel Pheromone Quorum-Sensing System Controls the Development of Natural Competence in <i>Streptococcus thermophilus</i> and <i>Streptococcus salivarius</i>
Journal of Bacteriology·2009· 216 citedOpen Access
Development of a new method for the detection of lactic acid bacteria capable of protecting ham against Enterobacteriaceae
Letters in Applied Microbiology·2009· 7 cited
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Frequent Co-authors

Philippe Horvath(22), Y. Cenatiempo(13), Dennis Romero(11), Rodolphe Barrangou(10), Patrick Boyaval(10), Sylvain Moineau(10), Jean‐Marc Berjeaud(8), Todd R. Klaenhammer(7), Pascal Hols(6), Marie Henry de Frahan(5), Laetitia Fontaine(4), Geneviève M. Rousseau(4), Denise M. Tremblay(4), Laurence Simon(4), Franck Biet(4), Hélène Deveau(3), Changwoo Ahn(3), Nicolas Biteau(3), Frédéric Toussaint(3), Melissa Richards(2)